- A case of central pontine and extrapontine myelinolysis with early hypermetabolism on 18FDG-PET scan
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Roh JK, Nam H, Lee MC
- KMID: 1107236
- J Korean Med Sci.
- 1998 Feb;13(1):99-102.
- doi: 10.3346/jkms.1998.13.1.99
We report a 63 year-old woman who developed central pontine and extrapontine myelinolysis after rapid correction of hyponatremia. Lesions on brain MRI showed hypermetabolism on 18FDG-PET scan in the early... -
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- Statistical Mapping Analysis of Brain Metabolism in Patients with Subcortical Aphasia after Intracerebral Hemorrhage: A Pilot Study of F-18 FDG PET Images
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Kim YW, Kim HS, An YS
- KMID: 1779685
- Yonsei Med J.
- 2012 Jan;53(1):43-52.
- doi: 10.3349/ymj.2012.53.1.43
PURPOSE: This study was aimed to evaluate the brain metabolism in patients with subcortical aphasia after intracerebral hemorrhage (ICH) and the relationship between the severity of aphasia and regional brain... -
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- The proteins of synaptic vesicle membranes are affected during ageing of rat brain
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Lee SR, Kim AR, Kim JS, Kim JB, Lee JY, Lee YL, Choe M, Park JB
- KMID: 1457533
- Exp Mol Med.
- 2001 Dec;33(4):220-225.
Low molecular weight GTP-binding proteins are molecular switches that are believed to play pivotal roles in cell growth, differentiation, cytoskeletal organization, and vesicular trafficking. Rab proteins are key players in... -
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- Transient improvement of pyruvate metabolism after coenzyme Q therapy in Kearns-Sayre syndrome: MRS study
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Choi C, Sunwoo IN, Kim HS, Kim DI
- KMID: 1062251
- Yonsei Med J.
- 2000 Oct;41(5):676-679.
- doi: 10.3349/ymj.2000.41.5.676
Coenzyme Q therapy has been used to support metabolic derangements in patients with mitochondrial encephalomyopathies. Biochemical analysis of the living human brain can be performed by magnetic resonance spectroscopy (MRS).... -
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- Effects of MK-801 (dizocilpine) on Brain Cell Membrane Function and Energy Metabolism in Experimental Escherichia coli Meningitis in the Newborn Piglet
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Ko SY, Shim JW, Kim SS, Kim MJ, Chang YS, Park WS, Shin SM, Lee MH
- KMID: 2157628
- J Korean Med Sci.
- 2003 Apr;18(2):236-241.
- doi: 10.3346/jkms.2003.18.2.236
We evaluated the efficacy of non-competitive N-methyl-D-aspartate receptor antagonist MK-801 (dizocilpine) as an adjuvant therapy in experimental neonal bacterial meningitis. Meningitis was induced by injecting 10(6) colony forming units of... -
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- Studies of Hepatic, Brain Monoamine Oxidase and Brain Serotonin in Rats
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Chai KJ, Kim YS
- KMID: 692972
- Yonsei Med J.
- 1984 Jun;25(1):27-38.
- doi: 10.3349/ymj.1984.25.1.27
The effects of 7-ethyl-8-methylf1avin (7-Et) and 7-methyl-8-ethyl-flavin (8-Et) on rat hepatic monoamine oxidase (MAO), brain MAO activity and 5-hydroxytryptamine (5-HT or serotonin) in rat brain were investigated. In the study... -
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- Regulation of GTP-binding state in RalA through Ca2+ and calmodulin
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Park JB
- KMID: 755118
- Exp Mol Med.
- 2001 Mar;33(1):54-58.
RalA GTPase, a member of Ras superfamily proteins, shows alternative forms between the active GTP-binding and the inactive GDP-binding states. Ral-specific guanine nucleotide exchange factor such as RalGDS interacts with... -
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- Upregulation of VEGF and FGF2 in Normal Rat Brain after Experimental Intraoperative Radiation Therapy
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Kim JH, Chung YG, Kim CY, Kim HK, Lee HK
- KMID: 1778573
- J Korean Med Sci.
- 2004 Dec;19(6):879-886.
- doi: 10.3346/jkms.2004.19.6.879
The expression of vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF)2 in the irradiated brain was examined to test how a single high dose radiation, similar to that... -
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- Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing
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Kang MJ, Chung YH, Hwang CI, Murata M, Fujimoto T, Mook-Jung , Cha CI, Park WY
- KMID: 1111405
- Exp Mol Med.
- 2006 Apr;38(2):126-133.
Lipid rafts provide a platform for regulating cellular functions and participate in the pathogenesis of several diseases. However, the role of caveolin-1 in this process has not been elucidated definitely... -
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- Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome
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Kim B, Feldman EL
- KMID: 2155414
- Exp Mol Med.
- 2015 Mar;47(3):e149.
- doi: 10.1038/emm.2015.3
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that includes obesity, diabetes, and dyslipidemia. Accumulating evidence implies that MetS contributes to the development and progression of Alzheimer's disease... -
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- Pathology of non-thermal irreversible electroporation (N-TIRE)-induced ablation of the canine brain
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Rossmeisl , Garcia PA, Roberston , Ellis TL, Davalos RV
- KMID: 1712310
- J Vet Sci.
