- Enhanced Expression of Aldosterone Synthase and Adrenomedullin in Left and Right Ventricular Hypertrophy in Rats
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Lee JU, Lee S, Kim S, Lee WJ
- KMID: 1615003
- Korean J Physiol Pharmacol.
- 2002 Apr;6(2):121-126.
The pathophysiological implications of aldosterone and adrenomedullin in the cardiac ventricular hypertrophy were examined. Male Sprague-Dawley rats were treated with deoxycorticosterone acetate (DOCA)-salt and monocrotaline (MCT) to selectively elicit left... -
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- Adrenomedullin and The Kidney
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Kim W
- KMID: 2134793
- Electrolyte Blood Press.
- 2005 Mar;3(1):24-31.
Adrenomedullin (AM) is a multi-functional peptide discovered in human pheochromocytoma. Initially, it was suggested that AM was synthesized only by tumor cells, however, subsequent studies revealed that it was produced... -
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- Effect of Adrenomedullin on Proliferation and Mitogen-Activated Protein Kinase Activity in Osteosarcoma Cell Lines (MG63, U2OS)
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Kim JR, Choi BW, Park JH, Kim KH
- KMID: 2336175
- J Korean Orthop Assoc.
- 2008 Dec;43(6):775-782.
PURPOSE: The aims investigated how how human osteosarcoma cell proliferation and the MAP kinases cascade are regulated, in the MG63 and U2OS human osteosarcoma cell lines after stimulating them with... -
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- The Anti-apoptotic Effect of Adrenomedullin on Vascular Endothelial Cells in Radiocontrast Media-induced Apoptosis
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Kang KP, Lee AS, Jung YJ, Kim DH, Ko KS, Choi KH, Jeong YW, Lee S, Park SK, Sung MJ, Kim W
- KMID: 2253610
- Korean J Nephrol.
- 2008 Jan;27(1):4-12.
PURPOSE: Because vascular endothelial cells play a pivotal role in the vascular diseases, damage of vascular endothelial cells lead to progression of vascular disease. Apoptotic damage of cells is an... -
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- Bio-Molecular Markers for Cardiovascular Disease: Significance of Natriuretic Peptides and Adrenomedullin
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Horio T, Kawano Y
- KMID: 2225714
- Korean Circ J.
- 2008 Oct;38(10):507-513.
- doi: 10.4070/kcj.2008.38.10.507
There are many established and proposed bio-molecular markers for cardiovascular disease, including vasoactive substances, substances related to inflammation and oxidative stress, and substances involved in tissue structure and remodeling. Among... -
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- Circulating Biologically Active Adrenomedullin Predicts Organ Failure and Mortality in Sepsis
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Kim H, Hur M, Struck J, Bergmann A, Di Somma S
- KMID: 2450968
- Ann Lab Med.
- 2019 Sep;39(5):454-463.
- doi: 10.3343/alm.2019.39.5.454
BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Biologically active adrenomedullin (bio-ADM) is an emerging biomarker for sepsis. We explored whether bio-ADM concentration... -
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- Effect of prostaglandin- and nitric oxide-synthase inhibitors on the lipopolysaccharide-induced adrenomedullin productions in cultured murine macrophage cells
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Koo BS, Won HS, Suh DS, Cho YG, Lee PR, Kim A
- KMID: 1926279
- Korean J Obstet Gynecol.
- 2007 Nov;50(11):1468-1475.
OBJECTIVE: Adrenomedullin (AM), a potent vasorelaxing agent associated with the maintenance of pregnancy, is synthesized in response to inflammation, which is also associated with the biosynthesis of prostaglandin (PG) and... -
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