- Role of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the Growth Regulation of Anaplastic Thyroid Cancer Cells Lines
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Song JY, Kim TY, Kim WB, Shong YK, Rhee YS, Suck JH, Hong SJ
- KMID: 1511951
- J Korean Soc Endocrinol.
- 2006 Apr;21(2):125-131.
- doi: 10.3803/jkes.2008.21.2.125
BACKGROUND: Anaplastic thyroid carcinoma is one of the most aggressive human cancers with a median survival of only 6 months. Local surgical tumor debulking combined with radio-chemotherapy is generally used... -
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- Identification of the Fungal Pathogen that Causes Strawberry Anthracnose in Bangladesh and Evaluation of In Vitro Fungicide Activity
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Akhter MS, Alam S, Islam MS, Lee MW
- KMID: 2408775
- Mycobiology.
- 2009 Jun;37(2):77-81.
This study was conducted to identify the Colletotrichum species causing anthracnose disease of strawberry in Balgladesh and to evaluate in vitro activity of commercial fungicides it. Based on morphological and... -
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- The effect of 5-aminoimidazole-4-carboxamide-ribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells
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Kim WG, Choi HJ, Kim TY, Shong YK, Kim WB
- KMID: 2070111
- Korean J Intern Med.
- 2014 Jul;29(4):474-481.
BACKGROUND/AIMS: 5'-Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a cellular energy sensor that monitors intracellular AMP/adenosine triphosphate (ATP) ratios and is a key regulator of the proliferation and survival of... -
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- The Preconditioning with AICAR Protects Against Subsequent Renal Ischemia Reperfusion Injury
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Lee SJ, Chang YK, Na KR, Lee KW, Suh KS, Kim SY, Chang YS, Shin YT, Bang BK
- KMID: 1465956
- Korean J Nephrol.
- 2009 Mar;28(2):96-102.
PURPOSE:Preconditioning due to activation of AMPK might reduce ischemia-reperfusion (I/R) injury in the kidney, based on the key role of AMPK in preserving ATP. To evaluate this possibility, the effect... -
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- Cilostazol Decreases Ethanol-Mediated TNFalpha Expression in RAW264.7 Murine Macrophage and in Liver from Binge Drinking Mice
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Lee YJ, Eun JR
- KMID: 2071759
- Korean J Physiol Pharmacol.
- 2012 Apr;16(2):131-138.
- doi: 10.4196/kjpp.2012.16.2.131
Alcoholic hepatitis is a leading cause of liver failure in which the increased production of tumor necrosis factor alpha (TNFalpha) plays a critical role in progression of alcoholic liver disease.... -
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- Angiotensin II Modulates p130Cas of Podocytes by the Suppression of AMP-Activated Protein Kinase
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Ha TS, Park HY, Seong SB, Ahn HY
- KMID: 2363691
- J Korean Med Sci.
- 2016 Apr;31(4):535-541.
- doi: 10.3346/jkms.2016.31.4.535
Angiotensin II (Ang II) induces the pathological process of vascular structures, including renal glomeruli by hemodynamic and nonhemodynamic direct effects. In kidneys, Ang II plays an important role in the... -
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- The Effect of AMPK Activation on Wnt and sFRP5 in TNF-alpha Induced Adipocyte Metabolic Dysfunction in 3T3-L1 Cell
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Hong SW, Lee JM, Choi JH, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Kim SW, Lee WY
- KMID: 2270967
- Korean J Obes.
- 2012 Mar;21(1):29-36.
BACKGROUND: Chronic inflammation in adipose tissue is closely associated with metabolic diseases, such as, type 2 diabetes and obesity. In the present study, we investigated the Wnt signaling pathway and... -
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- Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha
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Qiang W, Weiqiang K, Qing Z, Pengju Z, Yi L
- KMID: 756077
- Exp Mol Med.
- 2007 Aug;39(4):535-543.
Insufficient intracellular fat oxidation is an important contributor to aging-related insulin resistance, while the precise mechanism underlying is unclear. AMP-activated protein kinase (AMPK) is an important regulator of intracellular fat... -
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- Chronic ethanol feeding impairs AMPK and MEF2 expression and is associated with GLUT4 decrease in rat myocardium
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Chen L, Wang F, Sun X, Zhou J, Gao L, Jiao Y, Hou X, Qin C, Zhao J
- KMID: 946653
- Exp Mol Med.
- 2010 Mar;42(3):205-215.
- doi: 10.3858/emm.2010.42.3.021
Chronic and heavy alcohol consumption is one of the causes of heart diseases. However, the effects of ethanol on insulin sensitivity in myocardium has been unclear. To investigate the effects... -
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