- Detection Of Antibodies To Ena In The Systemic Lupus Erythematosus By Immunoblotting: A Cornparision Of Irnmunoblotting And Double Immunodiffusion
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Park SH, Lee SH, Cho CS, Kim HY
- KMID: 2025496
- J Korean Rheum Assoc.
- 1995 Jan;2(1):34-41.
OBJECTIVE: Systemic Lupus Erythematosus(SLE) is characterized by various autoantibodies to a variety of nuclear antigens. Certain extractable nuclear antigens(ENA) have been served as extremly useful aids in differentiation of clinical... -
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- Detection of Anti-Extractable Nuclear Antigens in Patients with Systemic Rheumatic Disease via Fluorescence Enzyme Immunoassay and Its Clinical Utility
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Oh J, Park Y, Lee KA, Kim HS
- KMID: 2466338
- Yonsei Med J.
- 2020 Jan;61(1):73-78.
- doi: 10.3349/ymj.2020.61.1.73
PURPOSE: Testing for autoantibodies to extractable nuclear antigens (ENAs) plays an important role in the diagnosis and management of systemic rheumatic disease. Currently, no gold standard tests are available for... -
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- Autoimmune Responses in Severe Asthma
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Mukherjee , Nair P
- KMID: 2418042
- Allergy Asthma Immunol Res.
- 2018 Sep;10(5):428-447.
- doi: 10.4168/aair.2018.10.5.428
Asthma and autoimmune diseases both result from a dysregulated immune system, and have been conventionally considered to have mutually exclusive pathogenesis. Autoimmunity is believed to be an exaggerated Th1 response,... -
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- A Comparative Study for the Titer of IgG Autoantibodies in the Serum and Urine of Patients with Bullous Pemphigoid, Epidermolysis Bullosa Acqusita, and Pemphigus
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Park JH, Lee CW
- KMID: 1604666
- Korean J Dermatol.
- 2002 Apr;40(4):399-404.
BACKGROUND: The immunoglobulins can be detected in the urine in normal people without any renal disease. According to recent articles, it is known that autoantibodies of IgG, which share the... -
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- Degree of Agreement between Phadia EliA ENA and Euroimmun line Immunoassay; Comparison of Two Methods to Evaluate the Ability to Detect ENA Antibodies
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Hwang HY
- KMID: 1993583
- Kosin Med J.
- 2012 Jun;27(1):25-30.
- doi: 10.7180/kmj.2012.27.1.25
OBJECTIVES: The purpose of this study is to compare newly developed assay for identification of ENA antibody, Phadia EliA ENA with Euroimmun line immunoassay by analyzing the degree of agreement... -
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- The Pattern of Epidermal Immune Deposits in Patients with High - Titer Anti - Ro Positive Lupus Erythematosus
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Lee CW, Jun JH
- KMID: 1891511
- Korean J Dermatol.
- 1996 Oct;34(5):784-789.
BACKGROUND: Antibodies to Bo antigen are present in most patients with subacute cutaneous lupus erythematosus and in about 50% of Korean patients with systemic lupus erythematosus (LE). However, the pattern... -
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- CD72 is a Negative Regulator of B Cell Responses to Nuclear Lupus Self-antigens and Development of Systemic Lupus Erythematosus
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Tsubata T
- KMID: 2438909
- Immune Netw.
- 2019 Feb;19(1):e1.
- doi: 10.4110/in.2019.19.e1
Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease characterized by production of autoantibodies to various nuclear antigens and overexpression of genes regulated by IFN-I called IFN signature. Genetic... -
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- Agreement of three commercial anti-extractable nuclear antigen tests: EUROASSAY Anti-ENA Profile, Polycheck Autoimmune Test and FID(IS) Connective Profile
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Kim N, Kim IS, Chang CL, Kim HH, Lee EY
- KMID: 2442541
- Kosin Med J.
- 2018 Dec;33(3):307-317.
