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Effects of Drugs on the Interaction of Calcium and Cardiac Muscle Memberane Fragments

Kang DH, Lee JW, Chung KS

The effect of drugs on calcium-binding to cardiac muscle membrane fragments and its turnover rate was studied. Ouabian, acetylcholine, isoproterenol and norepinephrine did not have any effect either on calcium-binding...
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Effects of Dantrolene on the Interaction of Calcium and Erythrocyte Membrane

Kang BS

Dantrolene sodium in vitro inhibited the ATP-dependent efflux of calcium from human Fed cells, the Ca++-ATPase activity of red blood cell membrane fragments (RBCMF) and passive calcium binding to RBCMF....
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Calcium-dependent and -independent mechanisms of P2Y receptor regulated anion secretion in polarized epithelia

Wong HY, Ko WH

No abstract available.
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A model for the reaction mechanism of the transglutaminase 3 enzyme

Ahvazi B, Steinert P

  • KMID: 1109310
  • Exp Mol Med.
  • 2003 Aug;35(4):228-242.
Transglutaminase enzymes (TGases) catalyze the calcium dependent formation of an isopeptide bond between protein-bound glutamine and lysine substrates. Previously we have shown that activated TGase 3 acquires two additional calcium...
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Vitamin D Activities for Health Outcomes

Morris HA

Reports describing significant health risks due to inadequate vitamin D status continue to generate considerable interest amongst the medical and lay communities alike. Recent research on the various molecular activities...
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Further Studies on Effects of Some Local Anesthetics on Calcium Binding to Lipid-extracted RBC Membrane Fragments: Effect of Modification of Carboxyl Group with Carbodiimide

Hah JS, Kang DH

The interaction of calcium and local anesthetics was investigated with the lipid extracted human RBC membrane fragments treated with carbodiimide in order to titrate carboxyl groups. A water soluble carbodiimide...
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Effect of Hydrocortisone Succinate on Ca45 Resorption and Incorporation in Bone Culture of Rat

Cho MY, Choi CD, Kim JH

  • KMID: 2439773
  • Yonsei Med J.
  • 1973 Dec;14(1):44-48.
Ca45 resorption and incoporration into albino rat-bones in tissue culture was considered in studying the pathogenesis of osteoporosiscaused by cotinued administration of glucocorticoid, hydrocortisone succinate. 18-day old tibias were cultured...
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Phosphorus and Calcium Homeostasis in Chronic Subtotally Nephrectomized Parathyroidectomized Rats

Han DS, Bank N

Calcium and phosphorus balance studies were carried out in subtotally nephrectomized rats (NX), with or without parathyroidectomy (NX-PTX; NX sham-PTX) in order to determine the ability of the remnant kidney...
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Calcium Uptake and Release through Sarcoplasmic Reticulum in the Inferior Oblique Muscles of Patients with Inferior Oblique Overaction

Kim HS, Chang YH, Kim DH, Park SR, Han SH, Lee JB

We characterized and compared the characteristics of Ca2+ movements through the sarcoplasmic reticulum of inferior oblique muscles in the various conditions including primary inferior oblique overaction (IOOA), secondary IOOA, and...
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The metabolic effects of estriol in female rat liver

Yang JM, Kim SS, Kim JI, Ahn BM, Choi SW, Kim JK, Lee CD, Chung KW, Sun HS, Park DH, Thurman RG

The effects of estriol on oxygen uptake, glucose release, lactate and pyruvate production, beta-hydroxybutyrate and acetoacetate production in perfused rat liver as well as, carbon uptake in rat liver and...
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The extracellular calcium sensing receptor is expressed in mouse mesangial cells and modulates cell proliferation

Kwak JO, Kwak J, Kim HW, Oh KJ, Kim YT, Jung SM, Cha SH

  • KMID: 1089455
  • Exp Mol Med.
  • 2005 Oct;37(5):457-465.
The extracellular calcium sensing receptor (CaSR) belongs to the type III family of G-protein-coupled receptors, a family that comprises the metabotropic glutamate receptor and the putative vomeronasal organ receptors. The...
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Tyrosine phosphatase and cytochrome P450 activity are critical in regulating store-operated calcium channels in human fibroblasts

Lee KM

  • KMID: 1115949
  • Exp Mol Med.
  • 2006 Dec;38(6):703-717.
Diverse signaling pathways have been proposed to regulate store-operated calcium entry (SOCE) in a wide variety of cell types. However, it still needs to be determined if all of these...
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TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts

Woo JS, Cho CH, Kim DH, Lee EH

During membrane depolarization associated with skeletal excitation-contraction (EC) coupling, dihydropyridine receptor [DHPR, a L-type Ca2+ channel in the transverse (t)-tubule membrane] undergoes conformational changes that are transmitted to ryanodine receptor...
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Caffeine causes glycerophosphorylcholine accumulation through ryanodine-inhibitable increase of cellular calcium and activation of phospholipase A2 in cultured MDCK cells

Kim DK, Jung KY

  • KMID: 1109298
  • Exp Mol Med.
  • 1998 Sep;30(3):151-158.
Glycerophosphrylocholine (GPC) is a renal medullary compatible organic osmolyte that is derived from choline via phosphatidylcholine, which is catalyzed in part by phospholipase A2 (PLA2) and its degradation by GPC: choline phosphodiesterase (GPC:...
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Changes in biochemical bone markers during pregnancy and puerperium

Yoon BK, Lee JW, Choi DS, Roh CR, Lee JH

To elucidate the changes in bone turnover during pregnancy and puerperium, we measured serially the levels of serum osteocalcin and urine deoxypyridinoline (Dpy) as markers of bone formation and bone...
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The synthetic peptide, His-Phe-Tyr-Leu-Pro-Met, is a chemoattractant for Jukat T cells

Kim YD, Bae YS, Park JC, Suh PG, Ryu SH

  • KMID: 1457539
  • Exp Mol Med.
  • 2001 Dec;33(4):257-262.
His-Phe-Tyr-Leu-Pro-Met (HFYLPM) is a synthetic peptide that stimulates Jurkat T cells resulting in intracellular calcium ([Ca2+]i) increase in a pertussis toxin (PTX)-sensitive manner. We have examined the physiological role of...
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Protease activity of 80 kDa protein secreted from the apicomplexan parasite Toxoplasma gondii

Song KJ, Nam HW

This study describes the characterization of 80 kDa protease showing gelationlytic property among three proteases in the excretory/secretory proteins (ESP) from Toxoplasma gondii. The protease activity was detected in the...
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Bone Mineral Density, Biochemical Bone Turnover Markers and Factors associated with Bone Health in Young Korean Women

Park YJ, Lee SJ, Shin NM, Shin H, Kim YK, Cho Y, Jeon S, Cho I

PURPOSE: This study was done to assess the bone mineral density (BMD), biochemical bone turnover markers (BTMs), and factors associated with bone health in young Korean women. METHODS: Participants were 1,298...
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Effects of Vitamin K2 on the Development of Osteopenia in Rats as the Models of Osteoporosis

Iwamoto J, Takeda T, Sato Y

Vitamin K2 is widely used for the treatment of osteoporosis in Japan. To understand the effects of vitamin K2 on bone mass and bone metabolism, we reviewed its effects on...
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The Role of Endothelin Receptor A during Myelination of Developing Oligodendrocytes

Jung KJ, Kim DW, Lee HN, Lee YS, Lee SJ, Che JH, Lee YH, Kang BC

Endothelin (ET)-1 and its receptors (ETA and ETB receptor) are present in the central nervous system. ET exerts biological effects on gliogenesis and glial cell functions. In order to define...
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