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Midtrimester maternal plasma concentrations of angiopoietin 1, angiopoietin 2, and placental growth factor in pregnant women who subsequently develop preeclampsia

Shim SS, Lee CH, Jun JK

OBJECTIVE: The aim of this study was to compare midtrimester maternal plasma concentrations of angiopoietin 1, angiopoietin 2, and placental growth factor between pregnant women who subsequently developed preeclampsia and...
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Expression of Angiopoietin-1 and Angiopoietin-2 mRNA in Eutopic and Ectopic Endometrium

Lee JY, An SS, Yun BI, Hur SE, Sohn IS, Kim SN

  • KMID: 2272371
  • Korean J Obstet Gynecol.
  • 2004 Jun;47(6):1171-1178.
OBJECTIVE: To investigate the mRNA expression of Angiopoietin (Ang)-1 and Ang-2 in ectopic and eutopic endometrium from women with or without endometriosis throughout the menstrual cycle. METHODS: Total RNA was extracted...
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The Study on the Expression of Angiopoietin-1, Angiopoietin-2, and Tie2 in Mouse Kidney Maturation

Kim W, Lee S, Sung MJ, Moon SO, Kim SK, Jang YB, Kim SS, Kang SK, Park SK

  • KMID: 2079395
  • Korean J Nephrol.
  • 2004 May;23(3):385-395.
BACKGROUND: The Angiopoietin-1 (Ang1), Angiopoietin-2 (Ang2) and Tie2 have essential role in angiogenesis in development. Ang1 and Ang2 are ligands which binds to their receptor, Tie2. METHODS: Expression of these...
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Angiopoietin-1 and Angiopoietin-2 Expression Imbalance Influence in Early Period After Subarachnoid Hemorrhage

Gu H, Fei ZH, Wang YQ, Yang JG, Zhao CH, Cai Y, Zhong XM

PURPOSE: Microvascular endothelial integrity is important for maintaining the blood-brain barrier (BBB). However, subarachnoid hemorrhage (SAH) disrupts this integrity, making the BBB dysfunctional—an important pathophysiological change after SAH. Angiopoietin-1 (Ang-1)...
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Angiopoietins in Diabetic Nephropathy

Lee EY, Gil HW, Yang JO, Koh JH, Chung CH, Hong SY

  • KMID: 2079686
  • Korean J Nephrol.
  • 2007 May;26(3):311-319.
PURPOSE: It has been reported that angiopoietins and Tie-2 receptor play an important role in the maintenance of glomerular filtration barrier in various glomerulonephritis models. We studied the role of...
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The expression of angiopoietin-1, angiopoietin-2, Tie-2 and vascular endothelial growth factor mRNA in normal ovary, benign ovarian cyst, and epithelial ovarian cancer

Jo YS, Moon HS, Chung HW, Kim SC, Chun SH

  • KMID: 2244586
  • Korean J Gynecol Oncol.
  • 2006 Jun;17(2):134-141.
OBJECTIVE: Vascular endothelial growth factor (VEGF) increases angiogenesis. It is known that one of angiogenetic factors, angiopoietin-1 (Ang-1) stabilizes maturity of normal vessels and angiopoietin-2 (Ang-2) antagonizes the action of...
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Maternal Plasma Angiopoietin-1 and Angiopoietin-2 in Pregnant Women with Chronic Hypertension

Kim E, Kang M, Jun JK

PURPOSE: The aim of this study was to investigate whether plasma angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) concentrations in pregnant women with chronic hypertension are different from those of normotensive pregnant...
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Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer

Hong S, Jung HI, Ahn TS, Kim HJ, Lee KT, Baek MJ, Bae SB

PURPOSE: Angiopoietin-1 (Ang-1) plays a crucial role in vascular and hematopoietic development, mainly through its cognate receptor, Tie-2. Increased levels of Ang-2 have been shown to be correlated with abnormal...
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The expression of Thymosin beta4 with angiogenic factors in epithelial ovarian cancer

Kim A, Chung HW, Kim JI, Chun SH, Moon HS

  • KMID: 2273346
  • Korean J Obstet Gynecol.
  • 2008 May;51(5):518-526.
OBJECTIVE: The aim of this study was to determine thymosin beta4 expression in epithelial ovarian cancer compared to normal ovarian tissue. METHODS: Normal and pathologic ovarian tissues were obtained from healthy...
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Expression of Angiopoietin 1, 2 and Their Common Receptor Tie2 in Human Gastric Carcinoma: Implication for Angiogenesis

Moon WS, Park HS, Yu KH, Jang KY, Kang MJ, Park H, Tarnawski

Angiogenesis, formation of new microvessels providing oxygen and nutrient supply, is essential for tumor growth. It is dependent on the production of angiogenic growth factors by tumor cells. Angiopoietin 1...
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Angiopoietin-1 and -2 and vascular endothelial growth factor expression in ovarian grafts after cryopreservation using two methods

