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Spontaneous Non-Traumatic Stress Fractures in Bilateral Femoral Shafts in a Patient Treated with Bisphosphonates

Shin DY, Ku CR, Kim KM, Choi HS, Rhee Y, Lee EJ, Lim SK

Bisphosphonates are potent inhibitors of bone resorption and widely used to treat osteoporosis. Extensive studies have shown that therapy with bisphosphonates improves bone density and decreases fracture risk. However, concerns...
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Combined Treatment with Vitamin K2 and Bisphosphonate in Postmenopausal Women with Osteoporosis

Iwamoto J, Takeda T, Ichimura S

  • KMID: 2428340
  • Yonsei Med J.
  • 2003 Oct;44(5):751-756.
Vitamin K2, as well as bisphosphonates, such as etidronate, alendronate, and risedronate, is widely used in the treatment with osteoporosis in Japan. Etidronate increases the lumbar bone mineral density (BMD),...
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Comparative Effects of Ibandronate and Paclitaxel on Immunocompetent Bone Metastasis Model

Chung YS, Kang HC, Lee T

PURPOSE: Bone metastasis invariably increases morbidity and mortality. This study compares the effects of ibandronate and paclitaxel on bone structure and its mechanical properties and biochemical turnover in resorption markers...
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Studies on the Effects of Biomedicinal Agents on Serum Concentration of Ca2+, P and ALP Activity in Osteoporosis-Induced Rats

Kim SK, Lee MH, Rhee MH

  • KMID: 1089405
  • J Vet Sci.
  • 2003 Aug;4(2):151-154.
The present study was carried out to investigate the effects of biomedicinal agents on Ca2+, P and alkaline phosphatase (ALP) levels in ovariectomized rats. Rats were ovariectomized bilaterally and were...
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Efficacy and Safety of Monthly 150 mg Oral Ibandronate in Women with Postmenopausal Osteoporosis: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Lee YH, Song GG

BACKGROUND/AIMS: The aim of this study was to assess the efficacy and safety of monthly oral 150 mg ibandronate in women with postmenopausal osteoporosis (PMO). METHODS: A systematic review and meta-analysis...
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At Least One Cyclic Teriparatide Administration Can Be Helpful to Delay Initial Onset of a New Osteoporotic Vertebral Compression Fracture

Suk KS, Lee HM, Moon SH, Kim HJ, Kim HS, Park JO, Lee BH

PURPOSE: Teriparatide markedly increases bone formation and strength, while reducing the incidence of new-onset osteoporotic vertebral compression fractures (OVCFs). In some countries, expenses for teriparatide use are covered by medical...
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Comparison of the Effect of Vitamin K2 and Risedronate on Trabecular Bone in Glucocorticoid-Treated Rats: A Bone Histomorphometry Study

Iwamoto J, Matsumoto , Tadeda T, Sato Y, Yeh JK

  • KMID: 2396058
  • Yonsei Med J.
  • 2009 Apr;50(2):189-194.
PURPOSE: To compare the effect of vitamin K2 and risedronate on trabecular bone in glucocorticoid (GC)-treated rats. MATERIALS AND METHODS: Forty-eight Sprague-Dawley female rats, 3 months of age, were randomized...
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Growth hormone replacement therapy in adults with growth hormone deficiency; thrice weekly low dose administration

Chung YS, Lee HC, Hwang SK, Paik IK, Lee JH, Huh KB

Recent reports on growth hormone (GH) therapy have shown that GH has various beneficial effects in GH deficient adults. In most of these studies, GH was administered daily. Because GH...
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A Comparison of Estrogen and Two Different Doses of Calcitonin in Ovariectomized Rats

Kavuncu V, Sahin S, Baydas G, Ilhan N, Ozercan I, Yasar A, Pekkutucu , Ilhan N, Ozercan R

The purpose of this study was to investigate the treatment efficacies of salmon calcitonin (SC) and estrogen in a type-I osteoporotic rat model. Sixty, 3-month-old, female Wistar rats were divided...
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