- Role of sul2 Gene Linked to Transposase in Resistance to Trimethoprim/Sulfamethoxazole Among Stenotrophomonas maltophilia Isolates
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Hu LF, Xu XH, Yang HF, Ye Y, Li JB
- KMID: 2373503
- Ann Lab Med.
- 2016 Jan;36(1):73-75.
- doi: 10.3343/alm.2016.36.1.73
No abstract available. -
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- Alteration of the SETBP1 Gene and Splicing Pathway Genes SF3B1, U2AF1, and SRSF2 in Childhood Acute Myeloid Leukemia
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Choi HW, Kim HR, Baek HJ, Kook H, Cho D, Shin JH, Suh SP, Ryang DW, Shin MG
- KMID: 2363158
- Ann Lab Med.
- 2015 Jan;35(1):118-122.
- doi: 10.3343/alm.2015.35.1.118
BACKGROUND: Recurrent somatic SET-binding protein 1 (SETBP1) and splicing pathway gene mutations have recently been found in atypical chronic myeloid leukemia and other hematologic malignancies. These mutations have been comprehensively... -
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- PRSS1, SPINK1, CFTR, and CTRC Pathogenic Variants in Korean Patients With Idiopathic Pancreatitis
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Cho SM, Shin S, Lee KA
- KMID: 2373594
- Ann Lab Med.
- 2016 Nov;36(6):555-560.
- doi: 10.3343/alm.2016.36.6.555
BACKGROUND: This study aimed to identify pathogenic variants of PRSS1, SPINK1, CFTR, and CTRC genes in Korean patients with idiopathic pancreatitis. METHODS: The study population consisted of 116 Korean subjects (65... -
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- Mutation analysis of p31(comet) gene, a negative regulator of Mad2, in human hepatocellular carcinoma
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Yun MY, Kim SB, Park S, Han CJ, Han YH, Yoon SH, Kim SH, Kim CM, Choi DW, Cho MH, Park GH, Lee KH
- KMID: 756074
- Exp Mol Med.
- 2007 Aug;39(4):508-513.
Failure of mitotic checkpoint machinery leads to the chromosomal missegregation and nuclear endoreduplication, thereby driving the emergence of aneuploidy and tetraploidy population. Although abnormal nuclear ploidy and the resulting impairment... -
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- Vitamin D3 up-regulated protein 1 controls the priming phase of liver regeneration
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Kwon HJ, Hong SK, Yoon WK, Nam KH, Choi IP, Kim DY, Kim HC, Won YS
- KMID: 1705555
- J Vet Sci.
- 2013 Sep;14(3):257-262.
- doi: 10.4142/jvs.2013.14.3.257
Vitamin D3 up-regulated protein 1 (VDUP1) is a potent growth suppressor that inhibits tumor cell proliferation and cell cycle progression when overexpressed. In a previous study, we showed that VDUP1... -
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- Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice
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Huang Z, Yu M, Tong S, Jia K, Liu R, Wang H, Li S, Ning Z
- KMID: 1784636
- J Vet Sci.
- 2014 Jun;15(2):173-177.
- doi: 10.4142/jvs.2014.15.2.173
Activation of the innate immune system requires recognition of pathogen-associated molecular patterns, such as NOD-like receptors. The NOD-like receptor protein 3 (NLRP3) inflammasome is involved in induction of the pro-inflammatory... -
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- Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression
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Kim YH, Kim GS, Baek JH
- KMID: 1081464
- Exp Mol Med.
- 2002 May;34(2):145-151.
The mechanism of inhibitory action of bisphosphonates on bone resorption is not fully elucidated. Osteoclast formation and activity are regulated by osteoblast-derived factors such as the osteoclast differentiating factor, receptor... -
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- A Polymorphism in the Microsomal Triglyceride Transfer Protein Can Predict the Response to Antiviral Therapy in Egyptian Patients with Chronic Hepatitis C Virus Genotype 4 Infection
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Saad Y, Shaker O, Nassar Y, Ahmad L, Said M, Esmat G
- KMID: 2070084
- Gut Liver.
- 2014 Nov;8(6):655-661.
- doi: 10.5009/gnl13374
BACKGROUND/AIMS: A polymorphism in the microsomal triglyceride transfer protein (MTP) is associated with hepatic fibrosis, and carriers showed higher levels of steatosis, higher levels of hepatitis C virus (HCV) RNA... -
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- Intravenous KITENIN shRNA Injection Suppresses Hepatic Metastasis and Recurrence of Colon Cancer in an Orthotopic Mouse Model
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Hwang JE, Shim HJ, Park YK, Cho SH, Bae WK, Kim DE, Kim KK, Chung IJ
- KMID: 1123443
- J Korean Med Sci.
- 2011 Nov;26(11):1439-1445.
- doi: 10.3346/jkms.2011.26.11.1439
KITENIN (KAI1 C-terminal interacting tetraspanin) promotes invasion and metastasis in mouse colon cancer models. In the present study, we evaluated the effects of KITENIN knockdown by intravenous administration of short... -
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- Mutations of SPINK1 and PRSS1 Gene in Korean Patients with Chronic Pancreatitis
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Lee KH, Yoon WJ, Ryu JK, Kim YT, Yoon YB, Kim CY
- KMID: 1113323
- Korean J Gastroenterol.
- 2004 Aug;44(2):93-98.
BACKGROUND/AIMS: It has been found that mutations of cationic trypsinogen gene (PRSS1) and serine protease inhibitor, Kazal type 1 gene (SPINK1) increase the susceptibility of chronic pancreatitis (CP). Specifically,... -
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- SPINK1 N34S Mutation as a Possible Cause of Chronic Pancreatitis in a Patient with Familial Background
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Oh HC, Lee TY, Kwon S, Lee SS, Seo DW, Lee SK, Kim MH
- KMID: 782875
- Korean J Gastroenterol.
- 2007 Jun;49(6):384-389.
New insight in the field of chronic pancreatitis was provided by the discovery of protease serine 1 (PRSS1) mutation, inherited by autosomal dominant trait in hereditary pancreatitis. Serine protease inhibior,... -
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- Deflazacort Increases Osteoclast Formation in Mouse Bone Marrow Culture and the Ratio of RANKL/OPG mRNA Expression in Marrow Stromal Cells
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Chung H, Kang YS, Hwang CS, Moon IK, Yim CH, Choi KH, Han KO, Jang HC, Yoon HK, Han IK
- KMID: 648360
- J Korean Med Sci.
- 2001 Dec;16(6):769-773.
- doi: 10.3346/jkms.2001.16.6.769
Information on precise effects of deflazacort on bone cell function, especially osteoclasts, is quite limited. Therefore, the present study was undertaken to test effects of deflazacort on osteoclast-like cell formation... -
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- A common mutation in cholesteryl ester transfer protein gene and plasma HDL cholesterol level before and after hormone replacement therapy in Korean postmenopausal women
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Choi HS, Park JB, Han KO, Yim CH, Jung HY, Jang HC, Yoon HK, Cho DH, Shin HH, Han IK
- KMID: 1129106
- Korean J Intern Med.
- 2002 Jun;17(2):83-87.
BACKGROUND: Plasma cholesteryl ester transfer protein (CETP) functions to transfer cholesteryl ester from HDL to triglyceride-rich lipoproteins and regulates plasma HDL cholesterol level. A common mutation, the exon 15 A... -
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