- Activities of Hepatic Enzymes for Ethanol Metabolism in Cholestatic Rats with Acute Ethanol Intoxication
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Mun KC, Kwak CS, Jo YH
- KMID: 2304643
- Korean J Gastroenterol.
- 1999 Jul;34(1):50-55.
No abstract available. -
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- Analysis of Breath Alcohol Degradation and Alcohol Metabolic Enzymes in a Korean Male Population
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Lee SD, Lee YS, Yoo SH
- KMID: 2082729
- Korean J Leg Med.
- 2009 May;33(1):60-64.
To evaluate the concentration-time profiles of breath ethanol in degradation phase in proportion to the amount of alcohol, we carried out the controlled drinking study for 24 healthy males. Studies... -
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- Alcohol dehydrogenase activity in nonalcoholics without liver disease and alcoholic liver disease
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Tak WY, Kwen JG, Lee CH, Youn YM, An BC, Kwak KS, Choi YH, Chung JM, Yun YK, Kwak CS
- KMID: 1698229
- Korean J Intern Med.
- 1992 Nov;43(5):604-612.
No abstract available. -
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- Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes
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Kim YH, Shin MJ
- KMID: 1081461
- Exp Mol Med.
- 2002 May;34(2):123-130.
Membrane-associated cytotoxicity induced by hydrophobic bile salts is a major contributing factor leading to liver diseases. Administration of ursodeoxycholate reduces serum liver enzymes in chronic liver diseases but the nature... -
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- Effects of Aging on the Gastric and Hepatic Alcohol Dehydrogenase Activities in Rats
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Ryu JH, Kang JS, Lee CH, Jeon YC, Choi HS
- KMID: 1772567
- Korean J Gastroenterol.
- 1999 Dec;34(6):756-763.
BACKGROUND/AIMS: Relationship between gastric alcohol dehydrogenase (GADH) activity and first- pass metabolism of alcohol and the age-dependent changes in hepatic alcohol metabolism are reported. This study was performed in order... -
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- The Extract of Limonium tetragonum Protected Liver against Acute Alcohol Toxicity by Enhancing Ethanol Metabolism and Antioxidant Enzyme Activities
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Kim NH, Sung SH, Heo JD, Jeong EJ
- KMID: 2409600
- Nat Prod Sci.
- 2015 Mar;21(1):54-58.
- doi: 10.0000/nps.2015.21.1.54
The protective effect of EtOAc fraction of Limonium tetragonum extract (EALT) against alcoholinduced hepatotoxicity was assessed following acute ethanol intoxication in Spraque-Dawley rats. EALT (200 mg/kg p.o.) was administrated once... -
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- Effect of thyroid hormone on the alcohol dehydrogenase activities in rat tissues
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Kim DS, Lee CB, Park YS, Ahn YH, Kim TW, Kee CS, Kang JS, Om AS
- KMID: 1129903
- J Korean Med Sci.
- 2001 Jun;16(3):313-316.
- doi: 10.3346/jkms.2001.16.3.313
The effects of thyroid hormone on hepatic and gastric alcohol dehydrogenase (ADH) activities (nM of NADH/min/mg of cytosolic protein) have been investigated in male Sprague Dawley rats treated with thyroxine... -
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- Effect of the Mixture of Pueraria lobata and Sorbus commixta Extract on the Alcohol-induced Hangover in Rats
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Hong SC, Yoo JH, Oh MH, Lee H, Park YS, Parthasarathi S, Park JD, Pyo MK
- KMID: 2312880
- Nat Prod Sci.
- 2015 Jun;21(2):98-103.
- doi: 10.0000/nps.2015.21.2.98
Pueraiae Radix (PR), Pueratia Folium (PF) and Sorbus commixta (SC) mixture, namely GS-SP (PR (1)/PF (2)/SC (0.5): v/v/v) was developed as hangover-relieving elixir and its effects on alcoholic metabolism have... -
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- A Case of Sjogren-Larsson Syndrome
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Lee KJ, Kim JB, Lee DH, Shin SM, Lee SJ
- KMID: 1879519
- J Korean Pediatr Soc.
- 1994 Dec;37(12):1757-1761.
Sjogren-Larsson Syndrome is a rare disorder chracterized by congenital icthyosis, spastic diplegia or tetraplegia and mental retardation. The inheritance is autosomal recessive, due to deficiency of alcohol dehydrogenase activity of... -
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- Two Cases of Ethylene Glycol Poisoning
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Kim JJ, Yun SH, Jung HM, Kim JH, Han SB, Kim JS, Paik JH
- KMID: 1482717
- J Korean Soc Clin Toxicol.
- 2013 Jun;11(1):36-40.
Ethylene glycol poisoning is treated mainly by alcohol dehydrogenase inhibition therapy and hemodialysis. Early recognition and initiation of treatment is important because toxic metabolites increase over time by hepatic metabolism;... -
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- Effects of Chongkukjang Intake on Lipid Metabolism and Liver Function in Ethanol Consumed Rats
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Lee EH, Chyun JH
- KMID: 2260667
- Korean J Nutr.
- 2007 Dec;40(8):684-692.
