- Antioxidant Effects of Sulfur-Containing Amino Acids
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Atmaca G
- KMID: 1103898
- Yonsei Med J.
- 2004 Oct;45(5):776-788.
- doi: 10.3349/ymj.2004.45.5.776
Sulfur is an essential element for the entire biological kingdom because of its incorporation into amino acids, proteins and other biomolecules. Sulfur atoms are also important in the iron-containing flavoenzymes.... -
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- Hydrogen peroxide mediates doxorubicin-induced transglutaminase 2 expression in PC-14 human lung cancer cell line
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Han JA, Park SC
- KMID: 1029936
- Exp Mol Med.
- 1999 Jun;31(2):83-88.
Increased expression of Transglutaminases 2 (TGase 2, TGase C) was observed in PC-14 human lung cancer cells in association with doxorubicin resistance and the reduction of the enzyme expression was correlated with... -
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- Sulforaphane Induces Antioxidative and Antiproliferative Responses by Generating Reactive Oxygen Species in Human Bronchial Epithelial BEAS-2B Cells
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Lee YJ, Lee SH
- KMID: 1123448
- J Korean Med Sci.
- 2011 Nov;26(11):1474-1482.
- doi: 10.3346/jkms.2011.26.11.1474
Sulforaphane (SFN) is a naturally occurring compound which is known to induce the phase II antioxidant genes via Nrf2 activation, although the underlying mechanism has not been fully elucidated. In... -
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- Sodium tanshinone IIA sulfonate attenuates angiotensin II-induced collagen type I expression in cardiac fibroblasts in vitro
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Yang L, Zou XJ, Gao X, Chen H, Luo JL, Wang ZH, Liang QS, Yang GT
- KMID: 1058025
- Exp Mol Med.
- 2009 Jul;41(7):508-516.
- doi: 10.3858/emm.2009.41.7.056
Cardiac fibrosis occurs after pathological stimuli to the cardiovascular system. One of the most important factors that contribute to cardiac fibrosis is angiotensin II (Ang II). Accumulating studies have suggested... -
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- Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells
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Song IS, Jeong YJ, Jeong SH, Heo HJ, Kim HK, Lee SR, Ko TH, Youm JB, Kim N, Ko KS, Rhee BD, Han J
- KMID: 2154269
- Exp Mol Med.
- 2013 Oct;45(10):e50.
Bortezomib is a proteasome inhibitor used for the treatment of relapsed/refractory multiple myeloma (MM). However, intrinsic and acquired resistance to bortezomib has already been observed in MM patients. In a... -
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- Protective effects of fustin, a flavonoid from Rhus verniciflua tokes, on 6-hydroxydopamine-induced neuronal cell death
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Park BC, Lee YS, Park HJ, Kwak MK, Yoo BK, Kim JY, Kim JA
- KMID: 1047082
- Exp Mol Med.
- 2007 Jun;39(3):316-326.
6-Hydroxydopamine (6-OHDA) is a neurotoxin and is commonly used to generate experimental models of Parkinson's disease (PD). In this study, we investigated the signaling molecules involved in the 6-OHDA-induced cell... -
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- Involvement of ROS and JNK1 in selenite-induced a poptosisin Chang liver cells
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Kim YS, Jhon DY, Lee KY
- KMID: 1380210
- Exp Mol Med.
- 2004 Apr;36(2):157-164.
Selenium is a dietary essential trace nutrient with important biological roles. Selenocompounds were reported to induce apoptosis in many types of tumor cells. In this study, we investigated the signaling... -
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- Partial purification of protein farnesyl cysteine carboxyl methyltransferase from bovine brain
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Yoo BC, Kang MS, Kim SD, Lee YS, Choi SY, Ryu CK, Park GH, Han JS
- KMID: 755013
- Exp Mol Med.
- 1998 Dec;30(4):227-234.
C-terminal farnesyl cysteine carboxyl methylation has been known to be the last step in the post-translational modification processes of several important signal transduction proteins in eukaryotes including ras related GTP... -
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- Methylglyoxal Induces Apoptosis Mediated by Reactive Oxygen Species in Bovine Retinal Pericytes
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Kim J, Son JW, Lee JA, Oh YS, Shinn SH
- KMID: 1785701
- J Korean Med Sci.
- 2004 Feb;19(1):95-100.
- doi: 10.3346/jkms.2004.19.1.95
One of the histopathologic hallmarks of early diabetic retinopathy is the loss of pericytes. Evidences suggest that the pericyte loss in vivo is mediated by apoptosis. However, the underlying cause... -
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