- Oral health-related quality of life in patients with implant treatment
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Kanehira Y, Arai K, Kanehira T, Nagahisa K, Baba S
- KMID: 2398053
- J Adv Prosthodont.
- 2017 Dec;9(6):476-481.
- doi: 10.4047/jap.2017.9.6.476
PURPOSE: Patient-reported outcomes are increasingly commonly used as a method of evaluating treatments. This cross-sectional study aimed to evaluate implant treatment from the perspective of patient-reported outcomes. MATERIALS AND METHODS: Subjects... -
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- Role of A-Kinase Anchoring Protein 12 in the Central Nervous System
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Kimura S, Lok J, Gelman IH, Lo EH, Arai K
- KMID: 2543827
- J Clin Neurol.
- 2023 Jul;19(4):329-337.
- doi: 10.3988/jcn.2023.0095
A-kinase anchoring protein (AKAP) 12 is a scaffolding protein that anchors various signaling proteins to the plasma membrane. These signaling proteins include protein kinase A, protein kinase C, protein phosphatase... -
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- Very Early-Onset Inflammatory Bowel Disease: A Challenging Field for Pediatric Gastroenterologists
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Arai K
- KMID: 2506134
- Pediatr Gastroenterol Hepatol Nutr.
- 2020 Sep;23(5):411-422.
- doi: 10.5223/pghn.2020.23.5.411
With the increasing number of children with inflammatory bowel disease (IBD), very earlyonset IBD (VEO-IBD), defined as IBD that is diagnosed or that develops before 6 years of age, has... -
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- Features and Outcomes of Children with Ulcerative Colitis who Undergo a Diagnostic Change: A Single-Center Experience
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Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K
- KMID: 2518435
- Pediatr Gastroenterol Hepatol Nutr.
- 2021 Jul;24(4):357-365.
- doi: 10.5223/pghn.2021.24.4.357
Purpose: A change in diagnosis from ulcerative colitis (UC) to Crohn's disease (CD) has been reported in pediatric inflammatory bowel disease; however, only a few clinical characteristics and predictors of... -
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- Long-Term Efficacy and Safety of Golimumab for Ulcerative Colitis in a Pediatric Inflammatory Bowel Disease Center in Japan
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Tokita K, Shimizu H, Takeuchi I, Shimizu T, Arai K
- KMID: 2535163
- Pediatr Gastroenterol Hepatol Nutr.
- 2022 Nov;25(6):461-472.
- doi: 10.5223/pghn.2022.25.6.461
Purpose: Golimumab (GLM) is an anti-tumor necrosis factor (TNF)-α antibody preparation known to be less immunogenic than infliximab (IFX) or adalimumab. Few reports on GLM in pediatric patients with ulcerative... -
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- Predictors of Small Bowel Transit Time for Capsule Endoscopy in Children with Inflammatory Bowel Disease
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Oka I, Funayama R, Shimizu H, Takeuchi I, Nojiri S, Shimizu T, Arai K
- KMID: 2544881
- Pediatr Gastroenterol Hepatol Nutr.
- 2023 Jul;26(4):181-192.
- doi: 10.5223/pghn.2023.26.4.181
Purpose: The development of assistive devices has allowed for the performance of capsule endoscopy in children. Anticipating the capsule’s transit time could affect the efficacy of the investigation and potentially... -
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- Clinical features of very early-onset inflammatory bowel disease in Japan: a retrospective single-center study
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Usami M, Takeuchi I, Kyodo R, Hirano Y, Kashiwagi K, Fujikawa H, Shimizu H, Kawai T, Arai K
- KMID: 2535821
- Intest Res.
- 2022 Oct;20(4):475-481.
- doi: 10.5217/ir.2021.00142
Background/Aims: Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed in patients younger than 6 years, is a challenge for pediatric gastroenterologists. Although there have been reports regarding VEO-IBD... -
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- Long-Term Durability of Infliximab for Pediatric Ulcerative Colitis: A Retrospective Data Review in a Tertiary Children's Hospital in Japan
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Shimizu H, Arai K, Takeuchi I, Minowa K, Hosoi K, Sato M, Oka I, Kaburaki Y, Shimizu T
- KMID: 2510620
- Pediatr Gastroenterol Hepatol Nutr.
- 2021 Jan;24(1):7-18.
- doi: 10.5223/pghn.2021.24.1.7
Purpose: The long-term efficacy and safety of infliximab (IFX) in children with ulcerative colitis (UC) have not been well-evaluated. Here, we reviewed the long-term durability and safety of IFX in... -
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- Epidemiological Study of Erythromycin-Resistant Streptococcus pyogenes From Korea and Japan by emm Genotyping and Multilocus Sequence Typing
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Takahashi , Arai K, Lee DH, Koh EH, Yoshida H, Yano H, Kaku M, Kim S
- KMID: 2373491
- Ann Lab Med.
- 2016 Jan;36(1):9-14.
- doi: 10.3343/alm.2016.36.1.9
BACKGROUND: We determined the epidemiological characteristics of erythromycin (EM)-resistant Streptococcus pyogenes (group A streptococci, GAS) strains isolated from Korea and Japan, using emm genotyping and multilocus sequence typing (MLST). METHODS: Clinical... -
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- Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan
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Yanagi T, Ushijima K, Koga H, Tomomasa T, Tajiri H, Kunisaki R, Isihige T, Yamada H, Arai K, Yoden A, Aomatsu T, Nagata S, Uchida K, Ohtsuka Y, Shimizu T
- KMID: 2465813
- Intest Res.
- 2019 Oct;17(4):476-485.
- doi: 10.5217/ir.2019.00027
BACKGROUND/AIMS: Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance... -
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- Phenotypic characteristics of pediatric inflammatory bowel disease in Japan: results from a multicenter registry
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Arai K, Kunisaki R, Kakuta F, Hagiwara Si, Murakoshi T, Yanagi T, Shimizu T, Kato S, Ishige T, Aomatsu T, Inoue M, Saito T, Iwama I, Kawashima H, Kumagai H, Tajiri H, Iwata N, Mochizuki T, Noguchi A, Kashiwabara T, Shimizu H, Suzuki Y, Hirano Y, Fujiwara T
- KMID: 2508568
- Intest Res.
- 2020 Oct;18(4):412-420.
- doi: 10.5217/ir.2019.00130
Background/Aims: There are few published registry studies from Asia on pediatric inflammatory bowel disease (IBD). Registry network data enable comparisons among ethnic groups. This study examined the characteristics of IBD... -
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