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Urinary N-Acetyl-beta-D-Glucosaminidase Activity in Essential Hypertension, Diabetes Mellitus and Renal Disease

Ko JK, Choi EY, Kim HK, Yu KH, Kim JH, Jang DS, Ko KY, Cho KW

NAG activity has been measured in the urine of hypertension, diabetes mellitus and renal disease subjects. Results have shown significantly higher levels of Urinary NAG in hypertension, diaetes and renal...
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O-GlcNAc Modification: Friend or Foe in Diabetic Cardiovascular Disease

Karunakaran U, Jeoung NH

O-Linked beta-N-acetyl glucosaminylation (O-GlcNAcylation) is a dynamic post-translational modification that occurs on serine and threonine residues of cytosolic and nuclear proteins in all cell types, including those involved in the...
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Biomarkers in Acute Kidney Injury

Cho MH

  • KMID: 2196705
  • J Korean Soc Pediatr Nephrol.
  • 2011 Oct;15(2):116-124.
Acute kidney injury (AKI) can result in mortality or progress to chronic kidney disease in hospitalized patients. Although serum creatinine has long been used as the best biomarker for diagnosis...
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N-Acetyl-beta-D-glucosaminidase in acute myocardial infarction

Iqbal MP, Kazmi KA, Jafri HR, Mehboobali N

  • KMID: 1109316
  • Exp Mol Med.
  • 2003 Aug;35(4):275-278.
The objective of the study was to investigate whether the lysosomal enzyme, N-Acetyl-beta-D-glucosaminidase (NAG) activity is increased in plasma of patients with acute myocardial infarction (AMI) and to determine if...
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A Novel Mutation (c.200T>C) in the NAGLU Gene of a Korean Patient with Mucopolysaccharidosis IIIB

Kim YE, Park HD, Jang MA, Ki CS, Lee SY, Kim JW, Cho SY, Jin DK

Mucopolysaccharidosis (MPS) IIIB is a lysosomal storage disorder (LSD) caused by abnormalities of the enzyme alpha-N-acetylglucosaminidase (NAGLU) that is required for degradation of heparan sulfate. The patient in this study...
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Ureteropelvic Junction Obstruction: What We Know and What We Don't Know

Lee H, Han SW

  • KMID: 2311838
  • Korean J Urol.
  • 2009 May;50(5):423-431.
PURPOSE: Ureteropelvic junction (UPJ) obstruction is by far the most common cause of pediatric hydronephrosis. The widespread use of antenatal ultrasonography and modern imaging techniques has resulted in earlier and...
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Urinary N-Acetyl-beta-D-Glucosaminidase and beta 2-Microglobulin in Children with Various Renal Diseases

Yoon SJ, Shin JI, Lee JS, Kim HS

  • KMID: 2197198
  • J Korean Soc Pediatr Nephrol.
  • 2008 Oct;12(2):143-149.
PURPOSE: Urinary N-acetyl-beta-D-glucosaminidase(NAG) and beta 2-microglobulin(B2M) is considered to be a marker of tubulointerstitial injury. The aim of this study was to examine the urinary levels of NAG and B2M...
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Role of Urinary Levels of Endothelin-1, Monocyte Chemotactic Peptide-1, and N-Acetyl Glucosaminidase in Predicting the Severity of Obstruction in Hydronephrotic Neonates

Mohammadjafari H, Rafiei A, Mousavi SA, Alaee A, Yeganeh Y

PURPOSE: Antenatal hydronephrosis (AH) is found in 0.5%-1% of neonates. The aim of the study was to assess the urinary concentrations of 3 biomarkers, endothelin-1 (ET-1), monocyte chemotactic peptide-1 (MCP-1),...
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A Study of the Correlation Between the Activity of Erythrocyte Pyrimidine 5'-Nucleotidase and Urinary N-Acetyl-beta-D-Glucosaminidase in Lead Exposed Workers

Chang SH, Hwang CH, Lee WJ, Lee SS, Lee BK, Suh HK, Choi JW

  • KMID: 2141574
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):258-266.
In this study, we measured the activity of the erythrocyte pyrimidine 5'-nucleotidase (P5N) and urinary N-acetyl-beta-D-glucosaminidase (NAG) from 154 workers exposed to lead and 43 workers not exposed. We analyzed...
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Renal Dysfunction Indicators in Lead Exposed Workers

Lee SJ, Hong YS, Kim SR, Kim DI, Kim JY, Jung KY

  • KMID: 2027945
  • Korean J Occup Environ Med.
  • 1996 Sep;8(2):340-349.
A range of indicators is available to assess renal dysfunction in lead exposure. This study was undertaken to find out which indicators were most valuable as markers of renal dysfunction....
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A case of mucolipidosis II presenting with prenatal skeletal dysplasia and severe secondary hyperparathyroidism at birth

