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Editor's Introduction to This Issue (G&I 15:2, 2017)

Chung YJ

No abstract available.
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Virulence factors of Helicobacter pylori and their clinical significances

Lee YC

  • KMID: 1523321
  • Hanyang Med Rev.
  • 2007 Aug;27(3):28-33.
Helicobacter pylori (H. pylori) is known be an etiologic factor for gastric and duodenal ulcer, gastric noncardiac adenocarcinoma, and MALT lymphoma in a subset of infected individuals. Pathogenesis of H....
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Effects of Some Drugs and Toxins on Positive Rate of Y-Body in Leukocytes of Rabbits

Yun NS, Lee HY

  • KMID: 2060007
  • Korean J Urol.
  • 1976 Jun;17(2):77-94.
This study was carried out to investigate the response of interphase Y chromosome to some drugs and toxins by observing the rate of leukocytes showing Y-body in the peripheral blood....
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Acute Postoperative Unilateral Pulmonary Edema

Lee HW, Lim HJ, Chang SH, Shin JS

There are many predisposing factors for acute pulmonary edema, namely, left ventricular failure due to cardiac disease or fluid overloading, hypoalbuminemia, pulmonary capillary endothelial damage from bacterial toxins or irritant...
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Evaluation of Rapid Assay (Tox A/B Quik Chek) for the Detection of Clostridium difficile Toxins A and B

Kim SJ, Kim H, Kim MS, Koh E, Kim CK, Jeong SH, Chong Y, Lee K

BACKGROUND: Toxin immunoassay is widely used for rapid diagnosis of Clostridium difficile-associated diarrhea. The aim of this study was to evaluate the performance of Tox A/B Quik Chek test (TECHLAB,...
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Helicobacter pylori Infection

Song JH, Kim JJ

Helicobacter pylori (H. pylori) causes chronic gastritis, peptic ulcer disease, primary B-cell gastric lymphoma, and adenocarcinoma of the stomach. The overall seroprevalence of H. pylori infection in Korea was 46.6%,...
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Nuclear Factor-kappa B Activation and Chemokine Genes Expression in HT-29 Intestinal Epithelial Cells in Response to Clostridium difficile Toxin A Stimulation

Lee JY, Yoon YM, Roh HC, Kim JM

  • KMID: 1574164
  • J Bacteriol Virol.
  • 2005 Sep;35(3):217-226.
Intestinal epithelial cells are known to up-regulate the expression of several chemokines in response to bacterial toxins. Since there has been little understanding on the cellular mechanisms of C. difficile...
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Production of IL - 6 and IL - 8 in Human Fibroblasts Stimulated with Mycoplasma Lysates and Bacterial Toxins

Kim KH, Chang MW

  • KMID: 2099317
  • J Korean Soc Microbiol.
  • 1999 Dec;34(6):573-582.
Cytokines are hormone-like proteins which mediate and regulate inflammatory and immune responses. The purpose of this study was to investigate the effect of lipopolysaccharide (LPS), Staphylococcus enterotoxin B (SEB), and...
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A Fatal Case of Infective Endocarditis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus ST72 in Korea

Choi SH, Chung JW

The advent of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a worldwide threat to public health for the past decade. We report a fatal case of infective endocarditis caused by...
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Development of two novel nontoxic mutants of Escherichia coli heat-labile enterotoxin

Park EJ, Chang JH, Kim JS, Chung SI, Yum JS

  • KMID: 1029939
  • Exp Mol Med.
  • 1999 Jun;31(2):101-107.
Escherichia coli heat-labile enterotoxin (LT) is composed of catalytic A and non-catalytic homo-pentameric B subunits and causes diarrheal disease in human and animals. In order to produce a nontoxic LT for vaccine...
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Equine hyperimmune serum protects mice against Clostridium difficile spore challenge

Yan W, Shin KS, Wang SJ, Xiang H, Divers T, McDonough , Bowman J, Rowlands A, Akey B, Mohamed H, Chang YF

Clostridium (C.) difficile is a common cause of nosocomial diarrhea in horses. Vancomycin and metronidazole have been used as standard treatments but are only moderately effective, which highlights the need...
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Comparison of ChromID Agar and Clostridium difficile Selective Agar for Effective Isolation of C. difficile from Stool Specimens

Shin BM, Lee EJ

BACKGROUND: ChromID Clostridium difficile agar (IDCd; bioMerieux SA, France) is a recently developed chromogenic medium for rapid and specific isolation of C. difficile. We compared the performance of IDCd with...
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Cholesterol induce oligomerization of Vibrio vulnificus cytolysin specifically.