This study was performed to investigate the effect of chongkukjang intake on lipid metabolism and liver function in ethanol consumed rats. Twenty one Sprague-Dawley male rats aging 4 weeks old... -
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- The Effect of ADH1B and NQO2 Polymorphisms on the Age of Onset of Alcohol Dependence and Alcohol Withdrawal Symptoms
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Lee YS, Han DH, Yoon SG, Choi SW, Joe KH, Seo JS
- KMID: 2341307
- J Korean Neuropsychiatr Assoc.
- 2007 May;46(3):237-244.
OBJECTIVES: We hypothesized that polymorphisms of ADH1B and NQO2 could have an effect on the onset of alcohol dependence and withdrawal symptoms. METHODS: PCR (polymerase chain reaction) and RFLP (restriction fragment... -
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- Association Between Polymorphisms of Ethanol-Metabolizing Enzymes and Susceptibility to Alcoholic Cirrhosis in a Korean Male Population
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Lee HC, Lee HS, Jung SH, Yi SY, Jung HK, Yoon JH, Kim CY
- KMID: 648356
- J Korean Med Sci.
- 2001 Dec;16(6):745-750.
- doi: 10.3346/jkms.2001.16.6.745
Alcohol is oxidized to acetaldehyde by alcohol dehydrogenase (ADH) and cytochrome P-4502E1 (CYP2E1), and then to acetate by aldehyde dehydrogenase (ALDH). Polymorphisms of these ethanol-metabolizing enzymes may be associated with... -
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- The Enzymatic Approach of Zygomycosis - Causing Mucorales
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Ko HS, Taguchi H, Takizawa K, Fukusima K, Kim HS
- KMID: 1513576
- Korean J Med Mycol.
- 2007 Mar;12(1):9-17.
Various oxidases and hydrolytic enzymes were analyzed to investigate the relationship between these enzymes and the skin pathogenicity of 18 Mucorales strains. Each strain was cultured in a nutrient medium... -
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- A Case of Ethylene Glycol intoxication with Acute Renal Injury: Successful Recovery by Fomepizole and Renal Replacement Therapy
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Song CH, Bae HJ, Ham YR, Na KR, Lee KW, Choi DE
- KMID: 2401153
- Electrolyte Blood Press.
- 2017 Dec;15(2):47-51.
- doi: 10.5049/EBP.2017.15.2.47
Ethylene glycol is a widely used and readily available substance. Ethylene glycol ingestion does not cause direct toxicity; however, its metabolites are highly toxic and can be fatal even in... -
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- Clinical Review of Toxic Alcohol Poisoning Cases in Korea
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Rhee NG, Chung SP, Park IC, Lee KR, Kim HJ, Kim GB, Cho YS, Kwon IH, Kim SW
- KMID: 1437675
- J Korean Soc Clin Toxicol.
- 2012 Jun;10(1):15-21.
PURPOSE: Toxic alcohols are responsible for accidental and suicide motivated poisonings, resulting in death or permanent sequelae for the afflicted patients. Major therapeutic modalities in these cases include treatment with... -
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- Effect of ethanol on Na+-Pi uptake in opossum kidney cells: Role of membrane fluidization and reactive oxygen species
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Park IH, Hwang MY, Woo JS, Jung JS, Kim YK
- KMID: 2071555
- Korean J Physiol Pharmacol.
- 1999 Oct;3(5):529-538.
This study was undertaken to examine the effect of ethanol on Na+-dependent phosphate (Na+-Pi) uptake in opossum kidney (OK) cells, an established renal proximal tubular cell line. Ethanol inhibited Na+-dependent component of phosphate... -
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- Effects of Genetic Polymorphisms of Ethanol-Metabolizing Enzymes on Alcohol Drinking Behaviors
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Kee JY, Kim MO, You IY, Chai JY, Hong ES, An SC, Kim H, Park SM, Youn SJ, Chae HB
- KMID: 863142
- Korean J Hepatol.
- 2003 Jun;9(2):89-97.
BACKGROUND/AIMS: Genetic variations of ethanol-metabolizing enzymes can affect alcohol drinking behavior. The aims of this study were to investigate and compare the distributions of these genetic polymorphisms between a... -
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- Uncoventional Views on Certain Aspects of Toxin-Induced Metabolic Acidosis
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Oh MS
- KMID: 1463000
- Electrolyte Blood Press.
- 2010 Jun;8(1):32-37.
- doi: 10.5049/EBP.2010.8.1.32
This discussion will highlight the following 9 specific points that related to metabolic acidosis caused by various toxins. The current recommendation suggests that alcohol dehydrogenase inhibitor fomepizole is preferred to... -
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- Mitochondrial Dysfunction and Apoptosis Related Gene Expression in A beta(25-35)-Treated Human Neuroblastoma Cell Line, SK-N-SH
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Choi YS, Kim SH
- KMID: 2338986
- J Korean Geriatr Soc.
- 2009 Sep;13(3):142-151.
BACKGROUND: Mitochondrial dysfunction plays an important role in Abeta-induced neuronal toxicity in Alzheimer's disease (AD). We measured the membrane potentials of mitochondria (delta psim) and assessed the genetic expressions of... -
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