Heo JS, Choi KY, Sohn SH, Kim C, Kim YJ, Shin SH, Lee JM, Lee J, Sohn JA, Lim BC, Lee JA, Choi CW, Kim EK, Kim HS, Kim BI, Choi JH

Mucolipidosis II (ML II) or inclusion cell disease (I-cell disease) is a rarely occurring autosomal recessive lysosomal enzyme-targeting disease. This disease is usually found to occur in individuals aged between...
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Biological Indices for Early Detection of Cadmium Poisoning: Significance of Urinary Metallothionein

Park JD, Hong YP, Chang IW

  • KMID: 2141572
  • Korean J Occup Environ Med.
  • 1997 Jun;9(2):230-243.
Metallothionein(MT) is a low molecular weight protein that is induced as a defence mechanism for cadmium (Cd) toxicity. In present study, urinary MT was determined using a competitive ELISA in...
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Evaluation of the Optimal Frequency of and Pretreatment with Shock Waves in Patients with Renal Stones

Lee JY, Moon YT

  • KMID: 2315404
  • Korean J Urol.
  • 2011 Nov;52(11):776-781.
PURPOSE: Many studies have been carried out to increase the success rate of shock wave lithotripsy (SWL) and to reduce renal injury. We investigated the success rate after one session...
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Effect of Intravenous Immunoglobulin(IVIG) on Renal Function in Very Low Birth Weight Infants

Jang HY, Kim HM

  • KMID: 2104250
  • J Korean Pediatr Soc.
  • 1996 Apr;39(4):475-481.
PURPOSE: This study was conducted to evaluate the effect of IVIG infusion on renal function in VLBW infants. IVIG has been proved quite safe in neonates given prophylactic and therapeutic...
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A Study on Urinary N-acetyl-beta-D-glucosaminidase Activities of Office Workers in a Certain Industrial Complex Area

Kim HS, Lee GS, Lee SS, Ahn KD, Lee BK

  • KMID: 2282702
  • Korean J Prev Med.
  • 1994 Sep;27(3):547-556.
In order to identify the necessary information of biochemical indices for renal effect of lead for the early detection in medical surveillance of lead worker, the reference values of urinary...
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Clinical Significance of N-Acetyl-beta-D-glucosaminidase in the Patients of Non-insulin-dependent Diabetes

Jeon CH, Suh HS

  • KMID: 2039318
  • Korean J Clin Pathol.
  • 1997 Feb;17(1):47-54.
BACKGROUND: Routine renal function tests are not sensitive enough to detect early renal complication of diabetes. To detect the complication as soon as possible, we measured urine N-Acetyl-beta-D-glucosaminidase(NAG) and evaluated...
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Assessment of renal function in silicosis with urinary N-acetyl-beta-D-glucosaminidase activity

Lee HR, Kim DK, Lee SI, Cho BM, Kim WJ

  • KMID: 2282620
  • Korean J Prev Med.
  • 1993 Mar;26(1):49-64.
To provide the basic for assessment of renal dysfunction related to silicosis, urinary N-acetyl-beta-D-glucosaminidase(NAG) activity known as a sensitive markers for early renal damage were measured in 58 silicosis patients,...
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Effects of Dapagliflozin on Endothelial Function, Renal Injury Markers, and Glycemic Control in Drug-Naïve Patients with Type 2 Diabetes Mellitus

Kong SH, Koo BK, Moon MK

BACKGROUND: The study aimed to evaluate the effects of dapagliflozin and metformin on vascular endothelial function and renal injury markers. METHODS: This prospective, randomized, open-label, crossover study included drug-naïve patients with...
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Urinary Protein and Enzyme Excretion of Spot Urine in Children with Vesicoureteral Reflux

Yoon JR, Koo JW

  • KMID: 2197130
  • J Korean Soc Pediatr Nephrol.
  • 2009 Apr;13(1):56-62.
PURPOSE: The aim of this study was to evaluate the clinical usefulness of measurement of beta2 microglobulin (beta2 MG), N-acetyl-beta-D-glucosaminidase (NAG) of spot urine samples as indices of renal tubular...
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A Study on Urinary Cadmium Concentration and Renal Indices of Inhabitant in an Abandoned Mine Area

Park JD, Park CB, Choi BS, Kang EY, Hong YP, Chang IW, Chun BY, Yeh MH

  • KMID: 2282941
  • Korean J Prev Med.
  • 1998 Aug;31(3):424-439.
Urinary cadmium is used as a sensitive indicator for internal Cd dose, and increased excretion of N-acetyl-beta-D-glucosaminidase(NAG), beta(2)microglobulin(MG) and total protein are useful indices for renal dysfunction by chronic exposure...
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