- The inhibition of inflammatory molecule expression on 3T3-L1 adipocytes by berberine is not mediated by leptin signaling
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Choi BH, Kim YH, Ahn IS, Ha JH, Byun JM, Do MS
- KMID: 2313381
- Nutr Res Pract.
- 2009 Jun;3(2):84-88.
In our previous study, we have shown that berberine has both anti-adipogenic and anti-inflammatory effects on 3T3-L1 adipocytes, and the anti-adipogenic effect is due to the down-regulation of adipogenic enzymes... -
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- Antifungal Activity of Chaerophylline and Berberine Hydroxide Isolated from Corydalis Species
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Tuli L, Jha RN, Pandey VB, Singh UP
- KMID: 1993710
- Mycobiology.
- 2001 Jun;29(2):100-103.
Chaerophylline and berberine hydroxide, both being alkaloids, isolated from Corydalis chaerophylla and C. longipes respectively were assayed against spore germination of some fungi, e.g. Alternaria solani, A. brassicola, A. brassicicola,... -
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- Antibacterial Effects Of Berberine On Antibiotic-Resistant Staphylococcus Aureus
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Kim KJ, Cha JD, Kim HK, You HH, You YO, Lee DK
- KMID: 1960645
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2002 Mar;24(2):108-114.
Antibiotic-resistant Staphylococcus aureus (S. aureus )emerged in many parts of the world and increased complex clinical problems.Therefore,new agents are needed to treat the antibiotic-resistant S. aureus .Some natural products are... -
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- Antimicrobial Activity of Berberine against Oral Bacteria Related to Endodontic Infections
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Lee D, Kim MJ, Park SN, Lim YK, Min JB, Hwang HK, Kook JK
- KMID: 1709607
- Int J Oral Biol.
- 2013 Dec;38(4):141-147.
It has been established that berberine has strong antimicrobial effects. Little is known however regarding the antimicrobial activity of berberine against endodontic pathogenic bacteria or its cytotoxicity in human oral... -
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- Effect of Berberine on Cell Survival in the Developing Rat Brain Damaged by MK-801
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Lee T, Heo H, Kim Y
- KMID: 1460758
- Exp Neurobiol.
- 2010 Dec;19(3):140-145.
- doi: 10.5607/en.2010.19.3.140
Berberine is an isoquinoline alkaloid isolated from goldenthread, Coptidis Rhizoma and shown to have many biological and pharmacological effects. We previously reported that berberine promotes cell survival and differentiation of... -
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- Berberine Inhibited the Growth of Thyroid Cancer Cell Lines 8505C and TPC1
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Park KS, Kim JB, Bae J, Park SY, Jee HG, Lee KE, Youn YK
- KMID: 1120201
- Yonsei Med J.
- 2012 Mar;53(2):346-351.
- doi: 10.3349/ymj.2012.53.2.346
PURPOSE: Thyroid cancer is the most common malignancy in Korean females and can be treated with good prognosis. However, drugs to treat aggressive types of thyroid cancer such as poorly... -
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- Activating transcription factor-3 induction is involved in the anti-inflammatory action of berberine in RAW264.7 murine macrophages
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Bae YA, Cheon HG
- KMID: 2371059
- Korean J Physiol Pharmacol.
- 2016 Jul;20(4):415-424.
- doi: 10.4196/kjpp.2016.20.4.415
Berberine is an isoquinoline alkaloid found in Rhizoma coptidis, and elicits anti-inflammatory effects through diverse mechanisms. Based on previous reports that activating transcription factor-3 (ATF-3) acts as a negative regulator... -
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- Berberine Suppresses Interleukin-1beta-Induced MUC5AC Gene Expression in Human Airway Epithelial Cells
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Kim KR, Kim NH, Park Y, Kim JH, Lee EJ, Kim KS
- KMID: 2297593
- J Rhinol.
- 2011 Nov;18(2):116-121.
OBJECTIVES: The aim of this study was to investigate whether berberine suppresses interleukin (IL)-1beta-induced MUC5AC gene expression in human airway epithelial cells and, if so, to determine which mitogen-activated protein... -
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- Enhancement of Arsenic Trioxide (As2O3)-Mediated Apoptosis Using Berberine in Human Neuroblastoma SH-SY5Y Cells
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Kim DW, Ahan SH, Kim TY
- KMID: 1956216
- J Korean Neurosurg Soc.
- 2007 Nov;42(5):392-399.
- doi: 10.3340/jkns.2007.42.5.392
OBJECTIVE: Arsenic trioxide (As2O3) has been used as an anticancer agent in traditional Chinese medicine for thousand years and berberine is an isoquinoline alkaloid present that has indicated significant antimicrobial... -
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- Combination of berberine and ciprofloxacin reduces multi-resistant Salmonella strain biofilm formation by depressing mRNA expressions of luxS, rpoE, and ompR
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Shi C, Li M, Muhammad I, Ma X, Chang Y, Li R, Li C, He J, Liu F
- KMID: 2427029
- J Vet Sci.
- 2018 Nov;19(6):808-816.
