Gut Liver.  2009 Jun;3(2):130-133. 10.5009/gnl.2009.3.2.130.

Pseudoinvasion in an Adenomatous Polyp of the Colon Mimicking Invasive Colon Cancer

Affiliations
  • 1Department of Gastroenterology, Hanyang University College of Medicine, Guri Hospital, Guri, Korea. hands@hanyang.ac.kr
  • 2Department of Pathology, Hanyang University College of Medicine, Guri Hospital, Guri, Korea.

Abstract

Pseudoinvasion or pseudocarcinomatous invasion in an adenomatous polyp of the colon can be unfamiliar to an endoscopist. Pseudoinvasion in an adenomatous polyp represents prolapse of the adenomatous epithelium into its stalk. In most cases its morphology does not differ from of general adenomatous polyps, but in some cases it can morphologically mimic a malignant polyp with submucosal invasion due to mass- like lesioning of its stalk. This makes it difficult for endoscopists to differentiate pseudoinvasion in an adenoma from an invasive carcinoma by conventional endoscopy; instead, endoscopic ultrasonography can provide useful information for differentiating these conditions. We report on an 82-year-old man who presented with a large pedunculated polyp with a thick stalk in the sigmoid colon, which mimicked a submucosal invasive carcinoma. The patient was diagnosed with pseudoinvasion in an adenomatous polyp after segmental resection of the sigmoid colon.

Keyword

Pseudoinvasion; Adenomatous polyps; Malignant polyp; EUS

MeSH Terms

Adenoma
Adenomatous Polyps
Aged, 80 and over
Colon
Colon, Sigmoid
Colonic Neoplasms
Endosonography
Epithelium
Humans
Hydrazines
Polyps
Prolapse
Hydrazines
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