- Apoptosis in Cardiovascular Diseases: Mechanism and Clinical Implications
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Kim NH, Kang PM
- KMID: 2225171
- Korean Circ J.
- 2010 Jul;40(7):299-305.
- doi: 10.4070/kcj.2010.40.7.299
Apoptosis is a tightly regulated, cell deletion process that plays an important role in various cardiovascular diseases, such as myocardial infarction, reperfusion injury, and heart failure. Since cardiomyocyte loss is... -
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- Running Title: Apoptotic Effect of Mycolactone in SCC15 Cells
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Kim JW, Song JC, Lee HK, Lee TY
- KMID: 1961184
- J Korean Assoc Oral Maxillofac Surg.
- 2001 Dec;27(6):511-518.
The effect of mycolactone, a recently reported apoptosis-inducing factor, was investigated in SCC15 oral squamous cell carcinoma (OSCC) cell line. Mycolactone rapidly induced cell death in OSCC cells in 2days,... -
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- Evidence of early involvement of apoptosis inducing factor-induced neuronal death in Alzheimer brain
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Lee JH, Cheon YH, Woo RS, Song DY, Moon C, Baik TK
- KMID: 1447450
- Anat Cell Biol.
- 2012 Mar;45(1):26-37.
- doi: 10.5115/acb.2012.45.1.26
Apoptosis inducing factor (AIF) has been proposed to act as a putative reactive oxygen species scavenger in mitochondria. When apoptotic cell death is triggered, AIF translocates to the nucleus, where... -
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- Effect of apoptosis on G361 cells by Cimicifuga rhizoma extract
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Choi BB, Kim GC, Hong JW, Park SR
- KMID: 2456840
- J Korean Acad Oral Health.
- 2019 Jun;43(2):72-77.
- doi: 10.11149/jkaoh.2019.43.2.72
OBJECTIVES: To investigate whether the cytotoxic effect of Cimicifuga rhizoma extract is associated with cell death in the human keratinocyte (HaCaT) and human melanoma cell lines (G361). METHODS: Apoptosis induced by... -
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- Role of Annexin A5 on Mitochondria-Dependent Apoptosis Induced by Tetramethoxystilbene in Human Breast Cancer Cells
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Hong M, Park N, Chun YJ
- KMID: 2170593
- Biomol Ther.
- 2014 Nov;22(6):519-524.
- doi: 10.4062/biomolther.2014.112
We have previously shown that 2,4,3',5'-tetramethoxystilbene (TMS), a trans-stilbene analogue, induces apoptosis in human cancer cells. However, the detailed mechanisms of mitochondria-dependent apoptosis induced by TMS are not fully understood.... -
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- Temporal Characteristics of Cytosolic Translocation of Mitochondrial Proteins in Permanent Distal Middle Cerebral Artery Occlusion Model of Rats
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Shin BW, Sung JH, Hong JT, Son BC, Lee SW, Park CK
- KMID: 2118517
- J Korean Neurosurg Soc.
- 2007 May;41(5):306-313.
OBJECTIVE: In permanent distal middle cerebral artery occlusion (pdMCAO) model of rats, the temporal order of subcellular translocation is not fully understood yet. We studied translocation sequence of cytochrome c... -
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- Sulindac-induced Apoptosis without Oligonucleosomal DNA Fragmentation in HT-29 Cells: Its Special References to Mitochondrial Pathway
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Park KJ, Kwon Y, Kim SH, Kim MC, Choi HJ, Kim YH, Cho SH, Jung GJ, Kim SH, Kwon HC
- KMID: 1566533
- J Korean Soc Coloproctol.
- 2004 Aug;20(4):191-198.
PURPOSE: This study was undertaken to reveal the molecular mechanism underlying sulindac-induced apoptosis in the human colon cancer cell line HT-29 (mutant p53). METHODS: Apoptosis was determined by using Hoechst... -
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- Effects of alpha-Lipoic Acid on Apoptotic Cell Death in Rat Hippocampus Following Transient Forebrain Ischemia-reperfusion Injury
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Ahn HC, Song JH, Kim KS, Yoo SJ
- KMID: 2331506
- J Korean Soc Emerg Med.
- 2007 Apr;18(2):134-142.
PURPOSE: The purpose of this study was to evaluate effect of alpha-lipoic acid on apoptotic cell death in rat hippocampal neuron following transient forebrain ischemia-reperfusion (I/R) injury. METHODS: The four-vessel occlusion... -
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- Arsenic Trioxide Induces A poptosis in Human Colorectal Adenocarcinoma HT-29 Cells Through ROS
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Cha Y, Park DW, Lee CH, Baek SH, Kim SY, Kim JR, Kim JH
- KMID: 2166094
- Cancer Res Treat.
- 2006 Feb;38(1):54-60.
PURPOSE: Treatment with arsenic trioxide (As2O3) results in a wide range of cellular effects that includes induction of apoptosis, inhibition of cell growth, promotion or inhibition of cellular differentiation, and... -
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- Induction of Melanoma Cell-Selective Apoptosis Using Anti-HER2 Antibody-Conjugated Gold Nanoparticles
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Jeon HJ, Choi BB, Park KH, Hwang DS, Kim UK, Kim GC
- KMID: 2446955
- Yonsei Med J.
- 2019 Jun;60(6):509-516.
- doi: 10.3349/ymj.2019.60.6.509
PURPOSE: This study was conducted to verify the induction and mechanism of selective apoptosis in G361 melanoma cells using anti-HER2 antibody-conjugated gold nanoparticles (GNP-HER2). MATERIALS AND METHODS: Following GNP-HER2 treatment of... -
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- Protective Effect of Minocycline Against Cisplatin-induced Ototoxicity
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Lee CK, Shin JI, Cho YS
- KMID: 2166447
- Clin Exp Otorhinolaryngol.
- 2011 Jun;4(2):77-82.
OBJECTIVES: Cisplatin, a widely used chemotherapeutic agent, has serious side effects, including nephrotoxicity and ototoxicity. Minocycline is a semisynthetic second-generation tetracycline that exerts anti-inflammatory and neuroprotective effects. The purpose of... -
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- Induction of Selective Cell Death of Oral Squamous Carcinoma Cells by Integrin alpha2 Antibody and EGFR Antibody
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Choi YS, Kim GC, Yoon S, Hwang DS, Kim CH, Jeon YC, Byun JH, Shin SH, Kim UK
- KMID: 2004433
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2013 May;35(3):143-154.
PURPOSE: This study was to find efficacy of integrin alpha2 (alpha2) and epidermal growth factor receptor (EGFR) as tumor marker of oral squamous cell carcinoma (SCC) and clarify the selective... -
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