Kim BS, Kim JS

  • KMID: 1380232
  • Exp Mol Med.
  • 2002 Jul;34(3):239-242.
Vibrio vulnificus cytolysin (VVC) has been implicated as one of the important virulence determinants of V. vulnificus that causes serious septicemia and wound infection. An attempt was made to investigate...
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Peptidoglycan Induces the Production of Interleukin-8 via Calcium Signaling in Human Gingival Epithelium

Son A, Shin DM, Hong JH

The etiology of periodontal disease is multifactorial. Exogenous stimuli such as bacterial pathogens can interact with toll-like receptors to activate intracellular calcium signaling in gingival epithelium and other tissues. The...
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Production of Transforming Growth Factor-beta1 in Human Fibroblasts Induced with Bacterial Toxins

Lee SG, Kim KH

  • KMID: 2005997
  • J Korean Assoc Oral Maxillofac Surg.
  • 2000 Aug;26(4):345-354.
TGF-beta1 is a potent chemotactic factor for inflammatory cells and fibroblasts. It also stimulates the celluar source and components of extracellular matrix and the production of proteinase inhibitors. Collectively, these...
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The Role of Inflammatory Mediators in the Pathogenesis of Otitis Media and Sequelae

Juhn SK, Jung MK, Hoffman MD, Drew BR, Preciado D, Sausen NJ, Jung TT, Kim BH, Park SY, Lin J, Ondrey FG, Mains DR, Huang T

This review deals with the characteristics of various inflammatory mediators identified in the middle ear during otitis media and in cholesteatoma. The role of each inflammatory mediator in the pathogenesis...
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House Dust Mite Extract Induces PLC/IP3-dependent Ca2+ Signaling and IL-8 Expression in Human Gingival Epithelial Cells

Son GY, Son A, Park W, Shin DM

The gingival epithelium of the oral cavity is constantly exposed to exogenous stimuli such as bacterial toxins, allergens, and thermal changes. These exogenous stimuli are resisted by innate host defense...
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Evaluation of a Rapid Membrane Enzyme Immunoassay for the Simultaneous Detection of Glutamate Dehydrogenase and Toxin for the Diagnosis of Clostridium difficile Infection

Kim H, Kim WH, Kim M, Jeong SH, Lee K

We evaluated the new C. DIFF QUIK CHEK COMPLETE (CD COMPLETE; TechLab, USA), which is a rapid membrane enzyme immunoassay that uses a combination of glutamate dehydrogenase (GDH) antigen and...
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The mucosal adjuvanticity of two nontoxic mutants of Escherichia coli heat-labile enterotoxin varies with immunization routes

Park EJ, Chang JH, Kim JS, Yum JS, Chung SI

  • KMID: 1109305
  • Exp Mol Med.
  • 2000 Jun;32(2):72-78.
Escherichia coli heat-labile enterotoxin (LT), which causes a characteristic diarrhea in humans and animals, is a strong mucosal immunogen and has powerful mucosal adjuvant activity towards coadministered unrelated antigens. Here...
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Correlation Between Virulence Genotype and Fluoroquinolone Resistance in Carbapenem-Resistant Pseudomonas aeruginosa

Cho HH, Kwon KC, Kim S, Koo SH

BACKGROUND: Pseudomonas aeruginosa is a clinically important pathogen that causes opportunistic infections and nosocomial outbreaks. Recently, the type III secretion system (TTSS) has been shown to play an important role...
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