- Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease
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Han YS, Kim JM, Cho JS, Lee CS, Kim DE
- KMID: 2287717
- J Clin Neurol.
- 2005 Apr;1(1):81-91.
- doi: 10.3988/jcn.2005.1.1.81
BACKGROUND: The membrane permeability transition of mitochondria has been suggested to be involved in toxic and oxidative forms of cell injury. Mitochondrial dysfunction is considered to play a critical role... -
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- Stuttering Priapism happened in Sleep
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Song HD, Lee AG, Cho SY, Cho IR
- KMID: 2298779
- Korean J Androl.
- 2009 Apr;27(1):55-58.
Priapism is an abnormal persistent penile erection that continues for more than 4 hours, without sexual stimulation according to the definition of the AUA (American Urological Association) guideline on the... -
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- Chronic Low Dosing of Phosphodiesterase Type 5 Inhibitor for Erectile Dysfunction
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Sung HH, Lee SW
- KMID: 2315369
- Korean J Urol.
- 2012 Jun;53(6):377-385.
Oral phosphodiesterase type 5 (PDE5) inhibitors have provided non-invasive, effective, and well-tolerated treatments for patients with erectile dysfunction (ED). However, many patients with ED are unresponsive to 'on-demand' PDE5 inhibitors.... -
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- Treatment Strategy for Non-Responders to PDE5 Inhibitors
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Park NC, Kim TN, Park HJ
- KMID: 2320852
- World J Mens Health.
- 2013 Apr;31(1):31-35.
Currently, phosphodiesterase type 5 (PDE5) inhibitors are the initial treatment option for erectile dysfunction. The reported efficacy of PDE5 inhibitors is about 70%, although it is significantly lower in difficult-to-treat... -
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- A Case of Tadalafil associated Priapism
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Bae JH, Hyun CH, Song PH, Kim HT, Shin HS, Moon KH
- KMID: 2298780
- Korean J Androl.
- 2009 Apr;27(1):59-62.
We report here on a case of priapism that was associated with the use of tadalafil. A 41 year-old-man visited our urology outpatient department with a relapsed erection he'd experienced... -
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- The Effect of Androsterone as the Metabolite of Testosterone to Seizure Suppression
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Kim WJ, Lee SY, Cho KJ, Lee BI
- KMID: 2185030
- J Korean Neurol Assoc.
- 2009 May;27(2):142-146.
BACKGROUND: Androsterone is one of the major metabolites from testosterone whose clinical importance remains unclear. This study evaluated the effects of androsterone on seizure susceptibility in mouse models of epilepsy. METHODS:... -
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- Past, Present and Future of PDE5 Inhibitor
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Kim JJ, Moon DG
- KMID: 2226569
- Korean J Androl.
- 2008 Jun;26(2):49-60.
The phosphodiesterase type-5 inhibitors (PDE5-Is) sildenafil, vardenafil and tadalafil are widely used as first-line therapy for erectile dysfunction (ED). Since the approval of sildenafil in 1998, more than 40 million... -
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- A Case of Acute Pulmonary Thromboembolism after Taking Tadalafil
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Lee J, Kwon JH, Lee CH, Lee SM, Yim JJ, Yoo CG, Kim YW, Han SK, Park YS
- KMID: 2320198
- Tuberc Respir Dis.
- 2012 Oct;73(4):231-233.
Tadalafil is a phosphodiesterase-5 inhibitor (PDE5I), which is widely used to treat erectile dysfunction. Although PDE5Is have excellent safety profiles, and most of the side effects are mild, rare serious... -
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- Open-label, Intermittent Dose, Prospective Study Evaluating the Effects of Tadalafil on Lower Urinary Tract Symptoms and Erectile Function in Patients with Benign Prostatic Hyperplasia: Continuation and Durability of Effects
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Kim TB, Kim KH, Yoon SJ
- KMID: 2232739
- Int Neurourol J.
- 2010 Apr;14(1):7-12.
PURPOSE: Benign prostatic hyperplasia is often accompanied by age-related comorbidity, such as erectile dysfunction (ED). Recent data suggest an association between ED and lower urinary tract symptoms (LUTS), and increasing... -
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- The Effect of Cardiovascular Risk Factors on the Patient with Erectile Dysfunction and Diabetes and the Response to Phosphodiesterase Type 5 Inhibitors
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Sohn DW, Kim SI, Kim SD, Kim DB, Kim JS, Song KH, Kim SW
- KMID: 2298775
- Korean J Androl.
- 2009 Apr;27(1):31-35.
