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Effects of t-butyl hydrogen peroxide on single SR calcium release channels

Shin JH, Kim KH, Suh CK

Using lipid bilayer reconstitution technique, we investigated the oxidation effect of t-butyl hydrogen peroxide (tBHP) on the single channel activity of the sarcoplasmic reticulum (SR) calcium release channels isolated from...
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Effects of Tamoxifen on the Voltage-dependent Ionic Currents in Mouse Colonic Smooth Muscle Cells

Lee DM, Chang SJ, Park CG, Kim MW, Lim GH, Choi S, Yeum CH, Yoon PJ, Jun JY

  • KMID: 772862
  • Korean J Gastroenterol.
  • 2005 Nov;46(5):388-395.
BACKGROUND/AIMS: Tamoxifen is a widely used anticancer drug for breast cancer with frequent gastrointestinal side effects. Changes in gastrointestinal motility is associated with altered activities of membrane ion channels....
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Initiation Site of Ca2+ Entry Evoked by Endoplasmic Reticulum Ca2+ Depletion in Mouse Parotid and Pancreatic Acinar Cells

Jo H, Byun HM, Lee SI, Shin DM

PURPOSE: In non-excitable cells, which include parotid and pancreatic acinar cells, Ca(2+) entry is triggered via a mechanism known as capacitative Ca(2+) entry, or store-operated Ca(2+) entry. This process is...
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Effects of Polyamines on Contractility of Guinea-Pig Gastric Smooth Muscle

Kim YC, Sim JH, Kim YH, Kwon SC, Lee SJ, Kim SR, Kim DW, Park SM, Youn SJ, Lee SJ, Xing DG, Xu WX, Kim KW

This study was designed to investigate the effects of polyamines on mechanical contraction and voltage-dependent calcium current (VDCC) of guinea-pig gastric smooth muscle. Mechanical contraction and calcium channel current (I(Ba))...
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Fluoxetine inhibits L-type Ca2+ and transient outward K+ currents in rat ventricular myocytes

Park KS, Kong ID, Park KC, Lee JW

The most common cardiovascular side effects of antidepressants are cardiac arrhythmias and orthostatic hypotension. Little is known, however, about the mechanisms by which these adverse reactions may occur,...
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Inhibitory Effect of Angiotensin II Receptor Antagonist on the Contraction and Growth of Hepatic Stellate Cells

Baik SK, Jo HS, Suk KT, Kim JM, Lee BJ, Choi YJ, Kim HS, Lee DK, Kwon SO, Lee KI, Cha SK, Park KS, Kong ID

  • KMID: 772535
  • Korean J Gastroenterol.
  • 2003 Aug;42(2):134-141.
BACKGROUNDS/AIMS: This study aimed to investigate the effects of angiotensin II (ANG II) and its receptor antagonist (losartan) on the contraction and growth of HSCs. METHODS: HSCs were isolated...
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