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Dendroaspis natriuretic peptide regulates the cardiac L-type Ca2+ channel activity by the phosphorylation of alpha1c proteins

Park SA, Kim TG, Han MK, Ha KC, Kim SZ, Kwak YG

  • KMID: 1383798
  • Exp Mol Med.
  • 2012 Jun;44(6):363-368.
Dendroaspis natriuretic peptide (DNP), a new member of the natriuretic peptide family, is structurally similar to atrial, brain, and C-type natriuretic peptides. However, the effects of DNP on the cardiac...
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Suppression of CFTR-mediated Cl- Secretion of Airway Epithelium in Vitamin C-deficient Mice

Kim Y, Kim H, Yoo HY, Kang JS, Kim SJ, Kim JK, Cho HS

Hyperoxic ventilation induces detrimental effects on the respiratory system, and ambient oxygen may be harmful unless compensated by physiological anti-oxidants, such as vitamin C. Here we investigate the changes in...
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Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase

Park CE, Kim MJ, Lee JH, Min BI, Bae H, Choe W, Kim SS, Ha J

  • KMID: 1094663
  • Exp Mol Med.
  • 2007 Apr;39(2):222-229.
trans-Resveratrol (t-RVT), a naturally occurring polyphenol found in Polygonum cuspidatum, grape, and red wine, has been reported to have anti- inflammatory, cardioprotective, and cancer chemopreventive properties. However antidiabetic effect of...
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A point mutant of apolipoprotein A-I, V156K, exhibited potent anti-oxidant and anti-atherosclerotic activity in hypercholesterolemic C57BL/6 mice

Cho KH, Park SH, Han JM, Kim HC, Chung YJ, Choi I, Kim JR

  • KMID: 1094656
  • Exp Mol Med.
  • 2007 Apr;39(2):160-169.
In our previous study, two point mutants of apolipoprotein A-I, designated V156K and A158E, revealed peculiar characteristics in their lipid-free and lipid-bound states. In order to determine the putative therapeutic...
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Effects of glutamate on dehydroascorbate uptake and Its enhanced vulnerability to the peroxidation in cerebral cortical slices

Song JH, Shin SH, Chung IM

  • KMID: 1121095
  • Exp Mol Med.
  • 2002 Dec;34(6):419-425.
Pro-oxidant properties of ascorbate have been studied with uses of brain tissues and neuronal cells. Here we address potential mechanism of ascorbate coupling with glutamate to generate oxidative stress,...
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Dexamethasone enhances phospholipase D activity in M-1 cells

Kim WJ, Lee MJ, Park MA, Jung JS, Uhlinger D, Kwak JY

  • KMID: 755082
  • Exp Mol Med.
  • 2000 Sep;32(3):170-177.
Phospholipase D (PLD) is an enzyme involved in signal transduction and widely distributed in mammalian cells. The signal transduction pathways and role for phospholipid metabolism during hormonal response in...
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Calcium-dependent and -independent mechanisms of P2Y receptor regulated anion secretion in polarized epithelia

Wong HY, Ko WH

No abstract available.
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Unexpected effects of pathogens on epithelial Na+ channels

Kunzelmann K, Beesley A, King N, Karupiah G, Young J, Cook D

No abstract available.
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Beta agonist regulation of sodium transport in fetal lung epithelium: roles of cell volume, cytosolic chloride and protein tyrosine kinase

Marunaka Y, Niisato N, Ito Y

1) A beta agonist stimulated Na+ transport and decreased the intracellular Cl concentration ([Cl]c) associated with cell shrinkage via an increase in cytosolic cAMP level by activating adenylate cyclase in...
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A novel Na+-dependent transporter and NHE3 mediate H+ efflux in the luminal membrane of the pancreatic duct: regulation by cAMP

Lee MG, Ahn W, Choi JY, Muallem S, Kim KH

No abstract available.
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