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Role of Caffeic Acid on Collagen Production in Nasal Polyp-Derived Fibroblasts

Chung SW, Park IH, Hong SM, Cho JS, Moon JH, Kim TH, Lee HM

OBJECTIVES: Caffeic acids are known to have anti-oxidant, anti-inflammatory, immunomodulatory, and tissue reparative effects. The purposes of this study were to determine the effect of caffeic acid on transforming growth...
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The Effect of Caffeic Acid on Wound Healing in Skin-incised Mice

Song HS, Park TW, Sohn UD, Shin YK, Choi BC, Kim CJ, Sim SS

This study was carried out to investigate the wound healing effect of caffeic acid in skin-incised mice. Caffeic acid showed significant effects on anti-inflammatory activity and wound healing, such as...
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Effect of Caffeic Acid Phenethyl Ester on Lipopolysaccharide-induced Murine Macrophage Activation

Lee SH, Li M, Lee DW, Lim DY, Jeong CW, Kwak SH

BACKGROUND: Caffeic acid phenethyl ester (CAPE) is an active component of propolis and is known to have anti-inflammatory properties. This study was performed to evaluate the effects of CAPE on...
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3,4,5-Trihydroxycinnamic Acid Inhibits LPS-Induced iNOS Expression by Suppressing NF-kappaB Activation in BV2 Microglial Cells

Lee JW, Bae CJ, Choi YJ, Kim SI, Kim NH, Lee HJ, Kim SS, Kwon YS, Chun W

Although various derivatives of caffeic acid have been reported to possess a wide variety of biological activities such as neuronal protection against excitotoxicity and anti-inflammatory property, the biological activity of...
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Mechanism of vasodilation by propofol in the rabbit renal artery

Park SY, Jung I, Kwon SC

  • KMID: 2263234
  • Anesth Pain Med.
  • 2011 Oct;6(4):336-341.
BACKGROUND: Propofol directly inhibits vascular reactivity. However, available information regarding the underlying mechanisms of propofol is poor. Therefore, mechanisms of the underlying relaxant action of propofol were investigated using rabbit...
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Anti-inflammatory Activity of 1-docosanoyl Cafferate Isolated from Rhus verniciflua in LPS-stimulated BV2 Microglial Cells

Lee JW, Cheong IY, Kim HS, Lee JJ, Lee YS, Kwon YS, Kim MJ, Lee HJ, Kim SS, Chun W

  • KMID: 2389103
  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):9-15.
Although various derivatives of caffeic acid have been reported to possess a wide variety of biological activities such as protection of neuronal cells against excitotoxicity, the biological activity of 1-docosanoyl...
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Cytotoxic Effects of Lysophosphatidylcholine on Vascular Smooth Muscle Cells

Lee DY, Kang YH, Choi DS, Lee YJ, Rhyu MR, Yoon BK

  • KMID: 2321326
  • J Korean Soc Menopause.
  • 2012 Dec;18(3):139-146.
OBJECTIVES: To investigate the cytotoxic effects of lysophosphatidylcholine (lysoPC), an active component of oxidized low-density lipoproteins (LDL), on vascular smooth muscle cells (VSMCs). METHODS: VSMCs were derived from rat aorta. Cell...
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Activation of NF-κB and AP-1 Mediates Hyperproliferation by Inducing β-Catenin and c-Myc in Helicobacter pylori-Infected Gastric Epithelial Cells

Byun E, Park B, Lim JW, Kim H

PURPOSE: In the gastric mucosa of Helicobacter pylori (H. pylori)-infected patients with gastritis or adenocarcinoma, proliferation of gastric epithelial cells is increased. Hyperproliferation is related to induction of oncogenes, such...
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Impact of Lysophosphatidylcholine on the Plasminogen Activator System in Cultured Vascular Smooth Muscle Cells

Yoon BK, Kang YH, Oh WJ, Park K, Lee DY, Choi D, Kim DK, Lee Y, Rhyu MR

The balance between tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) regulates fibrinolysis. PAI-1 expression increases in atherosclerotic arteries and vascular smooth muscle cells (VSMCs) are one...
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The effect of ferulic acid ethyl ester on leptin-induced proliferation and migration of aortic smooth muscle cells

Tsai YC, Lee YM, Hsu CH, Leu SY, Chiang HY, Yen MH, Cheng PY

Leptin is a peptide hormone, which has a central role in the regulation of body weight; it also exerts many potentially atherogenic effects. Ferulic acid ethyl ester (FAEE) has been...
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