- Chemotherapy induced liver abnormalities: an imaging perspective
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Sharma A, Houshyar R, Bhosale P, Choi JI, Gulati R, Lall C
- KMID: 2069771
- Clin Mol Hepatol.
- 2014 Sep;20(3):317-326.
- doi: 10.3350/cmh.2014.20.3.317
Treating patients undergoing chemotherapy who display findings of liver toxicity, requires a solid understanding of these medications. It is important for any clinician to have an index of suspicion for... -
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- Four cases of therapy-related leukemia
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Hur M, Lee DS, Shin HY, Ahn HS, Kim BK, Cho HI
- KMID: 646314
- J Korean Med Sci.
- 1999 Jun;14(3):327-329.
- doi: 10.3346/jkms.1999.14.3.327
Combination chemotherapy and radiation therapy have contributed to the successful treatment of various cancer patients. But the development of second malignancies is an inevitable complication of long-term cytotoxic treatment. The most serious and... -
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- Ifosfamide-induced Fanconi syndrome with diabetes insipidus
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Leem AY, Kim HS, Yoo BW, Kang BD, Kim MH, Rha SY, Kim HS
- KMID: 1792043
- Korean J Intern Med.
- 2014 Mar;29(2):246-249.
- doi: 10.3904/kjim.2014.29.2.246
Ifosfamide-induced Fanconi syndrome is a rare complication that typically occurs in young patients due to a cumulative dose of ifosfamide > 40-60 g/m2, a reduction in kidney mass, or concurrent... -
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- Is the Low-Thalidomide Dose MPT Regimen Beneficial?
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Min CK
- KMID: 1729241
- Korean J Intern Med.
- 2011 Dec;26(4):400-402.
- doi: 10.3904/kjim.2011.26.4.400
No abstract available. -
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- Clinical Result of Prolonged Primary Chemotherapy in Retinoblastoma Patients
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Kim JH, Yu YS, Khwarg SI, Choi HS, Shin HY, Ahn HS
- KMID: 754340
- Korean J Ophthalmol.
- 2003 Jun;17(1):35-43.
- doi: 10.3341/kjo.2003.17.1.35
This study evaluated the effects of prolonged primary chemotherapy in retinoblastoma. The data for 27 eyes in 22 children who were treated for retinoblastoma with up to 13 cycles of... -
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- ANCA-Negative Wegener's Granulomatosis with Multiple Lower Cranial Nerve Palsies
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Kim SH, Park J, Bae JH, Cho MS, Park KD, Jeong JH
- KMID: 1777672
- J Korean Med Sci.
- 2013 Nov;28(11):1690-1696.
- doi: 10.3346/jkms.2013.28.11.1690
Wegener's granulomatosis (WG) is a systemic vasculitis affecting small and medium-sized vessels with granulomatous formation. Though it is known for respiratory tract and kidney involvement, neurologic manifestation has been also... -
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- Validation of the Effectiveness and Safety of Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas: 10-year Experience of a Single Institution
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Joo JD, Kim H, Kim YH, Han JH, Kim CY
- KMID: 2351109
- J Korean Med Sci.
- 2015 Nov;30(11):1597-1603.
- doi: 10.3346/jkms.2015.30.11.1597
This study was performed to validate the effectiveness and safety of concurrent chemoradiotherapy and adjuvant therapy with temozolomide for newly diagnosed glioblastoma multiforme as a standard treatment protocol. Between 2004... -
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- Toxicity Profile of Temozolomide in the Treatment of 300 Malignant Glioma Patients in Korea
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Bae SH, Park MJ, Lee MM, Kim TM, Lee SH, Cho SY, Kim YH, Kim YJ, Park CK, Kim CY
- KMID: 1789958
- J Korean Med Sci.
- 2014 Jul;29(7):980-984.
- doi: 10.3346/jkms.2014.29.7.980
This study evaluated the toxicity profiles of temozolomide in the treatment of malignant glioma as either concurrent or adjuvant chemotherapy. We retrospectively reviewed the medical records of 300 malignant glioma... -
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- The possible cost effectiveness of peripheral blood stem cell mobilization with clophosphamide and the late addition of G-CSF
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Min YJ, Kim SW, Suh C, Park J, Kim HJ, Kim JG, Kim TW, Lee JH, Kim SB, Lee KH, Lee JS, Kim WK, Kim SH
- KMID: 1731233
- J Korean Med Sci.
- 2000 Feb;15(1):49-52.
- doi: 10.3346/jkms.2000.15.1.49
The purpose of this study was to develop a cost-effective protocol for the mobilization of peripheral blood stem cells (PBSC) in patients with malignancy. Thirty consecutive patients were randomized to... -
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- Visual Prognosis of Retinoblastoma in the Posterior Pole Treated with Primary Chemotherapy Plus Local Treatments
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Kim JM, Kim JH, Kim SJ, Park KD, Shin HY, Ahn HS, Yu YS
- KMID: 1769088
- Korean J Ophthalmol.
- 2010 Dec;24(6):347-352.
- doi: 10.3341/kjo.2010.24.6.347
PURPOSE: To evaluate the visual outcomes of retinoblastoma in the posterior pole (RBPP) treated with chemotherapy plus local treatments and to address the prognostic factors that influence such outcomes. METHODS:... -
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- Temozolomide-Associated Bronchiolitis Obliterans Organizing Pneumonia Successfully Treated with High-Dose Corticosteroid
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Kim TO, Oh IJ, Kang HW, Chi SY, Ban HJ, Kwon YS, Kim KS, Kim YI, Lim SC, Kim YC
- KMID: 2157909
- J Korean Med Sci.
