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Up-regulation of BLT2 is critical for the survival of bladder cancer cells

Seo JM, Cho KJ, Kim EY, Choi MH, Chung BC, Kim JH

The incidence rates of urinary bladder cancer continue to rise yearly, and thus new therapeutic approaches and early diagnostic markers for bladder cancer are urgently needed. Thus, identifying the key...
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Deletions of 9p21 and TP53 in bladder cancer

Park WS, Oh MJ, Lee HK, Lee KO, Rhyu MG, Dong SM, Lee JY, Kim SH

The objective of this study was to characterize the alterations of 9p21 and TP53 in Korean transitional bladder cancer and to assess the relationship between the histopathologic parameter and the...
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Analysis of p53 tumor suppressor gene mutations and human papillomavirus infection in human bladder cancers

Kim KH, Kim YS

To determine whether the dysfunction of p53 caused either by mutation of the p53 gene itself or by binding to E6 protein of oncogenic HPVs is involved in the transitional...
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Expression of survivin in squamous cell carcinoma and transitional cell carcinoma of the urinary bladder: A comparative immunohistochemical study

Makboul R, Refaiy AE, Badary FA, Abdelkawi , Merseburger AS, Mohammed R

PURPOSE: To compare the expression of survivin and its association with clinicopathological criteria in major types of urinary bladder carcinoma, specifically, transitional cell carcinoma with and without squamous differentiation and...
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Altered Gene Expression Profile After Exposure to Transforming Growth Factor beta1 in the 253J Human Bladder Cancer Cell Line

Lee C, Lee SH, Kim DS, Jeon YS, Lee NK, Lee SE

PURPOSE: Transforming growth factor beta1 (TGF-beta1) inhibits the growth of bladder cancer cells and this effect is prominent and constant in 253J bladder cancer cells. We performed a microarray analysis...
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Impaired Delta NP63 Expression is Associated with Poor Tumor Development in Transitional Cell Carcinoma of the Bladder

He Y, Wu X, Tang W, Tian D, Luo C, Yin Z, Du H

The oncogenic isoform of the p63 protein, delta NP63, plays an important role in the pathogenesis of many epithelial carcinomas, and emerging evidences suggest that delta NP63 is a promising...
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