- doi: 10.4142/jvs.2018.19.6.808
Bacterial biofilms have been demonstrated to be closely related to clinical infections and contribute to drug resistance. Berberine, which is the main component of Coptis chinensis, has been reported to... -
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- Inhibitory Effects of Isoquinoline Alkaloid Berberine on Ischemia-Induced Apoptosis via Activation of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Pathway
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Kim M, Shin MS, Lee JM, Cho HS, Kim CJ, Kim YJ, Choi HR, Jeon JW
- KMID: 2232938
- Int Neurourol J.
- 2014 Sep;18(3):115-125.
- doi: 10.5213/inj.2014.18.3.115
PURPOSE: Berberine is a type of isoquinoline alkaloid that has been used to treat various diseases. A neuroprotective effect of berberine against cerebral ischemia has been reported; however, the effects... -
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- Berberine Prevents Intestinal Mucosal Barrier Damage During Early Phase of Sepsis in Rat through the Toll-Like Receptors Signaling Pathway
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Li GX, Wang XM, Jiang T, Gong JF, Niu LY, Li N
- KMID: 2071812
- Korean J Physiol Pharmacol.
- 2015 Jan;19(1):1-7.
- doi: 10.4196/kjpp.2015.19.1.1
Our previous study has shown berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway. In... -
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- Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats
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Kim M, Kim TW, Kim CJ, Shin MS, Hong M, Park HS, Park SS
- KMID: 2467318
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S102-S110.
- doi: 10.5213/inj.1938216.108
PURPOSE: Hyperlipidemia, which promotes the development of atherosclerosis, ischemic stroke, and other forms of brain injury, can be induced by poloxamer-407. Berberine is a primary pharmacological active component of Coptidis... -
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- Effect Of Several Extracts Of The Plants On Nosocomial Pathogens
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Moon SE, Kwon KH, Kim KJ
- KMID: 1960616
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2002 Nov;24(6):499-507.
To investigate the cross contamination in the dental clinic,Staphylococcus aureus, the pathogen in acute pyogenic infection and one of the important microbes causing nosocomial infection,was isolated from the mouth and... -
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- Pharmacological Effects of Berberine and Palmatine on the Prostatic and Urethral Smooth Muscle of the Rabbit
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Oh SJ, Kang J, Jeong JY, Lee KH, Kim SJ, Chung YS, Hong EK, Kim KM
- KMID: 2330478
- J Korean Continence Soc.
- 2002 Dec;6(2):62-71.
PURPOSE: One of the major medical treatments for benign prostatic hyperplasia is targeted toward reducing bladder outlet obstruction by alpha-adrenoceptor blockade to relax the smooth muscle tone of the prostate.... -
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- Effect of Berberine on Depression- and Anxiety-Like Behaviors and Activation of the Noradrenergic System Induced by Development of Morphine Dependence in Rats
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Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2285445
- Korean J Physiol Pharmacol.
- 2012 Dec;16(6):379-386.
- doi: 10.4196/kjpp.2012.16.6.379
The purpose of this study was to evaluate whether berberine (BER) administration could attenuate depression- and anxiety-like behaviors and increase corticotrophin-releasing factor (CRF) and tyrosine hydroxylase (TH) expression following chronic... -
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- Berberine Suppresses Fibronectin Expression through Inhibition of c-Jun Phosphorylation in Breast Cancer Cells
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Jeong Y, You D, Kang HG, Yu J, Kim SW, Nam SJ, Lee JE, Kim S
- KMID: 2441864
- J Breast Cancer.
- 2018 Mar;21(1):21-27.
- doi: 10.4048/jbc.2018.21.1.21
PURPOSE: The exact mechanism regulating fibronectin (FN) expression in breast cancer cells has not been fully elucidated. In this study, we investigated the pharmacological mechanism of berberine (BBR) with respect... -
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- Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte
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Choi BH, Ahn IS, Kim YH, Park JW, Lee SY, Hyun CK, Do MS
- KMID: 1115937
- Exp Mol Med.
- 2006 Dec;38(6):599-605.
Berberine (BBR), an isoquinoline alkaloid, has a wide range of pharmacological effects, yet its exact mechanism is unknown. In order to understand the anti-adipogenic effect of BBR, we studied the... -
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- Virtual Screening for Potential Inhibitors of NS3 Protein of Zika Virus
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Sahoo M, Jena L, Daf S, Kumar S
- KMID: 2353662
- Genomics Inform.
- 2016 Sep;14(3):104-111.
- doi: 10.5808/GI.2016.14.3.104
Zika virus (ZIKV) is a mosquito borne pathogen, belongs to Flaviviridae family having a positive-sense single-stranded RNA genome, currently known for causing large epidemics in Brazil. Its infection can cause... -
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- Trends in the incidence of ulcerative colitis in Korea
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Yang DH, Yang SK
- KMID: 2257255
- Korean J Med.
- 2009 Jun;76(6):637-642.
Ulcerative colitis is an idiopathic chronic inflammatory disease of the colon that has traditionally been considered rare in Korea. The incidence of ulcerative colitis, however, has increased recently. According to... -
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