- The effects of laminin on the characteristics and differentiation of neuronal cells from epidermal growth factor-responsive neuroepithelial cells
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Park DS, Park JS, Yeon DS
- KMID: 711537
- Yonsei Med J.
- 1998 Apr;39(2):130-140.
- doi: 10.3349/ymj.1998.39.2.130
Many extracellular matrix molecules are expressed in the embryonic nervous system and there is some evidence that they are important regulators of neural development. Of these molecules, laminin appears to... -
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- Neural toxicity induced by accidental intrathecal vincristine administration
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Kwack EK, Kim DJ, Park TI, Cho KR, Kwon IH, Sohn YK
- KMID: 646050
- J Korean Med Sci.
- 1999 Dec;14(6):688-692.
- doi: 10.3346/jkms.1999.14.6.688
Described here is a case of accidental intrathecal administration of vincristine with pathologic findings in the central nervous system. A 3-year-old boy with acute lymphoblastic leukemia, was given his ninth... -
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- Effects of MK-801 (dizocilpine) on Brain Cell Membrane Function and Energy Metabolism in Experimental Escherichia coli Meningitis in the Newborn Piglet
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Ko SY, Shim JW, Kim SS, Kim MJ, Chang YS, Park WS, Shin SM, Lee MH
- KMID: 2157628
- J Korean Med Sci.
- 2003 Apr;18(2):236-241.
- doi: 10.3346/jkms.2003.18.2.236
We evaluated the efficacy of non-competitive N-methyl-D-aspartate receptor antagonist MK-801 (dizocilpine) as an adjuvant therapy in experimental neonal bacterial meningitis. Meningitis was induced by injecting 10(6) colony forming units of... -
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- The effect of early versus late onset of temporal lobe epilepsy on hemispheric memory laterality: an intracarotid amobarbital procedure study
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Kim H, Yi S
- KMID: 645119
- J Korean Med Sci.
- 1997 Dec;12(6):559-563.
- doi: 10.3346/jkms.1997.12.6.559
Thirty-three temporal lobe epilepsy (TLE) patients, 19 left TLE and 14 right TLE, underwent an intracarotid amobarbital procedure. For each patient, hemispheric memory laterality was determined by measuring the... -
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- Neuropharmacological effects of deltamethrin in rats
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Manna S, Bhattacharyya D, Mandal TK, Dey S
- KMID: 1059198
- J Vet Sci.
- 2006 Jun;7(2):133-136.
- doi: 10.4142/jvs.2006.7.2.133
This study examined the effect of deltamethrin on some of the neuropharmacological paradigms in a rat brain such as the motor co-ordination test using a rotarod, the pentobarbitone-induced sleeping time and pentylenetetrazole (PTZ)-induced convulsion... -
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- Transient improvement of pyruvate metabolism after coenzyme Q therapy in Kearns-Sayre syndrome: MRS study
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Choi C, Sunwoo IN, Kim HS, Kim DI
- KMID: 1062251
- Yonsei Med J.
- 2000 Oct;41(5):676-679.
- doi: 10.3349/ymj.2000.41.5.676
Coenzyme Q therapy has been used to support metabolic derangements in patients with mitochondrial encephalomyopathies. Biochemical analysis of the living human brain can be performed by magnetic resonance spectroscopy (MRS).... -
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- Temozolomide Chemotherapy in Patients with Recurrent Malignant Gliomas
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Yang SH, Kim MK, Lee TK, Lee KS, Jeun SS, Park CK, Kang JK, Kim MC, Hong YK
- KMID: 2157831
- J Korean Med Sci.
- 2006 Aug;21(4):739-744.
- doi: 10.3346/jkms.2006.21.4.739
Numerous studies have demonstrated the clinical activity of temozolomide, a second-generation alkylating agent, against malignant brain tumors, however, its activity has not been reported in an Asian population. This study... -
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- Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy
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Kim CY, Park SH, Jeong M, Kwon OS, Doh H, Kang SH, Robbins PD, Kim BM, Seol DW, Kim BG
- KMID: 1123370
- Exp Mol Med.
- 2011 Oct;43(10):580-586.
- doi: 10.3858/emm.2011.43.10.065
Malignant glioma is the most frequent type in brain tumors. The prognosis of this tumor has not been significantly improved for the past decades and the average survival of patients... -
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- Metoclopramide protection of diazinon-induced toxicosis in chickens
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Al-Zubaidy MH, Mohammad F
- KMID: 1090799
- J Vet Sci.
- 2007 Sep;8(3):249-254.
- doi: 10.4142/jvs.2007.8.3.249
The efficacy of metoclopramide for preventing organo-phosphate insecticide-induced (diazinon) toxicosis wasevaluated in 7~14 days old chicks. Injection of metoclo-pramide at 25mg/kg, s.c. 15min before diazinon increasedthe oral 24 h median... -
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- Cerebral vasoreactivity by transcranial Doppler in carbon disulfide poisoning cases in Korea
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Lee E, Kim MH
- KMID: 1038446
- J Korean Med Sci.
- 1998 Dec;13(6):645-651.
- doi: 10.3346/jkms.1998.13.6.645
The abnormalities of cerebral vasoreactivity were evaluated in CS2 poisoning cases. In 34 retired workers with CS2 poisoning (case group) and 20 healthy individuals (control group), blood flow velocities... -
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- Cognitive Dysfunction in Drug-induced Parkinsonism Caused by Prokinetics and Antiemetics
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Ahn HJ, Yoo WK, Park J, Ma HI, Kim YJ
- KMID: 2344160
- J Korean Med Sci.
- 2015 Sep;30(9):1328-1333.
- doi: 10.3346/jkms.2015.30.9.1328
The use of prokinetics/antiemetics is one of the leading causes of drug-induced parkinsonism (DIP) observed in neurology clinics. Cognitive dysfunction in DIP has recently been recognized, but pathologies related with... -
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- DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells
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Zhou D, Wan Y, Xie D, Wang Y, Wei J, Yan Q, Lu P, Mo L, Xie J, Yang S, Qi X
- KMID: 2155436
- Exp Mol Med.
- 2015 Sep;47(9):e182.
- doi: 10.1038/emm.2015.57
Although methyltransferase has been recognized as a major element that governs the epigenetic regulation of the genome during temozolomide (TMZ) chemotherapy in glioblastoma multiforme (GBM) patients, its regulatory effect on... -
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- Lack of integrative control of body temperature after capsaicin administration
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Lee TH, Lee JW, Osaka T, Kobayashi , Namba Y, Inoue S, Kimura S
- KMID: 759501
- Korean J Intern Med.
- 2000 Jul;15(2):103-108.
BACKGROUND: Body temperature is usually regulated by opposing controls of heat production and heat loss. However, systemic administration of capsaicin, the pungent... -
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- Neurotoxic Manifestations of an Overdose Intrathecal Injection of Gadopentetate Dimeglumine
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Park KW, Im SB, Kim BT, Hwang SC, Park JS, Shin WH
- KMID: 1778054
- J Korean Med Sci.
- 2010 Mar;25(3):505-508.
- doi: 10.3346/jkms.2010.25.3.505
The intravenous administration of gadopentetate dimeglumine (GD) is relatively safe and rarely causes systemic toxicity in the course of routine imaging studies. However, the general safety of intrathecal GD has... -
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