- The Changes of the Visual Evoked Potential for Aconitine Induced Visual Pathway Demyelination in Rabbit Model
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Yoon KC, Kim SH
- KMID: 1950025
- J Korean Ophthalmol Soc.
- 1992 Jun;33(6):622-626.
Aconitine, a principal constituent of aconite, may cause myelopathy on the visual pathway, spinal cord and peripheral nerve of the rabbits. A single dose of aconitine (O.6mg/kg), was administered intraperitoneally... -
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- A case of aconitine poisoning with transient tetraplegia and hypocalcemia
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Lim TH, Park KY
- KMID: 1558499
- Korean J Med.
- 1998 Dec;55(6):1093-1096.
Both "caowu", the root of Aconitum kusnezoffii, "chuanwu", the main root of Aconitum carmichaeli are believed to possess anti-inflammatory, analgesics and cardiotonic effects. They have been used to treat conditions... -
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- Aconitine Intoxication Misdiagnosed as Acute Myocardial Infarction
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Ahn MS
- KMID: 2352415
- Int J Arrhythm.
- 2016 Jun;17(2):103-107.
- doi: 10.18501/arrhythmia.2016.019
A 55-year-old woman was admitted because of sudden onset of chest tightness after ingesting a herbal medicine. She experienced refractory ventricular arrhythmia after admission. Electrocardiography showed ST-segment abnormalities that mimicked... -
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- Rabltit Model of Acenitine Myelo-optic Neuropathy
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Cho HT, Kim SH
- KMID: 2123012
- J Korean Ophthalmol Soc.
- 1991 Apr;32(4):289-293.
A single sublethal dose of aconitine, a principal constituent of aconite, was administered intraperitoneally to evaluate its toxic effects on the visual pathway, spinal cord and peripheral nerve of the... -
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- Experimental Aconitine Neuroretinopathy in Rabbit Eye
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Bae JK, Bae JY, Kwak JS, Kim SH, Seouk KD
- KMID: 2204891
- J Korean Ophthalmol Soc.
- 1988 Apr;29(2):337-345.
Toxic effects of Aconiti tuber, an important ingredient of Chinese medicinal preparation, have been encountered clinically. The chief bioactive and toxic constituent is the alkaloid aconitine. In this study histopathologic... -
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- Experimental Aconitine Optic Neuropathy
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Kim SD, Kim SH
- KMID: 2122962
- J Korean Ophthalmol Soc.
- 1990 May;31(5):661-679.
Effects of aconitine on the retina and optic nerve were studied in rabbits by means of visual evoked potential(VEP), electroretinogram(ERG), and electron microscopy. Aconitine(0.4mg/kg) was administered intra peritoneally. The effects... -
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- A Case of Aconitum Intoxication After Ingestion of a Large Amount of Aconitine Decoction in a Suicide Attempt
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Kim YS, Cho JH, Park CW, Lee HY, Lee BK, Kim HJ, Park SM, Ahn MY
- KMID: 1997760
- J Korean Soc Emerg Med.
- 2010 Oct;21(5):720-723.
Aconitine has been used as a folk remedy for centuries to treat pain and as an inotropic agent. However, because its therapeutic range is very narrow, it often causes many... -
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- An Outbreak of Caowu-intoxication after Drinking Home-brewed Alcohol
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Kim SC, Ha YR, Kim YS, Kim HJ
- KMID: 2332442
- J Korean Soc Emerg Med.
- 2008 Jun;19(3):339-345.
Caowu (aconite) is derived from the roots of certain aconitum species (Racunculaceae), which are widely distributed both in China and Korea. Aconitine, an extremely toxic ingredient present in aconite, has... -
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- Cardiovascular aspects of aconitine poisoning
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Kim WS, Lim SS, Kang HS, Choue CW, Kim KS, Song JS, Bae JH
- KMID: 2227318
- Korean Circ J.
- 2000 Jul;30(7):855-860.
- doi: 10.4070/kcj.2000.30.7.855
BACKGROUND AND OBJECTIVES: The Oriental herbal materials known as aconitine have long been used in oriental traditional medicine for their analgesic and antiinflammatory effects. Aconitine and its related alkaloids are... -
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- A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy
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Shin HJ, Lim H
- KMID: 2328241
- J Korean Soc Clin Toxicol.
- 2016 Jun;14(1):60-65.
Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine.... -
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- A Case of Severe Aconitine Intoxication with Ventricular Tachycardia, Successfully Treated by a Combination of Two Anti-arrhythmic Drugs
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Ryoo SM, Sohn CH, Oh BJ, Kim W, Lim KS
- KMID: 2101644
- J Korean Soc Clin Toxicol.
- 2011 Dec;9(2):105-108.
