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Viral vectors for vaccine applications

Choi Y, Chang J

Traditional approach of inactivated or live-attenuated vaccine immunization has resulted in impressive success in the reduction and control of infectious disease outbreaks. However, many pathogens remain less amenable to deal...
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Recharacterization of Morphological and Genetic Feature of Getah Virus Isolated from South Korea

Lee SH, Yang DK, Kim HH, Jo HY, Choi SS, Park JW, Choi KS, Cho IS

Three QIAG93 strains, QIAG9301, QIAG9302 and QIAG9303 that have been identified as Getah virus (GETV) are analyzed in this study. The morphological features of three virus isolates were observed by...
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Recent vaccine technology in industrial animals

Kim H, Lee YK, Kang SC, Han BK, Choi KM

Various new technologies have been applied for developing vaccines against various animal diseases. Virus-like particle (VLP) vaccine technology was used for manufacturing the porcine circovirus type 2 and RNA particle...
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Development and Evaluation of Indirect ELISA for Detection of Antibodies to Getah Virus in Horse Serum

Lee SH, Yang DK, Kim HH, Jo HY, Choi SS, Cho IS

Getah virus (GETV) is a member of the genus Alphavirus in the family Togaviridae. GETV infection can occur in a wide range of vertebrate species, and the virus has been...
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Zoonotic encephalitides caused by arboviruses: transmission and epidemiology of alphaviruses and flaviviruses

Go YY, Balasuriya UBR, Lee CK

In this review, we mainly focus on zoonotic encephalitides caused by arthropod-borne viruses (arboviruses) of the families Flaviviridae (genus Flavivirus) and Togaviridae (genus Alphavirus) that are important in both humans...
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Expression and Purification of Recombinant Mayaro Virus Envelope Glycoproteins E1 and E2 to Develop a Mayaro Virus Detection System

Yi SY, Yoon K, Kwon J, Kim KE, Park K, Shin YB

Mayaro virus (MAYV) is a mosquito-transmitted alphavirus that produces an acute, usually non-fatal, febrile illness including Mayaro fever. Like other alphaviruses, the MAYV E1 and E2 envelope glycoproteins are major...
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Sero-surveillance of Getah Virus among Thoroughbred Horses in Korea

Jo HY, Yang DK, Kim HH, Choi SS, Kang KS, Yang SJ, Yang YJ, Cho IS

Getah virus (GETV), which is transmitted by mosquitoes, causes lower limb edema and stiffness in horses. In this study, we investigated the sero-surveillance of GETV among Thoroughbred racehorses in Korea...
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Establishment of reverse transcription polymerase chain reaction for detection of Getah virus infection in livestock

Lee SH, Yang DK, Kim HH, Choi SS, Cho IS

Getah virus (GETV) infection causes sporadic outbreaks of mild febrile illness in horses and reproductive failure in pigs. In this study, we established a reverse transcription polymerase chain reaction (RT-PCR)...
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Expression and Evaluation of Chikungunya Virus E1 and E2 Envelope Proteins for Serodiagnosis of Chikungunya Virus Infection

Cho B, Jeon BY, Kim J, Noh J, Kim J, Park M, Park S

PURPOSE: Chikungunya virus (CHIKV) causes endemic or epidemic outbreaks of CHIKV fever, which is a mosquitoe-transmitted viral disease in Africa, India, South-East Asia, and recently Southern Europe. Currently, serological diagnostic...
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