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Optimal Hypoxic Preconditioning of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells (hES-MSCs) and Their Characteristics

Lee SM, Jun DW, Kang HT, Oh JH, Saeed WK, Ahn SB

Background and Objectives: Hypoxia is frequently used to enhance stem cell function. However, the optimal level of hypoxia for growth and function of human embryonic stem cell-derived mesenchymal stem cells...
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Effects of vitamin D supplements in patients with chronic hepatitis C: a randomized, multi-center, open label study

Jeong JY, Jun DW, Park SJ, Sohn JH, Kim SG, Lee SW, Jeong SW, Kim MY, Kim W, Shim JJ, Kim HS, Suk KT, Ahn SB

Background/Aims: We aimed to assess the role of vitamin D supplementation in the response to pegylated interferon-α (PEG-IFN-α) plus ribavirin (RBV) treatment in patients with chronic hepatitis C (CHC). Methods: Our...
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Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease

Ahn SB, Jun DW, Jang K, Lee BH, Shin KJ

BACKGROUND/AIMS: Intestinal cholesterol absorption includes intestinal Niemann-Pick C1-like 1 (NPC1L1) and is an important target pathway in nonalcoholic fatty liver disease (NAFLD). We investigated the expression of NPC1L1 and its...
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A Case of Achieving Partial Remission with Sequential Treatment of Transarterial Chemoemoblization after Transarterial Radioembolization in Old Patient with Hepatocellular Carcinoma with Multiple Metastasis

Hwang SY, Lee SM, Im JW, Jeon KJ, Ahn SB, Park JY

The number of older adults with hepatocelluar carcinoma (HCC) has been increasing with longer life expectancy and earlier diagnosis and treatment. However, older patients have lesser function reserve of multiple...
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Validation of a Paper and Pencil Test Battery for the Diagnosis of Minimal Hepatic Encephalopathy in Korea

Jeong JY, Jun DW, Bai D, Kim JY, Sohn JH, Ahn SB, Kim SG, Kim TY, Kim HS, Jeong SW, Cho YK, Song DS, Kim HY, Jung YK, Yoon EL

The aim of this study was to validate a new paper and pencil test battery to diagnose minimal hepatic encephalopathy (MHE) in Korea. A new paper and pencil test battery...
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A Case of Achieving Complete Remission with Combination of Sorafenib and Tegafur in Patients with Hepatocellular Carcinoma with Progression of Disease after Sorafenib Therapy

Hwang SY, Lee SM, Im JW, Jeon KJ, Ahn SB, Park JY, Choi CW, Yang KM

Sorafenib is the only approved targeted agent as the first line systemic therapy for treatment of advanced hepatocellular carcinoma (HCC). However, the improvement of survival duration under 3 months is...
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A Case of Achieving Complete Remission with Stereotactic Body Radiation Therapy in Patients with Hepatocellular Carcinoma with Macrovascular Invasion after Repeated Transarerial Chemoembolization

Hwang SY, Lee SM, Im JW, Jeon KJ, Ahn SB, Ji EK, Park JY, Choi CW, Yang GM

Transarterial chemoembolization (TACE) is the worldwide procedure performed for patients with various stage hepatoceullar carcinoma (HCC), but is not yet considered as curative treatment because of relatively high local recurrence...
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Locoregional Treatment of Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis

Hwang SY, Kim RG, Choi CW, Ahn SB

Hepatocellular carcinoma (HCC) patients with portal vein tumor thrombosis (PVTT) have a extremely poor prognosis. According to the Barcelona Clinic Liver Cancer guideline, sorafenib is a standard therapy in this...
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A Proton Pump Inhibitor's Effect on Bone Metabolism Mediated by Osteoclast Action in Old Age: A Prospective Randomized Study

Jo Y, Park E, Ahn SB, Jo YK, Son B, Kim SH, Park YS, Kim HJ

BACKGROUND/AIMS: Proton pump inhibitors (PPIs) act by irreversibly binding to the H+-K+-ATPase of the proton pump in parietal cells and may possibly affect the vacuolar H+-ATPase in osteoclasts. METHODS: We investigated...
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Increased Risk of Asymptomatic Gallstones in Patients With Ulcerative Colitis

Ha JH, Park YS, Seon CS, Son BK, Ahn SB, Jo YK, Kim SH, Jo YJ, Kim JH, Han JH, Jung YY, Chung SH

BACKGROUND/AIMS: The relationship between Crohn's disease and gallstones is established. However, the prevalence and risk factors for gallstones in patients with ulcerative colitis (UC) are not yet well understood. The...
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A Case of Achieving Complete Remission with Combination of Stereotac-tic Body Radiation Therapy and Transarterial Chemoemoblization in Pa-tients with 4.8 cm Sized Infiltrative Hepatocellular Carcinoma with Arte-riovenous Shunt

