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Development of a UPLC-MS/MS method for the therapeutic monitoring of L-asparaginase

Jeong HC, Kim T, Yang DH, Shin KH

This study aimed to develop a UPLC-MS/MS method for determining plasma levels of L-aspartic acid and L-asparagine and the activity of L-asparaginase. L-aspartic acid, L-asparagine, and L-aspartic acid-2,3,3-d3 were extracted...
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Cultural Characteristics of Veiled Lady Mushroom, Dictyophora spp.

Cheong JC, Kim GP, Kim HK, Park JS, Chung BK

  • KMID: 2312326
  • Mycobiology.
  • 2000 Dec;28(4):165-170.
This study was carried out to obtain the basic data for artificial culture of veiled lady mushroom (Dictyophora spp). The optimal conditions for the mycelial growth were 25degrees C and...
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Development of a novel vaccine against canine parvovirus infection with a clinical isolate of the type 2b strain

Park SA, Park SY, Song CS, Choi IS, Kim HY, Lee JB, Lee NH

PURPOSE: In spite of an extensive vaccination program, parvoviral infections still pose a major threat to the health of dogs. MATERIALS AND METHODS: We isolated a novel canine parvovirus (CPV) strain...
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Three New Non-reducing Polyketide Synthase Genes from the Lichen-Forming Fungus Usnea longissima

Wang Y, Wang J, Cheong YH, Hur JS

  • KMID: 2312720
  • Mycobiology.
  • 2014 Mar;42(1):34-40.
Usnea longissima has a long history of use as a traditional medicine. Several bioactive compounds, primarily belonging to the polyketide family, have been isolated from U. longissima. However, the genes...
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Four Cases of Acute Parotitis in Acute Lymphoblastic Leukemia Patients Developed during Induction Chemotherapy Including L-Asparaginase

Lee JH, Lee JA, Han HJ, Choi Y, Choi HS, Shin HY, Ahn HS

  • KMID: 2072487
  • Korean J Pediatr Hematol Oncol.
  • 1999 Apr;6(1):146-150.
L-asparaginase is an essential chemotherapeutic agent in the treatment of the acute lymphoblastic leukemia or non-Hodgkin lymphoma with its unique mechanism of action. It has many toxic effects involving...
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Optimal Extraction Conditions of Anti-obesity Lipase Inhibitor from Phellinus linteus and Nutritional Characteristics of the Extracts

Lee JK, Song JH, Lee JS

  • KMID: 2312565
  • Mycobiology.
  • 2010 Mar;38(1):58-61.
In an effort to develop novel mushroom-derived anti-obesity nutraceuticals, water and ethanol extracts containing the lipaseinhibitory compound from Phellinus linteus were prepared, and their nutritional components were determined. The optimal...
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Expression of Human Papillomavirus Type 16, Prototype and Natural Variant E7 Proteins using Baculovirus Expression System

Han HS, Kee SH, Kim HJ, Cho KA, Kim YW, Cho MK, Chang WH, Hwang SB

  • KMID: 1940945
  • J Korean Soc Virol.
  • 1998 Mar;28(1):53-62.
Human papillomavirus (HPV) 16, E7 proteins derived from the prototype (Bac73) and natural variant (Bac101) E7 open reading frame were produced in Sf9 insect cells. The variant E7 gene occurred...
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Alterations of Amino Acid Level in Depressed Rat Brain

Yang P, Li X, Ni J, Tian J, Jing F, Qu C, Lin L, Zhang H

Amino-acid neurotransmitter system dysfunction plays a major role in the pathophysiology of depression. Several studies have demonstrated the potential of amino acids as a source of neuro-specific biomarkers could be...
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Correlation Between Gastric Emptying and Gastric Adaptive Relaxation Influenced by Amino Acids

