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Prostaglandin E2 and Interleukin-1beta Reduce E-cadherin Expression by Enhancing Snail Expression in Gastric Cancer Cells

Jee YS, Jang TJ, Jung KH

Inflammation is closely related to the progression of cancer as well as tumorigenesis. Here, we investigated the effect of prostaglandin E2 (PGE2) and interleukin-1beta (IL-1beta) on E-cadherin expression in SNU719...
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Epstein-Barr Virus, Beta-Catenin, and E-cadherin in Gastric Carcinomas

Jung IM, Chung JK, Kim YA, Kim JE, Heo SC, Ahn YJ, Hwang KT, Kim BG, Lee KL, Kim CW, Kim WH, Chang MS

Activated beta-catenin is suggested to inhibit NF-kappaB activation, and we previously demonstrated that NF-kappaB nuclear positivity was more frequent in Epstein-Barr virus (EBV)-infected gastric carcinomas. It is controversial that beta-catenin...
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Immunoexpression of HBME-1, High Molecular Weight Cytokeratin, Cytokeratin 19, Thyroid Transcription Factor-1, and E-cadherin in Thyroid Carcinomas

Choi YL, Kim MK, Suh JW, Han J, Kim JH, Yang JH, Nam SJ

To examine the immunohistochemical alterations associated with the histological dedifferentiation of thyroid carcinomas, we performed staining for HBME-1, high molecular weight cytokeratin (HCK), CK 19, thyroid transcription factor-1 (TTF-1) and...
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E-cadherin and Cytokeratin Subtype Profiling in Effusion Cytology

Han J, Kim MK, Nam SJ, Yang JH

Diagnostic utility of E-cadherin (E-CD) and cytokeratin (CK) subtype profiling in effusion cytology was investigated, employing immunocytochemistry on cellblock sections available from 211 metastatic carcinomas (MC), 6 mesotheliomas and 73...
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Expression of Beta-catenin and E-cadherin in Early Gastric Cancer: Correlation with Clinicopathologic Parameters

Song BJ, Park YJ, Kim HS, Kim CN, Chang SH

  • KMID: 772610
  • Korean J Gastroenterol.
  • 2004 Feb;43(2):82-89.
BACKGROUND/AIMS: Beta-catenin is known to perform two unrelated functions in cadherin-mediated cell to cell adhesion system and Wnt pathway. Recent studies reported cytoplasmic and nuclear accumulation of beta-catenin by...
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Expression Patterns of E-cadherin and beta-catenin According to Clinicopathological Characteristics of Hepatocellular Carcinoma

Bae SH, Jung ES, Park YM, Jang JW, Choi JY, Cho SH, Yoon SK, Ahn BM, Cha SB, Chung KW, Sun HS, Park DH, Kim BK, Kim DG

  • KMID: 863100
  • Korean J Hepatol.
  • 2002 Sep;8(3):297-303.
BACKGROUND/AIMS: E-cadherin is involved in intercellular binding and cellular polarity formation. beta-catenin plays a fundamental role in regulation of the E-cadherin cell adhesion complex. The abnormalities of the components...
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The Expression of E-cadherin in Human and Rat Hepatic Stellate Cells: Evidence of Epithelial-Mesenchymal Transition

Lim YS, Lee HS

  • KMID: 863072
  • Korean J Hepatol.
  • 2002 Mar;8(1):90-99.
BACKGROUND/AIMS: The embryonal origin of hepatic stellate cells (HSCs), the principal cells in hepatic fibrogenesis, is still intriguing. We have previously demonstrated that human HSCs express cytokeratins which suggests...
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