- doi: 10.7180/kmj.2018.33.3.307
BACKGROUND: Detection of antibodies to extractable nuclear antigens (ENAs) is needed for the diagnosis in systemic autoimmune diseases. In this study, we compared three reagents using line immunoblot assay (LIA)... -
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- Detection of Autoantibodies for Extractable Nuclear Antigens by LG Immunoblot Kit
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Chae JD, Oh HB, Lee CG, Yoo B, Sohn MJ, Yoo SB
- KMID: 2226055
- Korean J Clin Pathol.
- 2002 Feb;22(1):34-41.
BACKGROUND: Identification of antibodies recognizing extractable nuclear antigens (ENAs) is use-ful in the diagnosis and characterization of a variety of connective tissue diseases. Recently, LG ENA Immunoblot (LGCI, Seoul, Korea)... -
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- Clinical Significance of Cytoplasmic Staining in Antinuclear Antibody Tests Using HEp-2 Cells
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Baek HM, Nahm CH, Song JS, Park W, Moon YS, Kim JJ
- KMID: 1889885
- Korean J Lab Med.
- 2003 Dec;23(6):415-419.
BACKGROUND: Cytoplasmic stainings in antinuclear antibody tests using HEp-2 cells are usually undetermined and the significance has not been fully understood until now. Hence, we evaluated their clinical characteristics and... -
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- Systemic lupus erythematosus
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Kim KN
- KMID: 2279448
- Korean J Pediatr.
- 2007 Dec;50(12):1180-1187.
- doi: 10.3345/kjp.2007.50.12.1180
Systemic lupus erythematosus (SLE) is an episodic, multi-system, autoimmune disease characterized by widespread inflammation of blood vessels and connective tissues and by the presence of antinuclear antibodies (ANAs), especially antibodies... -
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- Detection of Anti-ENA and anti-dsDNA Antibodies Using Line Immunoassay in Systemic Autoimmune Diseases
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Kim JM, Ihm CH, Sin DH, Ihm MK, Sim SC
- KMID: 1781567
- Korean J Lab Med.
- 2008 Oct;28(5):353-361.
- doi: 10.3343/kjlm.2008.28.5.353
BACKGROUND: Detection of antibodies to extractable nuclear antigens (ENAs) and dsDNA is needed for the diagnosis of and predicting prognosis in systemic autoimmune diseases. Recently introduced line immunoassay (LIA) has... -
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- A Hemolytic Transfusion Reaction due to Anti-Ku Antibody in a Patient with Knull Phenotype: The First Case in Korea
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Kang MG, Lim YA, Lee KM
- KMID: 1096976
- Korean J Lab Med.
- 2009 Jun;29(3):238-242.
- doi: 10.3343/kjlm.2009.29.3.238
Knull phenotype completely lacks all Kell system antigens. Anti-Ku antibody is seen in immunized persons with Knull phenotype by transfusion or pregnancy. It can cause a fatal hemolytic transfusion reaction.... -
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- SIRT1 promotes DNA repair activity and deacetylation of Ku70
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Jeong J, Juhn K, Lee H, Kim SH, Min BH, Lee KM, Cho MH, Park GH, Lee KH
- KMID: 1103676
- Exp Mol Med.
- 2007 Feb;39(1):8-13.
Human SIRT1 controls various physiological responses including cell fate, stress, and aging, through deacetylation of its specific substrate protein. In processing DNA damage signaling, SIRT1 attenuates a cellular apoptotic response... -
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- Decreased expression of DNA repair proteins Ku70 and Mre11 is associated with aging and may contribute to the cellular senescence
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Ju YJ, Lee KH, Park JE, Yi YS, Yun MY, Ham YH, Kim TJ, Choi HM, Han GJ, Lee JH, Lee J, Han JS, Lee KM, Park GH
- KMID: 1115947
- Exp Mol Med.
- 2006 Dec;38(6):686-693.
The gradual loss of telomeric DNA can contribute to replicative senescence and thus, having longer telomeric DNA is generally considered to provide a longer lifespan. Maintenance and stabilization of telomeric... -
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