- Hemostatic Effects of High-Dose Aprotinin in Open Heart Operations
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Kim JT
- KMID: 1965025
- Ewha Med J.
- 1994 Sep;17(3):233-237.
- doi: 10.12771/emj.1994.17.3.233
Two groups of patients were studied to evaluate the hemostatic effects of high-does aprotinin in open heart operations. Aprotinin group patients(n=8) received aprotinin during entire surgical procedure. The other group... -
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- Anaphylactic Reaction after Aprotinin Reexposure: A case report
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Lee JH, Lee JY, Lim HS, Lee KN, Moon JI
- KMID: 2240086
- Korean J Anesthesiol.
- 1999 May;36(5):911-915.
- doi: 10.4097/kjae.1999.36.5.911
Aprotinin, a proteinase inhibitor, is known to significantly reduce blood loss during cardiac, thoracic and vascular surgery. Despite the wide use of this medication, there are only a few reports... -
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- The effect of aprotinin for hemostasis in open heart surgery
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Hong NS, Cha KT, Ahn WS, Hur Y, Kim BY, Lee JH
- KMID: 1686079
- Korean J Thorac Cardiovasc Surg.
- 1993 Oct;26(10):749-752.
No abstract available. -
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- Intraoperative Anaphylactoid Reaction Due to Aprotinin during Pediatric Open Heart Surgery
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Sim JY, Park JY, Kweon EH, Choi IC
- KMID: 1936364
- Korean J Anesthesiol.
- 2000 Feb;38(2):370-373.
- doi: 10.4097/kjae.2000.38.2.370
Aprotinin is a serine protease inhibitor that improves the hemostatic function and modulates the anti-inflammatory responses. Recently, aprotinin has been widely used in various surgical procedures including open heart... -
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- Result of Aprotinin and Fibronectin Treatment in Therapy Resistant Corneal Ulcer
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Kim EK, Kim HB, Yoon YD, Kim HL
- KMID: 2107646
- J Korean Ophthalmol Soc.
- 1990 Jun;31(6):783-788.
In two patients with chronic corneal ulcer, resistant to conventional therapy, analysis of tear fluid and observation of the corneal state were performed before and after treatment using autologous fibronectin... -
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- The Effects of Aprotinin of Experimental Corneal Burn in Rabbits
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Kim JC, Moon YS, Lee HK, Shyn KH
- KMID: 2147847
- J Korean Ophthalmol Soc.
- 1992 Nov;33(11):1043-1048.
Recently, many works to treat chronic corneal ulcer have been progressed. It has been reported that the Aprotinin, one of them, is serine protease inhibitor and is useful to treat... -
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- Effect of high-dose aprotinin on blood loss and need for blood transfusion after repeat open heart surgery
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Hong YW, Kim JK, Park CH
- KMID: 2236963
- Korean J Anesthesiol.
- 1994 Apr;27(4):373-380.
- doi: 10.4097/kjae.1994.27.4.373
The effect of the proteinase-inhibitor aprotinin on blood loss and homologous blood requirement in repeat mitral valve replacement whieh has a tendency of postoperative bleeding and increases requirement of homologous... -
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- A case of anaphylaxis induced by aprotinin during cardiac surgery
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Shin JH, Cho YS, Lee JC, Lim YJ, Lee EY, Lim MK, Ju YS, Yoo B, Moon HB
- KMID: 1563387
- J Asthma Allergy Clin Immunol.
- 2000 Feb;20(1):126-129.
No abstract available. -
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- Clinical Study of the Effect of Aprotinin for Hemostasis in Open Heart Surgery
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Jung SW, Kim JW
- KMID: 2062206
- Korean J Thorac Cardiovasc Surg.
- 1999 Apr;32(4):364-367.
BACKGROUND: The efficacy of the hemostasis of prophylactic aprotinin after cardiac valve replacement was evaluated from January 1994 to December 1996 at Pusan National University Hospital. MATERIAL AND METHOD: In... -
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- The Topical Effects of Antibiotics and Aprotinin in Experimental Pseudomonas Ketaititis
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Hong NS, Kim JC, Shyn KH
- KMID: 2123239
- J Korean Ophthalmol Soc.
- 1993 Mar;34(3):181-187.
The effects of the topically applied antibiotics and Aprotinin were evaluated in the experimentally induced pseudomonas aeruginosa keratitis in rabbits. 40 albino rabbits were used for this study and were... -
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- Two Cases of Acute Renal Failure Associated with Aprotinin
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Yun YS, Kwon SH, Park EK, Jeon JS, Noh HJ, Han DC, Jin SY
- KMID: 2253282
- Korean J Nephrol.
- 2008 May;27(3):383-388.