- 2013 Dec;14(4):433-440.
- doi: 10.4142/jvs.2013.14.4.433
This study describes the neuropathologic features of normal canine brain ablated with non-thermal irreversible electroporation (N-TIRE). The parietal cerebral cortices of four dogs were treated with N-TIRE using a dose-escalation... -
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- Protective Effect of Hypoxic Preconditioning on Hypoxic-Ischemic Injured Newborn Rats
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Park HK, Seol IJ, Kim KS
- KMID: 1123451
- J Korean Med Sci.
- 2011 Nov;26(11):1495-1500.
- doi: 10.3346/jkms.2011.26.11.1495
Brief episodes of cerebral hypoxia-ischemia cause transient ischemic tolerance to subsequent ischemic events that are otherwise lethal. This study was conducted to evaluate the protective effect of hypoxic preconditioning on... -
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- Cell-free expression and functional reconstitution of CALM in clathrin assembly
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Kim JA, Kim HL
- KMID: 1085745
- Exp Mol Med.
- 2001 Jun;33(2):89-94.
Clathrin-mediated vesicle formation is an essential step in the intracellular trafficking of the protein and lipid. Binding of clathrin assembly protein to clathrin triskelia induces their assembly into clathrin-coated vesicles... -
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- Diffusion-weighted image and MR spectroscopic analysis of a case of MELAS with repeated attacks
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Kim HS, Kim DI, Lee BI, Jeong EK, Choi C, Lee JD, Yoon PH, Kim EJ, Kim SH, Yoon YK
- KMID: 720596
- Yonsei Med J.
- 2001 Feb;42(1):128-133.
- doi: 10.3349/ymj.2001.42.1.128
We report the clinical and MR manifestations of an 18 year-old girl with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome. Recurrent status epilepticus caused... -
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- Diverse Molecular Targets for Therapeutic Strategies in Alzheimer's Disease
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Han SH, Mook-Jung
- KMID: 1789947
- J Korean Med Sci.
- 2014 Jul;29(7):893-902.
- doi: 10.3346/jkms.2014.29.7.893
Alzheimer's disease (AD) is the most common form of dementia caused by neurodegenerative process and is tightly related to amyloid beta (Abeta) and neurofibrillary tangles. The lack of early diagnostic... -
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- Gene Expression Profiles in Genetically Different Mice Infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU
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Ismail HA, Quan JH, Wei Z, Choi IW, Cha GH, Shin DW, Lee YH, Song CJ
- KMID: 1364889
- Korean J Parasitol.
- 2012 Mar;50(1):7-13.
- doi: 10.3347/kjp.2012.50.1.7
Toxoplasma gondii can modulate host cell gene expression; however, determining gene expression levels in intermediate hosts after T. gondii infection is not known much. We selected 5 genes (ALDH1A2, BEX2,... -
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- Primary Central Nervous System ALK Positive Anaplastic Large Cell Lymphoma with Predominantly Leptomeningeal Involvement in an Adult
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Park JS, Park H, Park S, Kim SJ, Seol HJ, Ko YH
- KMID: 1727900
- Yonsei Med J.
- 2013 May;54(3):791-796.
- doi: 10.3349/ymj.2013.54.3.791
A 31-year-old Korean male presented with altered consciousness and severe headache. Brain MRI delineated focal leptomeningeal enhancement without any intracerebral lesions. Diagnosis was made based on a brain biopsy showing... -
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- Quantitative in Vivo Detection of Brain Cell Death after Hypoxia Ischemia Using the Lipid Peak at 1.3 ppm of Proton Magnetic Resonance Spectroscopy in Neonatal Rats
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Ahn SY, Yoo HS, Lee JH, Sung DK, Jung YJ, Sung SI, Lim KH, Chang YS, Lee JH, Kim KS, Park WS
- KMID: 1777505
- J Korean Med Sci.
- 2013 Jul;28(7):1071-1076.
- doi: 10.3346/jkms.2013.28.7.1071
This study was performed to determine the accuracy of proton magnetic spectroscopy (1H-MRS) lipid peak as a noninvasive tool for quantitative in vivo detection of brain cell death. Seven day-old... -
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- Cerebral vasoreactivity by transcranial Doppler in carbon disulfide poisoning cases in Korea
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Lee E, Kim MH
- KMID: 1038446
- J Korean Med Sci.
- 1998 Dec;13(6):645-651.
- doi: 10.3346/jkms.1998.13.6.645
The abnormalities of cerebral vasoreactivity were evaluated in CS2 poisoning cases. In 34 retired workers with CS2 poisoning (case group) and 20 healthy individuals (control group), blood flow velocities... -
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- Production and characterization of monoclonal antibodies against amphiphysins
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Jin YL, Kim KY, Soung NK, Shin EY, Kim EG, Kim SR
- KMID: 1085742
- Exp Mol Med.
- 2001 Jun;33(2):69-75.
Amphiphysin I and II, proteins enriched in nerve terminals, form heterodimers and interact with dynamin and synaptojanin through their Src homology 3 (SH3) domain. In order to study the expression... -
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