Hwang SY, Lee SM, Im JW, Kim JS, Jeon KJ, Ahn SB, Ji EK, Kang HC, Choi CW, Yang GM

Infiltrative hepatocellular carcinoma (HCC) patients have a poor prognosis because most patients present with advanced disease. Although tumor size is small, ablation therapy is difficult because it is difficult to...
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Osler-Weber-Rendu Disease Presenting as Recurrent Portosystemic Encephalopathy in a 75-year-old Female Patient

Ha J, Son BK, Ahn SB, Jo YK, Kim SH, Jo YJ, Park YS, Jung YY

Osler-Weber-Rendu disease is a rare autosomal dominant disorder of fibrovascular tissues, characterized by a classic triad of mucocutaneous telangiectasias, recurrent hemorrhages, and a familial occurrence. Portosystemic encephalopathy in a patient...
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Alcohol Drinking Increased the Risk of Advanced Colorectal Adenomas

Song YK, Park YS, Seon CS, Lim HJ, Son BK, Ahn SB, Jo YK, Kim SH, Jo YJ, Lee JH, Kim SC

BACKGROUND/AIMS: Age, sex, gene and life style are modulating risks for colon cancer. Although alcohol intake may impact on colorectal adenoma, clear association has not been established yet. We aimed...
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A Case Report of Primary Duodenal Tuberculosis Mimicking a Malignant Tumor

Jung JH, Kim SH, Kim MJ, Cho YK, Ahn SB, Son BK, Jo YJ, Park YS

Tuberculosis remains a serious infectious disease with primary features of pulmonary manifestation in Korea. However, duodenal tuberculosis is rare in gastrointestinal cases of extrapulmonary tuberculosis. Here, we report a case...
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Characteristics and immuno-modulatory effects of Enterococcus faecium JS1-8 isolated from Kimchi

Ahn SB, Park HE, Lee SM, Kim SY, Lee WK

Characteristics and immuno-modulatory effects of Enterococcus (E.) faecium JS1-8 isolated from Kimchi were investigated for potential probiotic use. We measured their acid, bile, and heat tolerances, adhesion properties in Caco-2...
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Spontaneous Arterial Bleeding in Patients with Alcoholic Liver Cirrhosis: a Series of Three Cases

Seon CS, Jo Y, Lee J, Jo YK, Ahn SB, Son B, Cho YK

Spontaneous arterial bleeding has been reported rarely. In a patient consuming heavy amounts of alcohol with alcoholic liver cirrhosis, spontaneous bleeding can be evoked by thrombocytopenia, altered platelet function, and...
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Refractory Duodenal Crohn's Disease Successfully Treated with Infliximab

Kim YL, Park YS, Park EK, Park DR, Choi GS, Ahn SB, Kim SH, Jo YJ

Crohn's disease (CD) may involve any part of the gastrointestinal tract, from the mouth to the anus. Approximately >90% of cases occur in the small bowel and colon. Upper gastrointestinal...
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Characteristics and immuno-modulatory effects of Weissella cibaria JW15 isolated from Kimchi, Korea traditional fermented food, for probiotic use

Ahn SB, Park HE, Lee SM, Kim SY, Shon MY, Lee WK

  • KMID: 1703513
  • J Biomed Res.
  • 2013 Dec;14(4):206-211.
In this study, characteristics and immuno-modulatory effects of Weissella cibaria JW15 isolated from Kimchi, traditional Korean fermented food, were examined for investigation of the capacity of potentially probiotic strains. We...
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Gastric Outlet Obstruction Due to Gastric Amyloidosis Mimicking Malignancy in a Patient with Ankylosing Spondylitis

Seon CS, Park YS, Jung YM, Choi JH, Son BK, Ahn SB, Kim SH, Jo YJ

  • KMID: 2165427
  • Clin Endosc.
  • 2013 Nov;46(6):651-655.
Amyloidosis is a group of disorders characterized by the extracellular accumulation of insoluble, fibrillar proteins in various organs and tissues. It is classified, on the basis of the identity of...
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A Case of Crohn's Disease Having Normal Delivery after Infliximab Treatment during Early Pregnancy

Jang YW, Park YS, Kim SH, Jo YJ, Jo YK, Ahn SB, Seo YS, Hong YO

Infliximab is a chimeric IgG1 monoclonal antibody to tumor necrosis factor (TNF)-alpha used in the treatment of steroid refractory or dependent Crohn's disease (CD). Patients with active CD are more...
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