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IgE Sensitization Patterns to Commonly Consumed Foods Determined by Skin Prick Test in Korean Adults

Kim SR, Park HJ, Park KH, Lee JH, Park JW

Offending food allergens can vary with regional preferences in food consumption. In this study, we analysed sensitization rates to commonly consumed foods in Korean adults suspected of having food allergy....
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A comparison study on allergen components between Korean (Arachis fastigiata Shinpung) and American peanut (Arachis hypogaea Runner)

Park CW, Kim GI, Lee CH

The prevalence of peanut allergy in Korea is lower than in America. Peanut extract allergens between the two countries have not been standardized. This study was performed to compare the...
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Pharaoh Ant (Monomorium pharaonis): Newly Identified Important Inhalant Allergens in Bronchial Asthma

Kim CW, Kim DI, Choi SY, Park JW, Hong CS

The nonstinging house ant, Monomorium pharaonis (pharaoh ant), was recently identified as a cause of respiratory allergy. This study was performed to evaluate the extent of sensitization to pharaoh ant,...
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Major house dust mite allergen, Der p I, activates phospholipase D in human peripheral blood mononuclear cells from allergic patients: involvement of protein kinase C

Oh JW, Kim JH, Lee KS, Han JS

  • KMID: 1109304
  • Exp Mol Med.
  • 2000 Jun;32(2):67-71.
The major house-dust-mite allergen, Der p I, stimulates the phospholipase D (PLD) in peripheral blood mononuclear cells (PBMC) from allergic patients with maximal responses after 30 min exposure. At 30...
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Comparison of the ImmunoCAP Assay and AdvanSureâ„¢ AlloScreen Advanced Multiplex Specific IgE Detection Assay

Park KH, Lee J, Lee SC, Son YW, Sim DW, Lee JH, Park JW

PURPOSE: The AdvanSureâ„¢ AlloScreen assay is an advanced multiplex test that allows for simultaneous detection of specific IgE (sIgE) against multiple allergens. For precise identification of causative allergens in allergic...
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Relationship between Silent Gastroesophageal Reflux and Food Sensitization in Infants and Young Children with Recurrent Wheezing

Kang SK, Kim JK, Ahn SH, Oh JE, Kim JH, Lim DH, Son BK

It is known that early childhood wheezing associated with sensitization to allergens, including food, has an increased risk of developing asthma later during school age. Gastroesophageal reflux (GER) is well...
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Identification of Tyrophagus putrescentiae allergens and evaluation of cross-reactivity with Dermatophagoides pteronyssinus

Munhbayarlah S, Park JW, Ko SH, Ree HI, Hong CS

House dust mites are the most common cause of allergic sensitization in respiratory allergic patients in the world. Tyrophagus putrescentiae (TP), which was followed by Dermatophagoides farinae (DF) and Dermatophagoides...
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Identification of Chironomus kiiensis allergens, a dominant species of non-biting midges in Korea

Yong TS, Lee JS, Lee IY, Park SJ, Park GM, Ree HI, Park JW, Hong CS, Park HS

Non-biting midges are known to contain potent inhalant allergens. IgE antibody responses to the crude extract of Chironomus kiiensis adults, a dominant chironomid species in Korea, were examined. With the...
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Cytokine secretion patterns of T cells responding to haptenized-human serum albumin in toluene diisocyanate (TDI)-induced asthma patients

Lee M, Park S, Park HS, Youn JK

Our understanding immune response mechanisms to chemical allergens has been limited. It was partly due to the nature of antigens, recognized by T cells, not being well characterized. In...
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Effect of Interleukin-18 Gene Polymorphisms on Sensitization to Wheat Flour in Bakery Workers

Kim SH, Hur GY, Jin HJ, Choi H, Park HS

Lower respiratory symptoms in bakery workers may be induced by wheat flour and endotoxins. We hypothesized that endotoxins from wheat flour may stimulate innate immunity and that interleukin-18 (IL-18) gene...
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Isolation of rice allergenic cDNA clones from a rice cDNA library by immunoscreening with a polyclonal antibody specific to 16 kD rice allergenic protein

Kim NI, Kim WC, Lee SM, Lee HK, Rhee HI, Choi YS, Jung YH, Cha SH

  • KMID: 1029925
  • Exp Mol Med.
  • 1999 Dec;31(4):185-190.
Clinical cases of type-1 hypersensitive reaction to rice (Oryza sativa) have been reported in western countries as well as in Japan. Among rice proteins, 14-16 kD globulin proteins...
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Common Whelk (Buccinum undatum)Allergy:Identification of IgE-binding Components and Effects of Heating and Digestive Enzymes

Lee BJ, Park HS

In Korea, common whelk (Buccinum undatum) is a popular edible shellfish. The aim of this study was to observe the sensitization rate to common whelk and to characterize its allergens....
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Exhaled Nitric Oxide is Associated with Allergic Inflammation in Children

Choi BS, Kim KW, Lee YJ, Baek J, Park HB, Kim YH, Sohn MH, Kim KE

Exhaled nitric oxide (eNO) has been proposed as a noninvasive marker of airway inflammation in asthma. In asthmatic patients, exhaled NO levels have been shown to relate with other markers...
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Presence of specific IgG antibody to grain dust does not go with respiratory symptoms

Park HS, Suh CH, Nahm DH, Kim HY

A high prevalence of work-related symptoms in relation to grain dust exposure has been reported in grain dust workers, but the role of the specific IgG antibody is unknown. To...
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Quantitative measurement of serum allergen-specific IgE on protein chip

Kim TE, Park SW, Cho NY, Choi SY, Yong TS, Nahm BH, Lee S, Noh G

  • KMID: 1081465
  • Exp Mol Med.
  • 2002 May;34(2):152-158.
Type I allergy is an immunoglobulin E (IgE)-mediated hypersensitivity disease inflicting more than quarter of the world population. In order to identify allergen sources, skin provocation test and IgE serology...
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IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model

Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK

IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream...
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Dermatophagoides Farinae, an Important Allergenic Substance in Buckwheat-Husk Pillows

Hong CS, Park HS, Oh SH

Inhalation of buckwheat flour as well as ingestion of buckwheat foods induces bronchial asthma. The buckwheat flour attached to the husks used as bed pillow filling can provoke bronchial asthma...
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Blockade of airway inflammation and hyper-responsiveness by an angiopoietin-1 variant, COMP-Ang1

Lee KS, Lee KY, Kim SR, Park HS, Park SJ, Min KH, Cho CH, Koh GY, Park HS, Lee YC

  • KMID: 1091068
  • Exp Mol Med.
  • 2007 Dec;39(6):733-745.
Inflammation of the asthmatic airway is usually accompanied by increased vascular permeability and plasma exudation. Angiopoietin-1 (Ang1) has potential therapeutic applications in preventing vascular leakage. Recently, we developed a soluble,...
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