Clin Endosc.  2014 Jul;47(4):346-349. 10.5946/ce.2014.47.4.346.

A Case Report of Primary Duodenal Tuberculosis Mimicking a Malignant Tumor

Affiliations
  • 1Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea. shkim@eulji.ac.kr

Abstract

Tuberculosis remains a serious infectious disease with primary features of pulmonary manifestation in Korea. However, duodenal tuberculosis is rare in gastrointestinal cases of extrapulmonary tuberculosis. Here, we report a case of primary duodenal tuberculosis mistaken as a malignant tumor and diagnosed with QuantiFERON-TB GOLD (Cellestis Ltd.) in an immunocompetent male patient.

Keyword

Primary duodenal tuberculosis; 18F-FDG PET/CT; QuantiFERON-TB GOLD

MeSH Terms

Communicable Diseases
Humans
Korea
Male
Tuberculosis*

Figure

  • Fig. 1 Initial gastroduodenoscopy. An ulcerohypertrophic mass is noted at the duodenal second portion below the ampulla of Vater.

  • Fig. 2 Abdomen computed tomography. (A, B) The initial scan shows an ulcerohypertrophic lesion in the duodenal second to third portion (black arrow) and mass-like, multiple perilesional enlarged lymph nodes with some necrotic changes (white arrow). (C, D) After antituberculosis treatment for 6 months, the duodenal lesion (black arrow) and multiple lymph nodes (white arrow) were decreased.

  • Fig. 3 Histopathological examination shows granulomatous inflammation with necrosis (H&E stain, ×400).

  • Fig. 4 Transparent capped endoscopy shows a scared lesion with central depression and peripheral reepithelization at 1 month after treatment.


Reference

1. Kim HJ. Current status of tuberculosis in Korea. Korean J Med. 2012; 82:257–262.
Article
2. Lamberty G, Pappalardo E, Dresse D, Denoël A. Primary duodenal tuberculosis: a case report. Acta Chir Belg. 2008; 108:590–591. PMID: 19051473.
Article
3. Sharma MP, Bhatia V. Abdominal tuberculosis. Indian J Med Res. 2004; 120:305–315. PMID: 15520484.
4. Khuroo MS, Khuroo NS. Abdominal tuberculosis. In : Madkour MM, editor. Tuberculosis. Berlin: Springer;2004. p. 659–678.
5. Rao YG, Pande GK, Sahni P, Chattopadhyay TK. Gastroduodenal tuberculosis management guidelines, based on a large experience and a review of the literature. Can J Surg. 2004; 47:364–368. PMID: 15540690.
6. Lazarus AA, Thilagar B. Abdominal tuberculosis. Dis Mon. 2007; 53:32–38. PMID: 17224321.
Article
7. Rosenbaum SJ, Lind T, Antoch G, Bockisch A. False-positive FDG PET uptake: the role of PET/CT. Eur Radiol. 2006; 16:1054–1065. PMID: 16365730.
8. Tian G, Xiao Y, Chen B, Guan H, Deng QY. Multi-site abdominal tuberculosis mimics malignancy on 18F-FDG PET/CT: report of three cases. World J Gastroenterol. 2010; 16:4237–4242. PMID: 20806445.
9. Kim YS, Kim YH, Lee KM, Kim JS, Park YS. IBD Study Group of the Korean Association of the Study of Intestinal Diseases. Diagnostic guideline of intestinal tuberculosis. Korean J Gastroenterol. 2009; 53:177–186. PMID: 19835219.
10. Yönal O, Hamzaoğlu HO. What is the most accurate method for the diagnosis of intestinal tuberculosis? Turk J Gastroenterol. 2010; 21:91–96. PMID: 20549889.
Article
11. Nishimura T, Hasegawa N, Mori M, et al. Accuracy of an interferon-gamma release assay to detect active pulmonary and extra-pulmonary tuberculosis. Int J Tuberc Lung Dis. 2008; 12:269–274. PMID: 18284831.
12. Lee HM, Cho SG, Kang HK, et al. The usefulness of whole-blood interferon-gamma release assay for the diagnosis of extra-pulmonary tuberculosis. Tuberc Respir Dis. 2009; 67:331–337.
Article
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