- Human Leptin Protein Induces Proliferation of A549 Cells via Inhibition of PKR-Like ER Kinase and Activating Transcription Factor-6 Mediated Apoptosis
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Lai Q, Sun Y
- KMID: 1798137
- Yonsei Med J.
- 2013 Nov;54(6):1407-1415.
- doi: 10.3349/ymj.2013.54.6.1407
PURPOSE: To investigate the anti-apoptotic mechanism of leptin in non-small cell lung cancer. MATERIALS AND METHODS: The influences of leptin on apoptosis were investigated, analyzing the mechanism that triggers growth of... -
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- Endoplasmic Reticulum Stress Induces MUC5AC and MUC5B Expression in Human Nasal Airway Epithelial Cells
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Kim MH, Bae CH, Choi YS, Na HG, Song SY, Kim YD
- KMID: 2447427
- Clin Exp Otorhinolaryngol.
- 2019 May;12(2):181-189.
- doi: 10.21053/ceo.2018.00493
OBJECTIVES: Endoplasmic reticulum (ER) stress is known to be associated with inflammatory airway diseases, and three major transmembrane receptors: double-stranded RNA-activated protein kinase-like ER kinase, inositol requiring enzyme 1, and... -
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- Exendin-4 Inhibits the Expression of SEPP1 and Fetuin-A via Improvement of Palmitic Acid-Induced Endoplasmic Reticulum Stress by AMPK
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Lee J, Hong SW, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY
- KMID: 2282008
- Endocrinol Metab.
- 2015 Jun;30(2):177-184.
- doi: 10.3803/EnM.2015.30.2.177
BACKGROUND: Selenoprotein P (SEPP1) and fetuin-A, both circulating liver-derived glycoproteins, are novel biomarkers for insulin resistance and nonalcoholic fatty liver disease. However, the effect of exendin-4 (Ex-4), a glucagon-like peptide-1... -
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