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Preferential Expression of CD44 in Thyroid Papillary Carcinoma

Kim JY, Yoo J, Cho H

  • KMID: 1725819
  • Korean J Pathol.
  • 2001 Aug;35(4):314-318.
BACKGROUND: Papillary carcinoma is one of the most common malignant thyroid tumors and an important prognostic factor is the lymph node status. CD44 is a cell adhesion molecule and is...
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The significance of CD44 variants expression in colorectal cancer and its regional lymph nodes

Chun SY, Bae OS, Kim JB

CD44 is a cell adhesion molecule with numerous isoforms created by mRNA alternative splicing. Expression of CD44 variants has been suggested to play a potential role in tumor progression and...
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Clinicopathological Significance of Invasive Ductal Carcinoma with High Prevalence of CD44(+)/CD24(-/low) Tumor Cells in Breast Cancer

Sung JY, Kim GY, Park YK, Lee J, Kim YW, Lim SJ

  • KMID: 2277577
  • Korean J Pathol.
  • 2010 Aug;44(4):390-396.
BACKGROUND: Epithelial tumor cells with a CD44(+)/CD24(-/low) immunoprofile may have the ability to cause breast cancer. We studied these cells and their clinicopathological significance. METHODS: The clinicopathologic findings of 100 invasive...
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CD44 and MMP14 Expression Associated with WHO Grade of the Astrocytoma and the Prognostic Implications

Myung J, Jang B, Park HS, Yon W, Lee HJ, Park SH

  • KMID: 2277621
  • Korean J Pathol.
  • 2010 Feb;44(1):35-41.
BACKGROUND: CD44 is a cell surface receptor that has been implicated in tumor cell invasion and metastasis in a range of tumors of various organs, including breast, ovary, colon, lung,...
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Expressions of CD44s Is Associated with the Expression of Cyclooxygenase-2 in Non-Small Cell Lung Cancers

Lim SJ, Kim HJ, Kim JY, Park K

  • KMID: 1593156
  • Korean J Pathol.
  • 2006 Feb;40(1):17-23.
BACKGROUND: The overexpression of Cox-2 in tumors is important for tumor invasion, angiogenesis, resistance to apoptosis and the suppression of host immunity. Moreover, a tumor's CD44 expression plays an important...
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Expression of CD44 Isoforms and Its Significance in Renal Cell Carcinoma

Yoon GS, Hong HY, Kim TS

  • KMID: 1855947
  • Korean J Pathol.
  • 2005 Aug;39(4):251-257.
Background : CD44 is a transmembranous glycoprotein that participates in cell-cell and cell-matrix interactions, and it also contributes to cell migration. In vitro studies have suggested that the expression of...
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CD44s and CD44v6 Are Predominantly Expressed in the Non-germinal Center B-Cell-like Type of Diffuse Large B-Cell Lymphomas

Min KW, Oh YH, Park CK, Lim SD, Kim WS

  • KMID: 1979061
  • Korean J Pathol.
  • 2011 Dec;45(6):589-595.
BACKGROUND: CD44 protein is known as a homing cellular adhesion molecule that is linked to diverse cellular functions such as adhesion, migration and invasion, which are all important in cancer...
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CD44 Standard and Variants Expression in Keratinocytic Tumor

Ko JW, Suh KS, Kim ST

  • KMID: 2303242
  • Korean J Dermatol.
  • 2000 Jul;38(7):880-887.
BACKGROUND: The CD44 antigen is a widely distributed cell surface glycoprotein implicated in multiple physiological cellular functions including cell-cell adhesion, cell-substrate interaction and cell activation. In the skin, CD44 is...
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CD44 Disruption Attenuates Murine Hepatic Ischemia/Reperfusion Injury

Kim MS, Lee KH, Lee WM, Jun JH, Kim DH

Neutrophil adhesion and migration are critical in hepatic ischemia/reperfusion (I/R) injury. Despite very strong preclinical data, recent clinical trials failed to show a protective effect of anti-adhesion therapy in reperfusion...
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The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study

Huang J, Zhang D, Xie F, Lin D

Increasing evidence suggests that cancer stem cells (CSCs) are responsible for tumor initiation and maintenance. Additionally, it is becoming apparent that cyclooxygenase (COX) signaling is associated with canine mammary tumor...
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Identification of CD44 splice variant in Korean colorectal cancers and cell lines

Suh SI, Baek WK, Park JW, Bae OS, Suh MH, Choe BK

CD44 is a glycoprotein expressed in a wide variety of cell types. Recently expression of some alternatively-spliced variants of CD44 transcripts (CD44v) has been suggested to play a potential role...
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Molecular genetic characterization of alternatively spliced CD44 transcripts in human stomach carcinoma

