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New Development of Anti-HIV Drugs

Kim JM

No abstract available.
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Application of HIV-1 Complementation System to Screen the Anti-AIDS Agents That Targets the Late Stage of HIV-1 Replication Cycle

Ryu JY, Choi SY, Kim YH, Park JS

  • KMID: 1561232
  • J Korean Soc Virol.
  • 2000 Sep;30(3):161-170.
No Abstract Available.
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Regional Experience of Abacavir: Valuable but Still has Unanswered Question

Bang JH

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Antiretroviral Therapy for Treatment of Human Immunodeficiency Virus Type 1 Infection

Oh MD

It has now been 20 years since the first demonstration that antiretroviral drug, azidothymidine, not only reduce human immunodeficiency virus type 1(HIV-1) replication but also improve clinical outcome. Antiretroviral therapy...
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Anesthetic Considerations for the HIV-Infected Pregnant Patient

Kuczkowski KM

It has been reported that women of childbearing age constitute a large percentage of the new cases of HIV/AIDS infection. Consequently, it is not uncommon to find pregnant women who...
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Characterization of Gp41 Polymorphisms in the Fusion Peptide Domain and T-20 (Enfuvirtide) Resistance-Associated Regions in Korean HIV-1 Isolates

Jang DH, Yoon CH, Choi BS, Chung YS, Kim HY, Chi SG, Kim SS

HIV-1 gp41 is an envelope protein that plays an essential role in virus entry. The mutation of gp41 affects HIV-1 entry and susceptibility to the fusion inhibitor T-20. Therefore, we...
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Structure-activity relationships of anti-HIV-1 peptides with disulfide linkage between D- and L-cysteine at positions i and i+3, respectively, derived from HIV-1 gp41 C-peptide

Lee MK, Kim HK, Lee TY, Hahm KS, Kim KL

  • KMID: 1105273
  • Exp Mol Med.
  • 2006 Feb;38(1):18-26.
The constrained alpha-helical structure of a C-peptide is useful for enhancing anti-HIV-1 activity. The i and i+3 positions in an alpha-helical structure are located close together, therefore D-Cys (dC) and...
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Diverse Effects of Small Molecule Inhibitors on Actin Cytoskeleton Dynamics in HIV-1 Infection

Shin Y, Choi BS, Kim KC, Kim K, Yoon CH

The dynamics of the actin cytoskeleton plays a pivotal role in the process of cell division, the transportation of organelles, vesicle trafficking and cell movement. Human immunodeficiency virus type 1...
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Intestinal Parasitosis in Relation to Anti-Retroviral Therapy, CD4+ T-cell Count and Diarrhea in HIV Patients

Khalil S, Mirdha BR, Sinha S, Panda A, Singh Y, Joseph A, Deb M

Intestinal parasitic infections are one of the major causes of diarrhea in human immunodeficiency virus (HIV) seropositive individuals. Antiretroviral therapy has markedly reduced the incidence of many opportunistic infections, but...
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Prevalence and Risk Factors of Low Bone Mineral Density in Korean HIV-Infected Patients: Impact of Abacavir and Zidovudine

Kim HS, Chin BS, Shin HS

Low bone mineral density (BMD) is common in HIV-infected patients. We aimed to describe the prevalence of low BMD and risk factors in Korean HIV-infected patients and to assess the...
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A Case of Lactic Acidosis Caused by Stavudine in an AIDS Patient

Cho BC, Han SH, Choi SH, Choi JY, Chang KH, Song YG, Kim JM

  • KMID: 759689
  • Korean J Intern Med.
  • 2004 Mar;19(1):66-69.
Nucleoside reverse transcriptase inhibitors (NRTIs), which are used for the treatment of human immunodeficiency virus (HIV) infection have been associated with a wide spectrum of clinical manifestations, including hepatic steatosis,...
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Disseminated Penicilliosis in a Korean Human Immunodeficiency Virus Infected Patient from Laos

