J Korean Ophthalmol Soc.
1990 Jun;31(6):783-788.
Result of Aprotinin and Fibronectin Treatment in Therapy Resistant Corneal Ulcer
- Affiliations
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- 1Department of Ophthalmology, Yonsei University College of Medicine, Korea.
- 2Armed Forces Seoul District General Hospital, Korea.
Abstract
- In two patients with chronic corneal ulcer, resistant to conventional therapy, analysis of tear fluid and observation of the corneal state were performed before and after treatment using autologous fibronectin and aprotinin for the purpose of estimating the effect of treatment. The plasmin activity which was revealed before treatment was absent after treatment, and corneal reepithelialization was observed after treatment. We think the combined therapy with autologous fibronectin and aprotinin may be effective for the treatment of therapy-resistant chronic corneal ulcer.
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