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Initial Steps to Prevent Nonsteroidal Anti-Inflammatory Drug- or Aspirin-Induced Enteropathy: Long-Term Outcome Data

Lee IS, Cho YK

No abstract available.
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Non-steroidal Anti-inflammatory Drugs and Helicobacter pylori in Upper Gastrointestinal Bleeding

Lee YC

  • KMID: 1113362
  • Korean J Gastroenterol.
  • 2004 Sep;44(3):172-176.
No abstract available.
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The Effects of Etodolac, Nimesulid and Naproxen Sodium on the Frequency of Sister Chromatid Exchange after Enclused Third Molars Surgery

Koseoglu B, Ozturk S, Kocak H, Palanduz S, Cefle K

PURPOSE: Non-steroidal anti-inflammatory drugs (NSAID) are frequently used in oral surgical procedures in dentistry. The evaluation of the frequency of sister chromatid exchange (SCE) is accepted as a reliable cytogenetic...
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NSAID-induced Gastroenteropathy

Kim JW

  • KMID: 1767617
  • Korean J Gastroenterol.
  • 2008 Sep;52(3):134-141.
Non-steroidal anti-inflammatory drugs (NSAIDs) are used for the management of various conditions, such as pain, fever, inflammation, cancer, or cardiovascular diseases. These drugs may induce injury throughout the gastrointestinal tract....
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Guidelines of Prevention and Treatment for NSAID-related Peptic Ulcers

Lee JH, Lee YC, Jeon SW, Kim JW, Lee SW, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association of Gastroenterology

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications in Korea. Gastrointestinal toxicity, including peptic ulcer, is a common adverse effect of NSAIDs. Risk factors for NSAID-related peptic...
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The Effect of Non-steroidal Anti-inflammatory Drugs in Upper Gastrointestinal Bleeding

Lee SW, Kim HY, Park SH, Hahm KB, Bae JM, Jung HC, Kim JH

  • KMID: 1113292
  • Korean J Gastroenterol.
  • 2004 Jul;44(1):13-18.
BACKGROUND/AIMS: To evaluate the association between non-steroidal anti-inflammatory drugs (NSAIDs) use and upper gastrointestinal (UGI) bleeding, we performed a case-control study at the six University affiliated hospitals for one...
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Does Helicobacter pylori Exacerbate Gastric Mucosal Injury in Users of Nonsteroidal Anti-Inflammatory Drugs? A Multicenter, Retrospective, Case-Control Study

Kono Y, Okada H, Takenaka R, Miura K, Kanzaki H, Hori K, Kita M, Tsuzuki T, Kawano S, Kawahara Y, Yamamoto K

BACKGROUND/AIMS: The interaction between nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori remains controversial. We retrospectively investigated whether H. pylori infection exacerbates severe gastric mucosal injury among chronic NSAID users. METHODS: From...
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Prescription Pattern of NSAIDs and the Prevalence of NSAID-induced Gastrointestinal Risk Factors of Orthopaedic Patients in Clinical Practice in Korea

Lee SH, Han CD, Yang IH, Ha CW

This is a cross-sectional observational study undertaken to explore the current prescription pattern of non-steroidal anti-inflammatory drugs (NSAIDs) and the prevalence of NSAID-induced gastrointestinal (GI) risk factors of orthopaedic patients...
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The Influence of Non-steroidal Anti-inflammatory Drugs on Clinical Outcome in Patients with Bleeding Peptic Ulcers

Kim KH, Kim HY, Choi JW, Lee JY, Bae YD, Baek GH, Jang MK, Park JY, Lee JH, Yoo JY

  • KMID: 772860
  • Korean J Gastroenterol.
  • 2005 Nov;46(5):373-380.
BACKGROUND/AIMS: We conducted this study to find the clinical characteristics of ulcer bleeding that occurred in patients who had been taking non-steroidal anti-inflammatory drugs (NSAIDs) and to evaluate the...
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Preventive Efficacy and Safety of Rebamipide in Nonsteroidal Anti-Inflammatory Drug-Induced Mucosal Toxicity

