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Revisiting the Role of Surgical Resection for Brain Metastasis

Byun J, Kim JH

Brain metastasis (BM) is the most common type of brain tumor in adults. The contemporary management of BM remains challenging. Advancements in systemic cancer treatment have increased the survival of...
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Advances in Brain Metastasis Models

Lee JE, Yang SH

To obtain achievements in addressing the clinical challenges of brain metastasis, we need a clear understanding of its biological mechanisms. Brain metastasis research is challenged by many practical scientific barriers....
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The Role of Hypoxia in Brain Tumor Immune Responses

Park JH, Lee HK

Oxygen is a vital component of living cells. Low levels of oxygen in body tissues, known as hypoxia, can affect multiple cellular functions across a variety of cell types and...
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Breast Cancer to Meningioma: A Rare Case of Tumor-to-Tumor Metastasis

Joe WH, Lee CY, Kim CH, Ko YS, Kim SP, Kwon SM

Tumor-to-tumor metastasis (TTM) is defined as the hematogenous metastasis within a primary host tumor from a donor neoplasm. Since there is insufficient evidence regarding the pathophysiology, clinical course, and management...
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Medulloblastoma: Current Perspectives and Recent Advances

Choi JY

Medulloblastoma is the most common embryonal tumor of the central nervous system in childhood. Combined multimodality approaches, including surgery, radiation, and chemotherapy, have improved the outcome of medulloblastoma. Advances in genomic...
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Role of Radiotherapy in Patients With Relapsed Medulloblastoma

Lim DH

During the last three decades, the management of medulloblastoma (MBL) has made enormous progress with a multidisciplinary approach, incorporating surgery, radiotherapy (RT), and chemotherapy. Despite this improvement, 20%–30% of patients...
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Brain Invasion and Trends in Molecular Research on Meningioma

Go KO, Kim YZ

Meningiomas are the most common primary brain tumors in adults. The treatment of non-benign meningiomas remains a challenging task, and after the publication of the 2021 World Health Organization classification,...
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Molecular Biology of Brain Metastases

Gwak HS

Brain metastases (BMs) often occur in patients with lung cancer, breast cancer, and melanoma and are the leading cause of morbidity and mortality. The incidence of BM has increased with...
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A Rare Occurrence of Primarily Extranodal Spinal Epidural Lymphoma With Spinal Cord Compression and Invasion to the Thoracic Cavity

Seok MC, Madadi AK, Mosleh MM, Chang SH, Sohn MJ

A 41-year-old man suffered from progressive radiculomyelopathy caused by spinal epidural mass primarily encasing the spinal cord at the cervicothoracic vertebrae that extended into the thoracic cavity through the neural...
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MRI-Based Classification of Rathke’s Cleft Cyst and Its Clinical Implication

Kim G, Moon JH, Kim SH, Kim EH

Background Rathke’s cleft cysts (RCCs) are benign tumors of the pituitary gland. Small, asymptomatic RCCs do not require surgical treatment, whereas surgical treatment is required for symptomatic RCCs. Methods We retrospectively...
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