Cho IA, Lee YJ, Lee HJ, Choi IY, Shin JK, Lee SA, Lee JH, Choi WJ

OBJECTIVE: The favored method of preserving fertility in young female cancer survivors is cryopreservation and autotransplantation of ovarian tissue. Reducing hypoxia until angiogenesis takes place is essential for the survival...
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Pathophysiological Role of Angiopoietin-2 in Human Coronary Atherosclerosis

Shin EK, Park MC, Lee JH, Kim DJ, Hahn JH, Park KH, Koh GY, Park JH

  • KMID: 1564364
  • Korean J Anat.
  • 2005 Aug;38(4):295-306.
Neovascularization is well known to occur in human atherosclerotic plaques; however, its pathophysiological roles, mechanism, and stimuli still remain unclear. Angiopoietin-1 and -2 belong to another vascular-specific growth factor family...
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Expression and Clinical Significance of Angiopoietin-2 and its Receptor Tie-2 in Invasive Breast Cancer

Park KS, Jung SH

PURPOSE: Breast carcinomas are highly malignant tumor that the angiogenesis factor, vascular endothelial growth factor and its receptors are overexpressed. To elucidate the role of Angiopoietin-2 (ANG2) and ANG2 receptor...
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Serum Vascular Endothelial Growth Factor and Angiopoietin-2 Are Associated with the Severity of Systemic Inflammation Rather than the Presence of Hemoptysis in Patients with Inflammatory Lung Disease

Park HY, Hahm CR, Jeon K, Koh WJ, Suh GY, Chung MP, Kim H, Kwon OJ, Um SW

PURPOSE: Vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2) are major mediators of angiogenesis and are induced by tissue inflammation and hypoxia. The purpose of this study was to investigate...
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Expression of angiogenic factors in cryopreserved mouse ovaries after heterotopic autotransplantation

Choi WJ, Seok JS, Choi IY, Park JK, Shin JK, Lee SA, Paik WY, Lee JH

OBJECTIVE: Revascularization is critical for successful ovarian tissue transplantation. Vascular endothelial growth factor (VEGF) and angiopoietin-2 (angpt-2) are the principal mediators of neovascularization. This study was designed to assess VEGF...
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Chronic Cerebral Hypoperfusion Induces Alterations of Matrix Metalloproteinase-9 and Angiopoietin-2 Levels in the Rat Hippocampus

Kim MS, Choi BR, Lee YW, Kim DH, Han YS, Jeon WK, Han JS

Angiogenic factors contribute to cerebral angiogenesis following cerebral hypoperfusion, and understanding these temporal changes is essential to developing effective treatments. The present study examined temporal alterations in angiogenesis-related matrix metalloproteinase-9...
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Influence of the vitrification solution on the angiogenic factors in vitrificated mouse ovarian tissue

Choi WJ, Lee JH, Park MH, Choi IY, Park JK, Shin JK, Lee SA, Paik WY, Lee JH

OBJECTIVE: To investigate the effect of the dimethyl sulfoxide (DMSO) and EFS-40 during vitrification on the expression of angiogenic factors in vitrified mouse ovarian tissue. METHODS: The ovarian tissues were obtained...
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Circulating Levels of Adipokines Predict the Occurrence of Acute Graft-versus-host Disease

Kim JS, You DB, Lim JY, Lee SE, Kim YJ, Kim HJ, Chung NG, Min CK

Currently, detecting biochemical differences before and after allogeneic stem cell transplantation (SCT) for improved prediction of acute graft-versus-host disease (aGVHD) is a major clinical challenge. In this pilot study, we...
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Relationship of Angiopoietin-2 Expression to Atherosclerosis in Middle Cerebral and Coronary Arteries

Shin EK, Park JW, Park MC, Kim CW, Ahn JS, Park KH, Kim DJ, Hahn JH, Koh GY, Park JH

  • KMID: 1510193
  • Korean J Anat.
  • 2006 Aug;39(4):269-278.
Atherosclerosis is a systemic and multifactorial disease, its incidence is raised recently. Cerebral and coronary atherosclerosis have some similar pathogenesis, but their relationship and mechanisms are still remain unclear. Intimal neovascularization in...
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Serial Plasma Levels of Angiogenic Factors in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Kim BH, Ko YG, Her AY, Kim JS, Hwang KC, Shin DH, Kim BK, Choi D, Ha JW, Hong MK, Jang Y

BACKGROUND AND OBJECTIVES: Patients with acute myocardial infarction show varying degrees of collateral development. However, the relationships between angiogenic factors and degree of collaterals are not well known. SUBJECTS AND METHODS:...
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