Uchida M, Kobayashi , Saito C

  • KMID: 2387831
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):400-408.
  • doi: 10.5056/jnm16153
BACKGROUND/AIMS: Amino acids have many physiological activities. We report the correlation between gastric emptying and gastric adaptive relaxation using tryptophan and amino acids with a straight alkyl chain, hydroxylated chain,...
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Influence of Physiological and Environmental Factors on Growth and Sporulation of an Antagonistic Strain of Trichoderma viride RSR 7

Jayaswal R, Singh R, Lee YS

Influence of physiological and environmental factors on an antagonistic strain of Trichoderma viride RSR7 were studied optimize its biocontrol potential. The growth and sporulation of T. viride was greatly influenced...
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Cross-reactivity of Vaccine and Fields Strains of Bovine Coronaviruses in Korea

Lee G, Song JY, Cho IS, Yoon S

Bovine coronavirus (BCoV) causes severe diarrhea in newborn calves, and is associated with winter dysentery in adult cattle and respiratory infections in calves and feedlot cattle. Although the Korean BCoV...
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Host Gene Profiling of Coxsackievirus B3 H3- and 10A1-infected Mouse Heart

Nam JH, Lim BK, Cho YJ, Kim DS, Kim YJ, Chung SY, Jee YM, Jeon ES

Coxsackievirus B3 (CVB3) is a non-enveloped virus that has a single-stranded RNA genome. CVB3 induces myocarditis, and ultimately, dilated cardiomyopathy. A myocarditis variant of CVB3 (CVB3 H3) and its antibody-escape...
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Physical Modeling of Chemical Exchange Saturation Transfer Imaging

Jahng GH, Oh JH

Chemical Exchange Saturation Transfer (CEST) imaging is a method to detect solutes based on the chemical exchange of mobile protons with water. The solute protons exchange with three different patterns,...
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Age Specific Reference Values of 24 Plasma Free Amino Acids in Korean Children

Lee KO, Ryu KS, Seo DK, Lee KH

  • KMID: 2135524
  • J Clin Pathol Qual Control.
  • 1998 Jun;20(1):155-162.
BACKGROUND: For early and accurate detection of amino acid disorders, such as inborn error of metabolism, metabolic acidosis, liver disease and kidney disease, establishment of reference value of amino acids...
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Preliminary Phantom Experiments to Map Amino Acids and Neurotransmitters Using MRI

Oh JH, Kim HG, Woo DC, Rhee SJ, Lee SY, Jahng GH

The objective of this study was to evaluate the chemical exchange saturation transfer (CEST) effect of amino acids and neurotransmitters, which exist in the human brain, depending on the concentration,...
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Expression and Purification of Glycoprotein G1 of Hantaan Virus in E. coli System

Choi KR, Nam JH, Choi WY, Ju YR, Park KY, Cho HW

  • KMID: 2054964
  • J Bacteriol Virol.
  • 2002 Dec;32(4):421-430.
Envelope glycoprotein 1 (G1) and glycoprotein 2 (G2) of Hantaan (HTN) virus are believed to be major viral antigens that can induce neutralizing immunity against HTN virus infection. The purpose...
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A Case of Adult Fanconi Syndrome with Hypophosphatemic Osteomalacia

Lee JH, Byun YS, Cha BS, Nam MS, Song YD, Lim SK, Kim KR, Lee HC, Huh KB, Kim J, Yook JI

  • KMID: 2461609
  • J Korean Soc Endocrinol.
  • 1996 Mar;11(1):93-101.
The Fanconi syndrome is characterized by generalized disturbance of tubular function. It leads to excessive losses of amino acids, glucose, phosphate, bicarbonate, and other organic and inorganic substrates handled by...
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Enzymatic N-glycan analysis of 31 kDa molecule in plerocercoid of Spirometra mansoni (sparganum) and its antigenicity after chemical oxidation

Chung YB, Kong Y, Yang HJ

A highly specific antigenic protein of 31 kDa from plerocercoid of Spirometra mansoni (sparganum) was obtained by gelatin affinity and Mono Q anion-exchange column chromatography. The purified 31 kDa protein...
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