Kim YS, Chi SG, Kim YW, Park YK, Yoon C

CD44 is a member of cell surface glycoproteins which are involved in cell-matrix adhesion and tumor metastasis. Certain types of tumors express complex CD44 isoforms generated by alternative splicing...
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Increased expression of osteopontin in the spinal cords of Lewis rats with experimental autoimmune neuritis

Moon C, Shin T

  • KMID: 1093622
  • J Vet Sci.
  • 2004 Dec;5(4):289-293.
To investigate the pattern of expression of osteopontin (OPN) in tissues of the central nervous system (CNS) responding to peripheral immunological stimulation, the expression of OPN was studied in the...
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Multipotentiality of CD34- Cells Extracted from Human Cord Blood

Kim SH, Yang IH, Kim HO, Lee JW

  • KMID: 2399083
  • J Korean Orthop Assoc.
  • 2004 Jun;39(3):315-322.
PURPOSE: We evaluated the differentiation potential of CD34-cells expanded from human cord blood into several differentiated cells, namely, osteoblasts, chondrocytes and adipocytes. MATERIALS AND METHODS: CD34- cells, extracted from cord...
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Detection of Epstein-Barr Virus by PCR and Expression of LMP1, p53, CD44 in Gastric Cancer

Lee MA, Hong YS, Kang JH, Lee KS, You JY, Lee KY, Park CH

  • KMID: 759684
  • Korean J Intern Med.
  • 2004 Mar;19(1):43-47.
BACKGROUND: Epstein-Barr virus (EBV) is associated with various lymphoproliferative disorders and nasopharyngeal carcinoma. Recently, some gastric cancer cells were observed to contain the EBV sequence. We detected EBV in gastric...
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Immunohistochemical Analysis of CD44s and CD44v6 in Endometriosis and Adenomyosis: Comparison with normal, hyperplastic, and malignant endometrium

Lin ZH, Cho SJ, Jeong HJ, Kim HK, Kim IS

The expression patterns of CD44s and CD44v6 were immunohistochemically compared with those of normal, hyperplastic and malignant endometrium. In normal endometria (n=37), endometrioses (n=46) and adenomyoses (n=20), the surface and...
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Expression of the Transmembrane Glycoprotein CD44s Is Potentially an Independent Predictor of Recurrence in Hepatocellular Carcinoma

Ryu HS, Park SH, Lee KB, Shin E, Jang JJ

  • KMID: 2135094
  • Gut Liver.
  • 2011 Jun;5(2):204-209.
BACKGROUND/AIMS: Cluster differentiation 44 standard isoform (CD44s) is a transmembrane glycoprotein. CD44s is a known prognostic factor in various cancers, due to its involvement in tumor cell growth, invasion and...
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Detection of Malignant Cells in Pleural Fluid or Ascites by CD44v8-10/CD44v10 competitive RT-PCR

Ahn MJ, Noh YH, Yoon HJ, Yang SC, Sohn JW, Choi JH, Lee YY, Choi IY, Kim IS, Lee YS, Park CK

  • KMID: 759532
  • Korean J Intern Med.
  • 2001 Mar;16(1):30-35.
BACKGROUND: CD44 is a cell surface adhesion molecule which has been implicated in various biologic functions as lymphocyte homing and activation, cellular migration and extracellular matrix adhesion. Over-expression of CD44v8-...
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Up-regulation of prothymosin alpha in THP-1 cells infected with Mycobacterium tuberculosis

Song HY, Jang KS, Byoun HS, Lee SJ, Kim JK, Choe YK, Ko KK

  • KMID: 2146888
  • J Korean Soc Microbiol.
  • 2000 Apr;35(2):149-157.
Mycobacterium tuberculosis is capable of growing and survival within macrophage. The purpose of this study was to identify the genes regulated by infection of mycobacteria in human monocytic THP-1 cells. We used the...
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Homing-Associated Cell Adhesion Molecules and Cell Cycle Status on the Nucleated Cells in the Bone Marrow, Mobilized Peripheral Blood and Cord Blood

Lee YH, Lee YA, Noh KT, Kim KH, Han JY, Seo SY, Kwon HC, Kim JS, Kim HJ

Homing-associated cell adhesion molecules (H-CAM) on the CD34+ cells play an important role for the engraftment process following hematopoietic stem cell transplantation (HSCT). However, it seems that not only CD34+...
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