Aconitine is an anti-inflammatory agent with therapeutic uses in oriental medicine as an analgesic and for treatment of stroke. Because of its sodium channel effect, aconitine can promote undesirable, wide... -
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- Role of the Alternans of Action Potential Duration and Aconitine-Induced Arrhythmias in Isolated Rabbit Hearts
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Jung BC, Lee SH, Cho YK, Park HS, Kim YN, Lee YS, Shin DG
- KMID: 1786013
- J Korean Med Sci.
- 2011 Dec;26(12):1576-1581.
- doi: 10.3346/jkms.2011.26.12.1576
Under conditions of Na+ channel hyperactivation with aconitine, the changes in action potential duration (APD) and the restitution characteristics have not been well defined in the context of aconitine-induced arrhythmogenesis.... -
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- A Case of Successful Resuscitation of 10,150 J Shocks and Therapeutic Hypothermia on Aconitine-induced Cardiovascular Collapse
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Moon HJ, Lee JW, Kim KH, Jeong DK, Kim JH, Kim YK, Lee HJ
- KMID: 2203556
- J Korean Soc Clin Toxicol.
- 2014 Dec;12(2):97-101.
Aconitine, found in the Aconitum species, is highly extremely toxic, and has been known to cause fatal cardiac arrhythmias and cardiovascular collapse. Although several reports have described treatment of aconitine... -
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- Toxicologic Features and Management in Aconitine Intoxication Following Ingestion of Herbal Tablets Containing Aconitum Species
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Cho WL, Jin Y, Jeong TO, Lee JB, Kang JH
- KMID: 2203439
- J Korean Soc Clin Toxicol.
- 2008 Dec;6(2):104-109.
PURPOSE: Unrefined tablets prepared from Aconitum tubers are occasionally used in Korean folk medicine. This study defines the potential sources, clinical toxicology, and treatment of aconitine poisoning. METHODS: A retrospective survey... -
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- Analysis of QTc Prolongation Related to Arrhythmia in Patients with Aconitine Intoxication
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Kim TK, Jin SC, Kim SJ, Choi WI
- KMID: 2191965
- J Korean Soc Emerg Med.
- 2013 Oct;24(5):548-556.
PURPOSE: This study examined the association between the prolongation of heart rate-corrected QT (QTc) and arrhythmia in patients with aconitine intoxication. METHODS: A 13-year retrospective study of patients with aconitine poisoning... -
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- Case of Ventricular Tachycardia After Caowu-Ingestion
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Hyun SC, Kim SR, Park SM, Lee H, Kim KD, Song HS
- KMID: 1999073
- J Korean Soc Emerg Med.
- 1997 Sep;8(3):434-440.
Aconitum species have been used in western and eastern medicine for centuries. In present, chinese medicine uses the drug to treat weak constitution, poor metabolism, dysuria, cardiac weakness, gout rheumatism... -
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- Analysis of cardiovascular change of an Aconitum-containing Chinese Remedy
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Mun JM, Lee BK, Chun BJ, Yoon HD, Heo T, Min YI
- KMID: 1944455
- J Korean Soc Emerg Med.
- 2002 Mar;13(1):55-60.
PURPOSE: The roots of Aconitum plants (e.g.,A carmichaelii, A napellus) have been believed to possess antiinflammatory, analgesic, and cardiotonic effects and have been used in traditional Chinese medicine mainly for... -
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- The Toxicological Studies and Autopsy Findings of Aconitine Poisoning
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Choi HK, Kim YS, Choi IS, Kim JH
- KMID: 2305496
- Korean J Leg Med.
- 2010 May;34(1):15-19.
BACKGROUND: Aconitium species have been used for a material of oriental herb medicine for analgesic and anti-inflammatory effects. But Aconitium species were known to have the potent poisons like aconitine,... -
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- A Case of Aconite Intoxication and Recurrent Ventricular Arrhythmia without Apparent Myocardial Damage after 20,680 Joules DC Shock
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Jin YJ, Lee JH, Choi JH, Na BG, Nam GB, Kim DW, Earm JH, Cho MC, Kim ST
- KMID: 1857690
- Korean Circ J.
- 1997 Jul;27(7):780-786.
- doi: 10.4070/kcj.1997.27.7.780
The aconite root has been used in oriental medicine to improve metabolism of debilitated patient and to cure acute dysuria, cardiac weakness, gout, neuralgias and rheumatism. The crude drug "bu-shi"... -
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- Efficacy of Methylprednisolone in Aconite Induced Myelo-optic Neuropathy in the Rabbit
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Kim IT, Shin JP, Seo HD, Lee SH
- KMID: 2123558
- J Korean Ophthalmol Soc.
- 1996 Oct;37(10):1730-1740.
Studies in animals indicate that aconitine or aconite has toxic effects in the visual system of a rabbit model. Such a toxic effects causes myelo-optic neuropathy in the visually evoked... -
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