Jung JY, Jo GH, Kim HS, Park MY, Shin JH, Chin BS, Bang JH, Shin HS

Penicillium marneffei may cause life-threatening systemic fungal infection in immune-compromised patients and it is endemic in Southeast Asia. A 39-yr-old HIV-infected male, living in Laos, presented with fever, cough, and...
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Five-Year Review of HIV-Hepatitis B Virus (HBV) Co-Infected Patients in a New York City AIDS Center

Kim JH, Psevdos G, Sharp V

A retrospective review of 4,721 human immunodeficiency virus (HIV)-infected patients, followed at St. Luke's Roosevelt Hospital Center, New York City, was conducted from January 1, 2005 to December 31, 2009....
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Factors Associated with HIV-1 Proviral DNA Loads in Patients with Undetectable Plasma RNA Load

Choi JY, Song YG, Kim YH, Kim CO, Kim MS, Chin BS, Han SH, Choi SH, Lee HS, Jeong SJ, Choi H, Kim JM

To evaluate factors associated with human immunodeficiency virus type 1 (HIV-1) proviral DNA load, we conducted a cross-sectional study of 36 chronically HIV-1- infected individuals with undetectable plasma viral RNA....
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The CD4 slope can be a predictor of immunologic recovery in advanced HIV patients: a case-control study

Kim KH, Yi J, Lee SH

BACKGROUND/AIMS: Advanced human immunodeficiency virus (HIV) infection, despite sustained viral suppression by highly active antiretroviral therapy (HAART), is a risk factor for poor immunologic recovery. However, some patients with advanced...
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HIV-Specific Cellular Immune Responses Are Stimulated by Structured Treatment Interruption in Chronically HIV-1 Infected Koreans

Choi JY, Song YG, Park YS, Yoon HJ, Kim MS, Kim YK, Shin SY, Kim JM

We evaluated the enhancing effect of structured treatment interruptions (STIs) on HIV-specific immunity in chronically HIV-1 infected Korean patients. A prospective case-control study was done with a total of 10...
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Change in Renal Function among HIV-Infected Koreans Receiving Tenofovir Disoproxil Fumarate-Backbone Antiretroviral Therapy: A 3-Year Follow-Up Study

Lee KH, Lee JU, Ku NS, Jeong SJ, Han SH, Choi JY, Song YG, Kim JM

PURPOSE: Tenofovir disoproxil fumarate (TDF) is commonly prescribed as a fixed-dose, co-formulated antiretroviral drug for HIV-1 infection. The major concern of long-term TDF use is renal dysfunction. However, little is...
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Predictors of Poor Retention in Care of HIV-infected Patients Receiving Antiretroviral Therapy in Korea: Five-Year Hospital-based Retrospective Cohort Study

Lee S, Lee SH, Lee SJ, Kim KH, Lee JE, Cho H, Lee SG, Chen DH, Chung JS, Kwak IS

Poor retention in care (RIC) is associated with higher antiretroviral therapy (ART) failure and worse survival. Identifying high risk patients for poor RIC is important for targeted intervention. A retrospective...
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Small Bowel Lymphoma Detected by MiroCam(R) Capsule Endoscope in a Patient with Acquired Immune Deficiency Syndrome

Baik SJ, Shim KN, Choi HJ, Jung SA, Yoo K

  • KMID: 783030
  • Korean J Gastroenterol.
  • 2008 Jul;52(1):37-41.
Human immunodeficiency virus (HIV) infection is a risk factor for developing non-Hodgkin's lymphoma. Most acquired immune deficiency syndrome (AIDS)-related lymphomas are high-grade B cell non-Hodgkin's lymphomas. The use of highly...
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Incidence of Atazanavir-associated Hyperbilirubinemia in Korean HIV Patients: 30 Months Follow-up Results in a Population with Low UDP-glucuronosyltransferase1A1*28 Allele Frequency

Choe PG, Park WB, Song JS, Kim NH, Song KH, Park SW, Kim HB, Kim NJ, Oh MD

Hyperbilirubinemia is frequently observed in Caucasian HIV patients treated with atazanavir. UDP-glucuronosyltransferase 1A1 polymorphism, UGT1A1*28, which is associated with atazanavir-induced hyperbilirubinemia, is less common in Asians than in Caucasians. However,...
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