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Angiogenesis and Mineralization During Distraction Osteogenesis

Choi IH, Chung CY, Cho TJ, Yoo WJ

Distraction osteogenesis is currently a standard method of bone lengthening. It is a viable method for the treatment of short extremities as well as extensive bone defects, because large amounts...
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The Immunohistochemical Patterns of Calcification-related Molecules in the Epidermis and Dermis of the Zebrafish (Danio rerio)

Hong YJ, Choi YW, Myung KB, Choi HY

BACKGROUND: The scales of bony fish represent a significant reservoir of calcium and calcification of the elasmoid scale is known to be associated with deposition of mineral crystals from the...
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Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway

Moon BS, Yoon JY, Kim MY, Lee SH, Choi T, Choi KY

Bone morphogenic protein 4 (BMP4), a member of the TGF-beta superfamily, induced neural differentiation of neural stem cells (NSCs) grown in a medium containing basic fibroblast growth factor (bFGF). The...
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Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro

Kim GH, Lee GR, Choi HI, Park NH, Chung HT, Han IS

  • KMID: 1397450
  • Exp Mol Med.
  • 2012 Jul;44(7):457-463.
Embryonic stem cells (ESCs) can be propagated in vitro on feeder layers of mouse STO fibroblast cells. The STO cells secrete several cytokines that are essential for ESCs to maintain...
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The Role of Microtubule in the Regulation of Endochondral Bone Formation in the Developing Mouse Cranial Base

Kwon HJ, Lee JM, Cho KW, Shin JO, Cho SW, Lee MJ, Jung HS

  • KMID: 1449629
  • Korean J Phys Anthropol.
  • 2011 Jun;24(2):105-112.
Endochondral bone formation of the developing cranial base is a complex process. This mechanism requires precise orchestration of many cellular events and cartilage matrix metabolism, such as proliferation, becoming round...
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Derivation of endothelial cells from porcine induced pluripotent stem cells by optimized single layer culture system

Wei R, Lv J, Li X, Li Y, Xu Q, Jin J, Zhang Y, Liu Z

Regenerative therapy holds great promise in the development of cures of some untreatable diseases such as cardiovascular diseases, and pluripotent stem cells (PSCs) including induced PSCs (iPSCs) are the most...
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In vitro differentiation of spermatogonial stem cells using testicular cells from Guangxi Bama mini-pig

Zhao H, Nie J, Zhu X, Lu Y, Liang X, Xu H, Yang X, Zhang Y, Lu K, Lu S

In this study, we attempted to establish a culture system for in vitro spermatogenesis from spermatogonial stem cells (SSCs) of Bama mini-pig. Dissociated testicular cells from 1-month-old pigs were co-cultured...
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Microarray Analysis of Short Heterodimer Partner (SHP)-induced Changes in Gene Expression in INS-1 Cells

Jung ED, Lee JH, Jang WG, Kim JG, Kim BW, Lee IK

BACKGROUND: Nuclear receptors are involved in the cell growth, development, differentiation, and metabolism. The orphan nuclear receptor SHP which lacks a DNA-binding domain is a negative regulator of nuclear receptor...
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