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Effects of dexamethasone and DHEA on the responses of rat cerebral cortical astrocytes to lipopolysaccharide and antimycin A

Choi SH, Kim HG, Kim CK, Park NH, Choi DH, Shim IS, Chun BG

  • KMID: 1554126
  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):127-135.
As part of a study on the effects of dexamethasone and dehydroepiandrosterone (DHEA) on the biological roles of astrocytes in brain injury, this study evaluated the effects of dexamethasone and DHEA on the...
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Effects of dexamethasone and DHEA on the changes of glutamate and polyamine uptake in rat astrocytes by lipopolysaccharide and antimycin A

Choi SH, Lee B, Shin KH, Min BH, Chun YS, Chun BG

  • KMID: 1554128
  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):137-146.
Interactions among dexamethasone, dehydroepiandrosterone (DHEA), lipopolysaccharide (LPS), and antimycin A on the glutamate uptake and the polyamine uptake were investigated in primary cultures of rat cerebral cortical astrocytes to examine the effects of...
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The Neuroprotective Effects of Carnosine in Early Stage of Focal Ischemia Rodent Model

Park HS, Han KH, Shin JA, Park JH, Song KY, Kim DH

OBJECTIVE: This study was conducted to elucidate neuroprotective effect of carnosine in early stage of stroke. METHODS: Early stage of rodent stroke model and neuroblastoma chemical hypoxia model was established by...
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Effects of Mitochondrial Reactive Oxygen Species on Neuronal Excitability in Rat Spinal Substantia Gelatinosa Neurons

Lee HI, Park AR, Chun SW

  • KMID: 2009495
  • Int J Oral Biol.
  • 2012 Mar;37(1):17-23.
Recent studies indicate that reactive oxygen species (ROS) are critically involved in persistent pain primarily through spinal mechanisms, and that mitochondria are the main source of ROS in the spinal...
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Mitochondrial dysfunction reduces the activity of KIR2.1 K⁺ channel in myoblasts via impaired oxidative phosphorylation

Woo J, Kim HJ, Nam YR, Kim YK, Lee EJ, Choi I, Kim SJ, Lee W, Nam JH

Myoblast fusion depends on mitochondrial integrity and intracellular Ca²⁺ signaling regulated by various ion channels. In this study, we investigated the ionic currents associated with [Ca²⁺]i regulation in normal and...
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Ischemia-responsive Protein(irp94) Gene Expression in a Neuronal Cell Culture Model of Ischemia

Kim SH, Yang YM, Ha YR, Chung SP, Yoo IS, Kim IB

  • KMID: 2100588
  • J Korean Soc Emerg Med.
  • 2001 Sep;12(3):201-206.
BACKGROUND: The ischemia responsive protein 94 kDa(irp94) gene belongs to the heat shock protein 110 family and was isolated in 1999 from rat brain by transiently induced forebrain ischemia. The...
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Mitochondrial Complexes I and II Are More Susceptible to Autophagy Deficiency in Mouse beta-Cells

Kim MJ, Choi OK, Chae KS, Kim MK, Kim JH, Komatsu M, Tanaka K, Lee H, Chung SS, Kwak SH, Cho YM, Park KS, Jung HS

BACKGROUND: Damaged mitochondria are removed by autophagy. Therefore, impairment of autophagy induces the accumulation of damaged mitochondria and mitochondrial dysfunction in most mammalian cells. Here, we investigated mitochondrial function and...
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