- 2012 Apr;27(4):450-453.
- doi: 10.3346/jkms.2012.27.4.450
Temozolomide is an oral alkylating agent with clinical activity against glioblastoma multiforme (GM). It is generally well-tolerated and has few pulmonary side effects. We report a case of temozolomide-associated brochiolitis... -
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- DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells
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Zhou D, Wan Y, Xie D, Wang Y, Wei J, Yan Q, Lu P, Mo L, Xie J, Yang S, Qi X
- KMID: 2155436
- Exp Mol Med.
- 2015 Sep;47(9):e182.
- doi: 10.1038/emm.2015.57
Although methyltransferase has been recognized as a major element that governs the epigenetic regulation of the genome during temozolomide (TMZ) chemotherapy in glioblastoma multiforme (GBM) patients, its regulatory effect on... -
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- Prediction of Response to Concurrent Chemoradiotherapy with Temozolomide in Glioblastoma: Application of Immediate Post-Operative Dynamic Susceptibility Contrast and Diffusion-Weighted MR Imaging
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Lee EK, Choi SH, Yun TJ, Kang KM, Kim TM, Lee SH, Park CK, Park SH, Kim IH
- KMID: 2344290
- Korean J Radiol.
- 2015 Dec;16(6):1341-1348.
- doi: 10.3348/kjr.2015.16.6.1341
OBJECTIVE: To determine whether histogram values of the normalized apparent diffusion coefficient (nADC) and normalized cerebral blood volume (nCBV) maps obtained in contrast-enhancing lesions detected on immediate post-operative MR imaging... -
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- Hexamethylmelamine as Consolidation Treatment for Patients with Advanced Epithelial Ovarian Cancer in Complete Response after First-Line Chemotherapy
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Kwon YS, Nam JH, Kim DY, Suh DS, Kim JH, Kim YM, Kim YT
- KMID: 1779203
- J Korean Med Sci.
- 2009 Aug;24(4):679-683.
- doi: 10.3346/jkms.2009.24.4.679
The aim of this study was to assess the efficacy of consolidation therapy with hexamethylmelamine (HMM) in patients with advanced epithelial ovarian cancer (EOC). Patients treated at our hospital between... -
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- Temozolomide Chemotherapy in Patients with Recurrent Malignant Gliomas
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Yang SH, Kim MK, Lee TK, Lee KS, Jeun SS, Park CK, Kang JK, Kim MC, Hong YK
- KMID: 2157831
- J Korean Med Sci.
- 2006 Aug;21(4):739-744.
- doi: 10.3346/jkms.2006.21.4.739
Numerous studies have demonstrated the clinical activity of temozolomide, a second-generation alkylating agent, against malignant brain tumors, however, its activity has not been reported in an Asian population. This study... -
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- The effect of cyclophosphamide on Fas-mediated apoptosis
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Lee JH, Park JH, Yang MH
- KMID: 1038387
- J Korean Med Sci.
- 1997 Jun;12(3):185-189.
- doi: 10.3346/jkms.1997.12.3.185
Fas is a cell surface protein that can mediate apoptosis and belongs to the tumor necrosis factor (TNF) receptor family. Anti-Fas antibody induces apoptotic cell death in... -
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- A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma
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Chang HJ, Lee JH, Do YR, Bae SH, Lee JL, Nam SH, Yoon SS, Bang SM
- KMID: 1729242
- Korean J Intern Med.
- 2011 Dec;26(4):403-409.
- doi: 10.3904/kjim.2011.26.4.403
BACKGROUND/AIMS: The clinical efficacy and safety of a three-drug combination of melphalan, prednisone, and thalidomide were assessed in patients with multiple myeloma who were not candidates for high-dose therapy as... -
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- Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells
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Kang DW, Lee JY, Oh DH, Park SY, Woo TM, Kim MK, Park MH, Jang YH, Min DS
- KMID: 756211
- Exp Mol Med.
- 2009 Sep;41(9):678-685.
- doi: 10.3858/emm.2009.41.9.074
In spite of the importance of phospholipase D (PLD) in cell proliferation and tumorigenesis, little is known about the molecules regulating PLD expression. Thus, identification of small molecules inhibiting PLD... -
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- Triptolide inhibits ovarian cancer cell invasion by repression of matrix metalloproteinase 7 and 19 and upregulation of E-cadherin
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Zhao H, Yang Z, Wang X, Zhang X, Wang M, Wang Y, Mei Q, Wang Z
- KMID: 1401755
- Exp Mol Med.
- 2012 Nov;44(11):633-641.
Triptolide, a compound extracted from the traditional Chinese medicine preparation of Tripterygium wilfordii Hook F., has been reported to have anti-inflammatory and anti-cancer activities. However, its effect on ovarian cancer... -
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- High Dose Therapy Followed by Autologous Peripheral Blood Stem Cell Transplantation as a First Line Treatment for Multiple Myeloma: a Korean Multicenter Study
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Bang SM, Cho EK, Suh C, Yoon SS, Seong CM, Cho KS, Kang YG, Park S, Ahn MJ, Park YS, Oh D, Kim HC, Jung CW, Kim S, Lee JH
- KMID: 1130037
- J Korean Med Sci.
- 2003 Oct;18(5):673-678.
- doi: 10.3346/jkms.2003.18.5.673
We conducted a phase II multicenter trial to estimate the response and survival of patients with newly diagnosed multiple myeloma to high dose melphalan therapy followed by autologous peripheral blood... -
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