- High glucose, unsaturated and saturated fatty acids differentially regulate expression of ATP-binding cassette transporters ABCA1 and ABCG1 in human macrophages
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Mauerer R, Ebert S, Langmann T
- KMID: 1109435
- Exp Mol Med.
- 2009 Feb;41(2):126-132.
- doi: 10.3858/emm.2009.41.2.015
The ATP-binding cassette transporters ABCA1 and ABCG1 are highly expressed in macrophage-derived foam cells and promote reverse cholesterol efflux via biogenesis of high-density lipoproteins. The aim of this study was... -
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- Isolated Cerebellar Variant of Adrenoleukodystrophy with a de novo Adenosine Triphosphate-Binding Cassette D1 (ABCD1) Gene Mutation
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Kang JW, Lee SM, Koo KY, Lee YM, Nam HS, Quan Z, Kang HC
- KMID: 2130847
- Yonsei Med J.
- 2014 Jul;55(4):1157-1160.
- doi: 10.3349/ymj.2014.55.4.1157
X-linked adrenoleukodystrophy (X-ALD) shows a wide range of phenotypic expression, but clinical presentation as an isolated lesion of the cerebellar white matter and dentate nuclei has not been reported. We... -
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- TAP1 and TAP2 Gene Polymorphisms in Korean Patients with Allergic Rhinitis
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Kim KR, Cho SH, Choi SJ, Jeong JH, Lee SH, Park CW, Tae K
- KMID: 1713288
- J Korean Med Sci.
- 2007 Oct;22(5):825-831.
- doi: 10.3346/jkms.2007.22.5.825
Antigen peptides are actively transported across the endoplasmic reticulum by the transporters associated with antigen presentation (TAP). TAP genes polymorphism could influence the selection process that determines which antigen peptides... -
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- Novel insertion mutation of ABCB1 gene in an ivermectin-sensitive Border Collie
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Han JI, Son HW, Park SC, Na KJ
- KMID: 1072184
- J Vet Sci.
- 2010 Dec;11(4):341-344.
- doi: 10.4142/jvs.2010.11.4.341
P-glycoprotein (P-gp) is encoded by the ABCB1 gene and acts as an efflux pump for xenobiotics. In the Border Collie, a nonsense mutation caused by a 4-base pair deletion in... -
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- Interferon-Stimulated Genes Response in Endothelial Cells Following Hantaan Virus Infection
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Kim IW, Hwang JY, Kim SK, Kim JK, Park HS
- KMID: 1785758
- J Korean Med Sci.
- 2007 Dec;22(6):987-992.
- doi: 10.3346/jkms.2007.22.6.987
The regulation mechanism of interferon (IFN) and IFN-stimulated genes is a very complex procedure and is dependent on cell types and virus species. We observed molecular changes related to anti-viral... -
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- Genetic analysis of ABCG2 and SLC2A9 gene polymorphisms in gouty arthritis in a Korean population
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Kim YS, Kim Y, Park G, Kim SK, Choe JY, Park BL, Kim HS
- KMID: 2381597
- Korean J Intern Med.
- 2015 Nov;30(6):913-920.
- doi: 10.3904/kjim.2015.30.6.913
BACKGROUND/AIMS: Gout is a common inf lammatory arthritis triggered by the crystallization of uric acid in the joints. Serum uric acid levels are highly heritable, suggesting a strong genetic component.... -
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- Adenovirus adenine nucleotide translocator-2 shRNA effectively induces apoptosis and enhances chemosensitivity by the down-regulation of ABCG2 in breast cancer stem-like cells
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Jang JY, Kim MK, Jeon YK, Joung YK, Park KD, Kim CW
- KMID: 1365902
- Exp Mol Med.
- 2012 Apr;44(4):251-259.
- doi: 10.3858/emm.2012.44.4.019
Cancer stem cells (CSCs) are resistant to chemo- and radio-therapy, and can survive to regenerate new tumors. This is an important reason why various anti-cancer therapies often fail to completely... -
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