- A Machine Learning Approach for Predicting In-Hospital Cardiac Arrest Using Single-Day Vital Signs, Laboratory Test Results, and International Classification of Disease-10 Block for Diagnosis
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Park H, Park CS
- KMID: 2565652
- Ann Lab Med.
- 2025 Mar;45(2):209-217.
- doi: 10.3343/alm.2024.0315
Background: Predicting in-hospital cardiac arrest (IHCA) is crucial for potentially reducing mortality and improving patient outcomes. However, most models, which rely solely on vital signs, may not comprehensively capture the... -
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- Clinical Pharmacogenetic Testing and Application: 2024 Updated Guidelines by the Korean Society for Laboratory Medicine
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Rim JH, Kim Yg, Kim S, Choi R, Lee JS, Park S, Lee W, Song EY, Lee SY, Chun S, on behalf of the Pharmacogenetics Guideline Task-Force Team of the Korean Society for Laboratory Medicine
- KMID: 2565644
- Ann Lab Med.
- 2025 Mar;45(2):121-132.
- doi: 10.3343/alm.2024.0572
In the era of precision medicine, pharmacogenetics has substantial potential for addressing inter-individual variability in drug responses. Although pharmacogenetics has been a research focus for many years, resulting in the... -
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- Prognostic Value of Residual Circulating Tumor DNA in Metastatic Pancreatic Ductal Adenocarcinoma
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Kim H, Lee J, Park MR, Choi Z, Han SJ, Kim D, Shin S, Lee ST, Choi JR, Park SW
- KMID: 2565651
- Ann Lab Med.
- 2025 Mar;45(2):199-208.
- doi: 10.3343/alm.2024.0345
Background: Circulating tumor DNA (ctDNA) is a potential biomarker in pancreatic ductal adenocarcinoma (PDAC). However, studies on residual ctDNA in patients post-chemotherapy are limited. We assessed the prognostic value of... -
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- Advancing Natural Killer Cell Therapy: Genetic Engineering Strategies for Enhanced Cancer Immunotherapy
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Park JD, Shin HE, An YS, Jang HJ, Park J, Kim SN, Park CG, Park W
- KMID: 2565646
- Ann Lab Med.
- 2025 Mar;45(2):146-159.
- doi: 10.3343/alm.2024.0380
Natural killer (NK) cells are pivotal innate immune system components that exhibit spontaneous cytolytic activity against abnormal cells, such as infected and tumor cells. NK cells have shown significant promise... -
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- Abnormalities in Chromosomes 5 and 7 in Myelodysplastic Syndrome and Acute Myeloid Leukemia
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Kendrick TS, Buic D, Fuller KA, Erber WN
- KMID: 2565645
- Ann Lab Med.
- 2025 Mar;45(2):133-145.
- doi: 10.3343/alm.2024.0477
Chromosomes 5 and 7 are large chromosomes that contain close to 1,000 genes each. Deletions of the long arms or loss of the entire chromosome (monosomy) are common defects in myeloid... -
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- Enhancing Clinical Cardiac Care: Predicting In-Hospital Cardiac Arrest With Machine Learning
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Kim S
- KMID: 2565643
- Ann Lab Med.
- 2025 Mar;45(2):117-120.
- doi: 10.3343/alm.2024.0696
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- CD69 Expression is Negatively Associated With T-Cell Immunity and Predicts Antiviral Therapy Response in Chronic Hepatitis B
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Gu Y, Bi Y, Huang Z, Liao C, Li X, Hu H, Xie H, Huang Y
- KMID: 2565650
- Ann Lab Med.
- 2025 Mar;45(2):185-198.
- doi: 10.3343/alm.2024.0178
Background: The function of CD69 expressed on T cells in chronic hepatitis B (CHB) remains unclear. We aimed to elucidate the roles of CD69 on T cells in the disease... -
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- Artificial Intelligence in Diagnostics: Enhancing Urine Test Accuracy Using a Mobile Phone–Based Reading System
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Kim HJ, Kim M, Zhang H, Kim HR, Jeon JW, Seo Y, Choi Q
- KMID: 2565649
- Ann Lab Med.
- 2025 Mar;45(2):178-184.
- doi: 10.3343/alm.2024.0304
Background: Urinalysis, an essential diagnostic tool, faces challenges in terms of standardization and accuracy. The use of artificial intelligence (AI) with mobile technology can potentially solve these challenges. Therefore, we... -
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- Reclassification of Acute Myeloid Leukemia According to the 2022 World Health Organization Classification and the International Consensus Classification Using Open-Source Data
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Yun J
- KMID: 2565648
- Ann Lab Med.
- 2025 Mar;45(2):170-177.
- doi: 10.3343/alm.2024.0194
Background: In 2022, the revised WHO classification and International Consensus Classification (ICC) for myeloid neoplasms were published. We examined the impact of these guidelines on AML diagnoses alongside the 2022... -
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- Performance Evaluation of the LabGenius C-CT/NG-BMX Assay for Chlamydia trachomatis and Neisseria gonorrhoeae Detection
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Lim YK, Kweon OJ, Park AJ, Kim H, Yoon S, Kim TH, Lee MK
- KMID: 2565653
- Ann Lab Med.
- 2025 Mar;45(2):218-222.
- doi: 10.3343/alm.2024.0118
The LabGenius C-CT/NG-BMX assay (LabGenius CT/NG; BIOMEDUX, Gyeonggi, Republic of Korea) is a recently developed real-time PCR assay that can simultaneously detect the sexually transmitted pathogens Chlamydia trachomatis (CT) and... -
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- TP53 Mutation Status in Myelodysplastic Neoplasm and Acute Myeloid Leukemia: Impact of Reclassification Based on the 5th WHO and International Consensus Classification Criteria: A Korean Multicenter Study
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Kim HY, Shin S, Lee JM, Kim IS, Kim B, Kim HJ, Choi YJ, Bae B, Kim Y, Ji E, Kim H, Kim H, Lee JS, Chang YH, Kim HK, Lee JY, Yu S, Kim M, Cho YU, Jang S, Kim M
- KMID: 2565647
- Ann Lab Med.
- 2025 Mar;45(2):160-169.
- doi: 10.3343/alm.2024.0351
Background: TP53 mutations are associated with poor prognosis in myelodysplastic neoplasm (MDS) and AML. The updated 5th WHO classification and International Consensus Classification (ICC) categorize TP53-mutated MDS and AML as... -
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- Clinical Outcomes and Molecular Characteristics of Bacteroides fragilis Infections
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Kim B, Kim M, Lee K, Lee Y
- KMID: 2565654
- Ann Lab Med.
- 2025 Mar;45(2):223-227.
- doi: 10.3343/alm.2024.0369
Bacteroides fragilis is the most common opportunistic anaerobic pathogen. In the absence of appropriate antimicrobial therapy, mortality rates associated with B. fragilis group infections can reach as high as 50%.... -
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