- IL-4 and IL-5 Secretions Predominate in the Airways of Wistar Rats Exposed to Toluene Diisocyanate Vapor
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Kouadio K, Zheng KC, Toure AA, Dosso M, Todoriki H
- KMID: 1791969
- J Prev Med Public Health.
- 2014 Jan;47(1):57-63.
OBJECTIVES: We established a Wistar rat model of asthma caused by toluene diisocyanate (TDI) exposure, and investigated the relationship between TDI exposure concentrations and respiratory hypersensitivity, airway inflammation, and cytokine... -
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- Alveolar macrophages modulate allergic inflammation in a murine model of asthma
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Bang BR, Chun E, Shim EJ, Lee HS, Lee SY, Cho SH, Min KU, Kim YY, Park HW
- KMID: 1009966
- Exp Mol Med.
- 2011 May;43(5):275-280.
- doi: 10.3858/emm.2011.43.5.028
The role of alveolar macrophages (AMs) in the pathogenesis of asthma is still unknown. The aim of the present study was to investigate the effects of AM in the murine... -
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- Are pulmonary hemostasis and fibrinolysis out of balance in equine chronic pneumopathies?
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Barton AK, Wirth C, Bondzio A, Einspanier R, Gehlen H
- KMID: 2412453
- J Vet Sci.
- 2017 Sep;18(3):349-357.
- doi: 10.4142/jvs.2017.18.3.349
Clinical examination, bronchoalveolar lavage fluid (BALF) cytology, acute-phase protein, and pulmonary hemostasis and fibrinolysis marker (fibrinogen, serum amyloid A [SAA], and D-dimer) results were compared between control and respiratory disease-affected... -
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- The effects of pycnogenol on antioxidant enzymes in a mouse model of ozone exposure
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Lee MS, Moon KY, Bae DJ, Park MK, Jang AS
- KMID: 1501777
- Korean J Intern Med.
- 2013 Mar;28(2):216-223.
- doi: 10.3904/kjim.2013.28.2.216
BACKGROUND/AIMS: Ozone is an environmentally reactive oxidant, and pycnogenol is a mixture of flavonoid compounds extracted from pine tree bark that have antioxidant activity. We investigated the effects of pycnogenol... -
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- Metformin Reduces Bleomycin-induced Pulmonary Fibrosis in Mice
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Choi SM, Jang AH, Kim H, Lee KH, Kim YW
- KMID: 2468274
- J Korean Med Sci.
- 2016 Sep;31(9):1419-1425.
- doi: 10.3346/jkms.2016.31.9.1419
Metformin has anti-inflammatory and anti-fibrotic effects. We investigated whether metformin has an inhibitory effect on bleomycin (BLM)-induced pulmonary fibrosis in a murine model. A total of 62 mice were divided... -
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- Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis
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Song JS, Kang CM, Kang HH, Yoon HK, Kim YK, Kim KH, Moon HS, Park SH
- KMID: 1078362
- Exp Mol Med.
- 2010 Jun;42(6):465-476.
- doi: 10.3858/emm.2010.42.6.048
CXC chemokine receptor 4 (CXCR4), which binds the stromal cell-derived factor-1 (SDF-1), has been shown to play a critical role in mobilizing the bone marrow (BM)-derived stem cells and inflammatory... -
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- Effects of Diet-Induced Mild Obesity on Airway Hyperreactivity and Lung Inflammation in Mice
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Jung SH, Kwon JM, Shim JW, Kim DS, Jung HL, Park MS, Park SH, Lee J, Lee WY, Shim JY
- KMID: 1798140
- Yonsei Med J.
- 2013 Nov;54(6):1430-1437.
- doi: 10.3349/ymj.2013.54.6.1430
PURPOSE: Obesity has been suggested to be linked to asthma. However, it is not yet known whether obesity directly leads to airway hyperreactivity (AHR) or obesity-induced airway inflammation associated with... -
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- Proteomic differences with and without ozone-exposure in a smoking-induced emphysema lung model
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Uh ST, Koo SM, Jang AS, Park SW, Choi JS, Kim YH, Park CS
- KMID: 2129665
- Korean J Intern Med.
- 2015 Jan;30(1):62-72.
- doi: 10.3904/kjim.2015.30.1.62
BACKGROUND/AIMS: Acute exacerbations in chronic obstructive pulmonary disease may be related to air pollution, of which ozone is an important constituent. In this study, we investigated the protein profiles associated... -
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- An antioxidant modulates expression of receptor activator of NF-kappaB in asthma
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Lee KS, Park HS, Park SJ, Kim SR, Min KH, Jin SM, Li L, Lee YC
- KMID: 1094147
- Exp Mol Med.
- 2006 Jun;38(3):217-229.
Oxidative stress plays critical roles in airway inflammation that is usually accompanied by increased vascular permeability and plasma exudation. VEGF increases vascular permeability and leads to airway inflammation. In addition,... -
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