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Antigen-binding Characteristics of Circulating IgG Autoantibodies to Cytokeratin 18 Protein in Patients with Nonallergic Asthma

Yim H, Kim JE, Shin JY, Ye YM, Park HS, Nahm DH

Cytokeratin 18 (CK18) protein was identified as an airway epithelial cell autoantigen associated with nonallergic asthma. Cleavage of CK18 protein by caspase-3 is a marker of early apoptosis in epithelial...
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Presence of circulating autoantibodies against bronchial epithelia cell in patients with nonatopic asthma

Nahm DH, Yim H, Lee HJ, Yim EJ, Choi EA, Kim SS, Lee SK, Park HS

Allergic response to common environmental agents has been regarded as a main pathogenetic mechanism of bronchial asthma. However, allergic sensitization (atopy) can not be detected in a siginificant number of...
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Development of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy

Jang SY, Lee KH, Oh JR, Kim BY, Yoon JS

PURPOSE: To report clinical characteristics of thyroid-associated ophthalmopathy (TAO) in patients who previously underwent total thyroidectomy for thyroid cancer or a benign mass of the thyroid. MATERIALS AND METHODS: Of the...
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Transient Acquired Hemophilia Associated with Mycoplasma Pneumoniae Pneumonia

Kim MS, Kilgore PE, Kang JS, Kim SY, Lee DY, Kim JS, Hwang PH

Acquired hemophilia is a rare disorder caused by autoantibodies to factor VIII (FVIII) (also referred to as factor VIII inhibitors or anti-FVIII) and may be associated with pregnancy, underlying malignancy,...
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Prospective Observation of 5-Year Clinical Course of Subclinical Hypothyroidism in Korean Population

Park WR, Oh TK, Jeon HJ

Subclinical hypothyroidism (SCH) is a common clinical condition, whereas it's natural course has not been identified distinctly. We evaluated the natural history of 169 SCH patients over 5-yr and the...
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Increased Level of Basophil CD203c Expression Predicts Severe Chronic Urticaria

Ye YM, Yang EM, Yoo HS, Shin YS, Kim SH, Park HS

Increased FcepsilonR1alpha expression with upregulated CD203c expression on peripheral basophils is seen in patients with chronic urticaria (CU). However, there has been no published report on the association between CD203c...
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The First Case of Postpartum Acquired Hemophilia A in Korea

Lee JH, Kim DH, Yoo K, Choi Y, Kim SH, Kim HJ

Acquired hemophilia A (AHA) is a rare coagulopathy caused by autoantibodies to coagulation factor VIII (FVIII). Most patients with AHA have been previously healthy; however, a variety of morbidities have...
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Incidence of and risk factors for thyroid dysfunction during peginterferon alpha and ribavirin treatment in patients with chronic hepatitis C

Hwang Y, Kim W, Kwon SY, Yu HM, Kim JH, Choe WH

BACKGROUND/AIMS: Thyroid dysfunction (TD) is more likely to occur in patients with chronic hepatitis C (CHC) and is particularly associated with interferon (IFN) treatment. The purpose of this study was...
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Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis: Is There Additional Value of Bone Scintigraphy with Blood Pool Phase over Conventional Bone Scintigraphy?

Kim JY, Choi YY, Kim CW, Sung YK, Yoo DH

We aimed to investigate the value of bone scintigraphy with additional blood pool phase (BSBP), compared with conventional bone scintigraphy (CBS), in the assessment of rheumatoid arthritis (RA). A total...
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Preoperative Serum Thyroglobulin as a Useful Predictive Marker to Differentiate Follicular Thyroid Cancer from Benign Nodules in Indeterminate Nodules

Lee EK, Chung KW, Min HS, Kim TS, Kim TH, Ryu JS, Jung YS, Kim SK, Lee YJ

Indeterminate cytology results increase the number of repetitive procedure and unnecessary surgery. This study was designed to find useful and simple predictive tools to differentiate malignant thyroid nodules from indeterminate...
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Increased Prevalence of Autoimmune Thyroid Disease in Patients with Type 1 Diabetes

Park YS, Kim TW, Kim WB, Cho BY

  • KMID: 759519
  • Korean J Intern Med.
  • 2000 Dec;15(3):202-210.
BACKGROUND: Type 1 diabetes mellitus is frequently associated with other autoimmune diseases. The occurrence of common features of autoimmune diseases and the coassociation of multiple autoimmune diseases in the same...
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Antibiotic-induced Severe Neutropenia with Multidrug-Dependent Antineutrophil Antibodies Developed in A Child with Streptococcus pneumoniae Infection

Lee YH, Lee HB, Kim JY, Lim YJ, Shin SA, Han TH

Drug-induced neutropenia (DIN), particularly that in which antibiotic-dependent antineutrophil antibodies have been detected, is a rare disorder. We report the case of a child with pneumococcal pneumonia, who experienced severe...
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Detection of antibodies to human melanoma cell in vitiligo by western blot analysis

Hann SK, Kim JB

Vitiligo is a disease in which melanocytes are selectively destroyed. The disease is thought to be an autoimmune process being there are antibodies to pigment cells in the sera of...
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The Significance of Ectopic Germinal Centers in the Minor Salivary Gland of Patients with Sjogren's Syndrome

Lee KE, Kang JH, Yim YR, Kim JE, Lee JW, Wen L, Park DJ, Kim TJ, Park YW, Yoon KC, Lee JS, Lee SS

We investigated the clinical and biological significance of germinal centers (GC) present in the minor salivary glands of patients with Sjogren's syndrome (SS). Minor salivary gland tissue biopsies from 93...
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The diagnosis and treatment of primary biliary cirrhosis

Kim KA, Jeong SH

Primary biliary cirrhosis (PBC) is a slowly progressive cholestatic liver disease of autoimmune etiology. The initial presentation of PBC is various from asymptomatic, abnormal liver biochemical tests to overt cirrhosis....
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Visceral Leishmaniasis Mimicking Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Systemic Lupus Erythematosus Overlap

Tunccan OG, Tufan A, Telli G, Akyurek N, Pamukcuoglu M, Yilmaz G, Hizel K

Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date,...
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The Effects of Intradermal Vaccination with DNA Encoding for the T-cell Receptor on the Induction of Experimental Autoimmune Encephalomyelitis in B10.PL Mice

Kwon SS, Kim N, Yoo TJ

Intradermal gene administration was found to induce a more profound immune response than direct intramusclular gene injection. We performed intradermal vaccination of B10.PL mice with DNA encoding for the V...
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