PURPOSE: Erectile dysfunction (ED) is a common comorbidity with diabetes mellitus (DM). The goal of this study was to evaluate the effect of cardiovascular risk factors (CVRF) on ED patients... -
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- Pharmacologic and Complementary and Alternative Medicine Therapies for Irritable Bowel Syndrome
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Chey WD, Maneerattaporn M, Saad R
- KMID: 2284205
- Gut Liver.
- 2011 Sep;5(3):253-266.
Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by episodic abdominal pain or discomfort in association with altered bowel habits (diarrhea and/or constipation). Other gastrointestinal symptoms, such... -
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- Serum High-Sensitivity C-Reactive Protein Levels and Response to 5 mg Tadalafil Once Daily in Patients With Erectile Dysfunction and Diabetes
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Lee JW, Park HJ, Park NC
- KMID: 2315943
- Korean J Urol.
- 2013 Dec;54(12):858-864.
PURPOSE: We studied the relative importance of high-sensitivity C-reactive protein (hs-CRP) concentrations in patients with erectile dysfunction (ED) and diabetes and determined whether the hs-CRP level predicts the response to... -
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- Onset of Action of Phosphodiesterase Type 5 Inhibitors in the Treatment of Erectile Dysfunction
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Son HC, Kim M, Park YH, Jeong CW, Kim HJ, Kim YJ, Huh JS
- KMID: 2226552
- Korean J Androl.
- 2008 Dec;26(4):218-222.
PURPOSE: After the market launch of multiple phosphodiesterase type 5 inhibitors (PDE5Is), a considerable amount of information has emerged regarding the efficacy and the time of initiation of these drugs.... -
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- Efficacy and Safety of Tadalafil 5 mg Administered Once Daily in Korean Men with Erectile Dysfunction: A Prospective, Multicenter Study
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Kang DH, Lee JY, Park SY, Moon HS, Jeong TY, Yoo TK, Choi HY, Park HY, Lee TY, Lee SW
- KMID: 2314630
- Korean J Urol.
- 2010 Sep;51(9):647-652.
PURPOSE: The aim of this study was to evaluate the efficacy of a daily dose of tadalafil 5 mg as well as its safety for the cardiovascular system in men... -
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- Role of Phosphodiesterase Type 5 Inhibitor on Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms
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Kim SD, Park JK
- KMID: 2226462
- Korean J Androl.
- 2011 Aug;29(2):91-100.
- doi: 10.5534/kja.2011.29.2.91
There is strong evidence from multiple epidemiological studies that benign prostate hyperplasia (BPH) induced lower urinary tract symptoms (LUTS) are correlated with erectile dysfunction (ED). Although a direct causal relationship... -
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- Analysis of Prescriptions of Alpha-Blockers and Phosphodiesterase 5 Inhibitors from the Urology Department and Other Departments
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Kang DH, Lee JY, Chung JH, Cho HJ, Cho JM, Moon HS, Kim YT, Yoo TK, Choi HY, Park HY, Lee SW
- KMID: 2232823
- Int Neurourol J.
- 2011 Dec;15(4):216-221.
PURPOSE: We analyzed the prescriptions of alpha-blockers and phosphodiesterase 5 inhibitors (PDE5Is) in the urology department as well as in other departments of the general hospital. METHODS: We investigated the frequency... -
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- Effects of Tadalafil on the Cerebral Ischemia-induced Apoptotic Neuronal Cell Death in Motor Cortex of Gerbils
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Ko IG, Kim SE, Kim DH, Kim TW, Kim BK, Shin MS, Kim CJ, Na YG, Joo KJ, Kim KH
- KMID: 2298799
- Korean J Androl.
- 2010 Apr;28(1):47-56.
PURPOSE: Cerebral ischemia leads to neuronal cell death, and eventually causes neurological impairments. Tadalafil is a long-acting phosphodiesterase type-5 (PDE-5) inhibitor, and it has been used for the treatment of... -
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- Use of Tadalafil for Treating Pulmonary Arterial Hypertension Secondary to Chronic Obstructive Pulmonary Disease
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Kim HS, Park JH, Park SJ, Park JK, Lee HB
- KMID: 1717993
- Korean J Intern Med.
- 2007 Mar;22(1):37-39.
- doi: 10.3904/kjim.2007.22.1.37
Pulmonary arterial hypertension (PAH) secondary to chronic obstructive pulmonary disease (COPD) is incurable and it has an unpredictable survival rate. Two men who suffered from COPD presented with progressive dyspnea... -
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