- Expression and functional characterization of amino acid transport system L in Saos2 human osteogenic sarcoma cells
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Kim SG, Kim HH, Kim CH, Kim DK
- KMID: 1567696
- J Korean Assoc Oral Maxillofac Surg.
- 2006 Jun;32(3):200-208.
inhibitor, 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid (BCH). The affinity of [14C]L-leucine uptake and the inhibition profiles of [14C]L-leucine uptake by various amino acids in the Saos2 cells were comparable with those for... -
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- Differential Expression of System L Amino Acid Transporters in Wound Healing Process of Rat Skin
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Jeong MJ, Kim CH, Choi BD, Jeong SJ, Park JC, Kim HJ, Park KJ, Kim DK
- KMID: 1512988
- Korean J Phys Anthropol.
- 2006 Mar;19(1):37-48.
The continuous growth and proliferation of cells are essential for the wound healing process, and the amino acid transporters plays an important role in the continuous growing and proliferating cells.... -
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- Functional characteristics of neutral amino acid transporter in opossum kidney (OK) cells
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Woo JS, Park MH, Oh SO, Jung JS, Kim YK, Lee SH
- KMID: 1554554
- Korean J Physiol Pharmacol.
- 1997 Apr;1(2):185-193.
The characteristics of Na+/-dependent cycloleucine uptake was investigated in OK cells with regard to substrate specificity and regulation by protein kinase C (PKC). Inhibition studies with different synthetic and natural amino acids showed... -
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- Expression of amino acid transport system L in the differentiation of periodontal ligament fibroblast cells
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Hwang KY, Kim DK, Kim CH, Jang HS, Park JC, Choi SM, Kim BO
- KMID: 2425005
- J Korean Acad Periodontol.
- 2006 Sep;36(3):783-796.
The periodontium is a topographically complex organ consisting of epithelial tissue, soft and mineralized tissues. Structures comprising the periodontium include the gingiva, periodontal ligament (PDL), cementum and the alveolar bone.... -
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- Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression
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Liang Z, Cho HT, Williams L, Zhu A, Liang K, Huang K, Wu H, Jiang C, Hong S, Crowe R, Goodman MM, Shim H
- KMID: 2313132
- Nucl Med Mol Imaging.
- 2011 Jun;45(2):93-102.
PURPOSE: L-type amino acid transporter 1 (LAT1) is essential for the transport of large neutral amino acids. However, its role in breast cancer growth remains largely unknown. The purpose of... -
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- JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells
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Choi DW, Kim DK, Kanai Y, Wempe MF, Endou H, Kim JK
- KMID: 2395254
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):599-607.
- doi: 10.4196/kjpp.2017.21.6.599
Most normal cells express L-type amino acid transporter 2 (LAT2). However, L-type amino acid transporter 1 (LAT1) is highly expressed in many tumor cells and presumed to support their increased... -
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- Role of gamma-aminobutyric acid B (GABA B) receptors in the regulation of kainic acid-induced cell death in mouse hippocampus
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Lee HK, Seo YJ, Choi SS, Kwon MS, Shim EJ, Lee JY, Suh HW
- KMID: 1116198
- Exp Mol Med.
- 2005 Dec;37(6):533-545.
Kainic acid (KA) is well-known as an excitatory, neurotoxic substance. In mice, KA administered intracerebroventricularly (i.c.v.) lead to morphological damage of hippocampus expecially concentrated on the CA3 pyramidal neurons. In... -
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