Aprotinin is a nonspecific serine protease inhibitor and antifibrinolytic agent. It has been used to control bleeding and reduce the amounts of transfusion during the perioperative period. There are few... -
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- Acute Renal Failure after Operation Associated with Aprotinin: Report of 3 cases
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Kim SC, Eom HS, Ok SY, Kim SI
- KMID: 2236685
- Korean J Anesthesiol.
- 2004 Nov;47(5):759-763.
- doi: 10.4097/kjae.2004.47.5.759
Aprotinin is a serine protease inhibitor and a powerful antifibrinolytic agent, derived from the inhibition of plasmin and kallikrein. Therefore, it is widely used in cardiopulmonary bypass surgery or major... -
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- Aprotinin Therapy for Cardiac Operation in Adult -Full dose regimen
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Jang UH, Oh TY, Kim MH
- KMID: 2062205
- Korean J Thorac Cardiovasc Surg.
- 1999 Apr;32(4):358-363.
BACKGROUND: Recently, many cardiac centers have been using aprotinin to reduce operative bleeding in cardiac operations using cardiopulmonary bypass. A variety of reports have confirmed the effectiveness of the drug... -
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- The Effect of Paratendinous Aprotinin Injection in Patients with Rotator Cuff Tendinitis
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Jung H, Seo JH, Ko MH, Sim YJ
- KMID: 2136462
- J Korean Acad Rehabil Med.
- 2008 Feb;32(1):56-61.
OBJECTIVE: To determine the therapeutic effect of paratendinous injection of aprotinin, a polyvalent inhibitor of inflammatory proteolytic enzyme, in patients with shoulder tendinitis. METHOD: Thirty patients with shoulder tendinitis diagnosed with... -
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- In Vitro Aprotinin Enhanced Anticoagulation Synergistically to Heparinized Blood on Thromboelastography
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Woo S, Sung KS, Hur CH, Kim MC, Cho KH
- KMID: 2091045
- Korean J Anesthesiol.
- 1997 Jan;32(1):74-78.
- doi: 10.4097/kjae.1997.32.1.74
BACKGROUND: Aprotinin is a potent, nonspecific broad serine protease inhibitor. It's inhibitory effects on intrinsic pathway of coagulation cascade can augment anticoagulation by heparin. This study designed to demonstrate augmented... -
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- Aprotinin Reduced Blood Loss in Spinal Deformity Surgery
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Suk SI, Kim JH, Kim SS, Kim JH, Cho BC, Jung NY
- KMID: 2186555
- J Korean Orthop Assoc.
- 2007 Jun;42(3):318-323.
- doi: 10.4055/jkoa.2007.42.3.318
PURPOSE: Complications are quite common in surgery to correct spinal deformities due to the long duration under anesthesia and massive blood loss. The aim of this study was to evaluate... -
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- Intraoperative Anaphylactoid Reaction Related to Aprotinin after Local Application of Fibrin Glue in Transsphenoid Surgery : A case report
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Jeon SS, Choi YW
- KMID: 2299169
- Korean J Anesthesiol.
- 2007 Jun;52(6):715-718.
- doi: 10.4097/kjae.2007.52.6.715
Recently fibrin glue, a hemostatic or adhesive material has been used worldwide in surgical procedures. There have been only limited numbers of reports on anaphylaxis following the topical use of... -
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- The Effect of Aprotinin for Reducing Blood Loss and Amount of Transfusion in Total Knee Arthroplasty
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Choi YJ, Hwang JK, Ahn HS, Bae EJ, Kim CH, Kim E
- KMID: 2182879
- J Korean Knee Soc.
- 2005 Dec;17(2):241-245.
PURPOSE: To evaluate the effect of Aprotinin in reducing postoperative blood loss and amount of transfusion in total knee arthroplasty. MATERIALS AND METHODS: In a prospective study, 100 patients undergoing bilateral... -
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- The Influence of High- and Low-Dose Aprotinin on Thromboelastography in Coronary Artery Bypass Grafting Surgery
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Han JS, Jung SM, Lee SY, Yoo ES, Suh CK, Min SK
- KMID: 2031610
- Korean J Anesthesiol.
- 2000 Oct;39(4):508-515.
- doi: 10.4097/kjae.2000.39.4.508
BACKGROUND: The protease inhibitor aprotinin reduces blood loss and homologous blood usage after a cardiac operation. The aim of the present study was to investigate the effect of low- and... -
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- Monitoring of Activated Coagulation Time with Kaolin vs. Celite Activator in Cardiac Surgical Patients with Aprotinin
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Kim JT, Sun K, Lee CS, Baek WK, Suh JW, Kim HT, Kim HS, Park HH, Kim KH
- KMID: 1987823
- Korean J Thorac Cardiovasc Surg.
- 1998 Sep;31(9):873-876.
BACKGROUND: High-dose aprotinin has been reported to enhance the anticoagulant effects of heparin during cardiopulmonary bypass ; hence, som authors have advocated reducing the dose of heparin in patients treated... -
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