Kim JH, Park SH, Cho CS, Lee ST, Yoo WH, Kim SK, Kang YM, Rew JS, Park YW, Lee SK, Lee YC, Park W, Lee DH

  • KMID: 1792359
  • Gut Liver.
  • 2014 Jul;8(4):371-379.
BACKGROUND/AIMS: The use of proton pump inhibitors or misoprostol is known to prevent the gastrointestinal complications of nonsteroidal anti-inflammatory drugs (NSAIDs). Rebamipide is known to increase the mucosal generation of...
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Mesalazine-induced Eosinophilic Pneumonia in a Patient with Crohn's Disease

Park JE, Hwangbo Y, Chang R, Chang YW, Jang JY, Kim BH, Dong SH, Kim HJ

  • KMID: 1062815
  • Korean J Gastroenterol.
  • 2009 Feb;53(2):116-120.
Mesalazine (5-aminosalicylic acid) and sulfasalazine are widely used in the treatment of inflammatory bowel disease. The pulmonary toxicity related to sulfasalazine was well-recognized complication and it was caused by sulfapyridine...
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Long-Term Outcomes of NSAID-Induced Small Intestinal Injury Assessed by Capsule Endoscopy in Korea: A Nationwide Multicenter Retrospective Study

Shim KN, Song EM, Jeen YT, Kim JO, Jeon SR, Chang DK, Song HJ, Lim YJ, Kim JS, Ye BD, Park CH, Jeon SW, Cheon JH, Lee KJ, Kim JH, Jang BI, Moon JS, Chun HJ, Choi MG, The Korean Gut Image Study Group

BACKGROUND/AIMS: We evaluated the long-term outcome and clinical course of patients of nonsteroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by performing capsule endoscopy (CE). METHODS: A multicenter retrospective study was conducted...
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Prevention of NSAID-Associated Gastroduodenal Injury in Healthy Volunteers-A Randomized, Double-Blind, Multicenter Study Comparing DA-9601 with Misoprostol

Lee KN, Lee OY, Choi MG, Choi SR, Lee DH, Lee YC, Kim TN, Choi SC, Rew JS, Seol SY

In addition to inhibiting cyclooxygenase and prostaglandin, nonsteroidal anti-inflammatory drugs (NSAIDs) may cause gastroduodenal injuries due to reactive oxygen species produced by recruited inflammatory cells. DA-9601 is a novel antioxidant...
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The IL-1B Genetic Polymorphism Is Associated with Aspirin-Induced Peptic Ulcers in a Korean Ethnic Group

Cho JH, Choi JS, Chun SW, Lee S, Han KJ, Kim HM

BACKGROUND/AIMS: Single nucleotide polymorphisms (SNPs) are associated with aspirin-induced peptic ulcers. However, SNPs of specific genes vary among races, and data regarding SNPs in the Korean population are scarce. In...
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A Case of Inferior Vena Cava Thrombosis and Acute Pancreatitis in a Patient with Ulcerative Colitis

Shin DH, Lee KH, Kim CH, Kim KH, Park SH, Chang DK, Lee JK, Lee KT

A 21-year-old man admitted complaining of sudden severe epigastric pain for 1 day. He had been diagnosed as ulcerative colitis (UC) and taking mesalazine for two months. UC was in...
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Lack of Association of Glutathione S-transferase P1 Ile105Val Polymorphism with Aspirin-Intolerant Asthma

Oh JM, Kim SH, Suh CH, Nahm DH, Park HS, Lee YM, Lee JH, Park CS, Shin HD

BACKGROUND: Glutathion S-transferase P1 (GSTP1), the abundant isoform of glutathione S-transferase in lung epithelium, plays an important role in cellular protection against oxidative stress and toxic foreign chemicals. GSTP1 (Ile105Val)...
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Importance of Age and Other Risk Factors in NSAID-induced Gastropathy

Lee HL, Han DS, Kim JB, Kim JP, Jeon YC, Sohn JH, Hahm JS

  • KMID: 772692
  • Korean J Gastroenterol.
  • 2004 Nov;44(5):246-251.
BACKGROUND/AIMS: It is clinically important to analyze the risk factors of NSAID-induced gastropathy because there could be no symptoms. Age is the most important risk factor according to previous...
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