- Effect of diazepam on haloperidol-induced DOPAC increase in the rat brain
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Park YN, Kim SK, Lee SR, Cho SW
- KMID: 2197775
- J Korean Neuropsychiatr Assoc.
- 1993 Mar;32(2):178-187.
No abstract available. -
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- Effect of bromocriptine on 6-hydroxydopamine-induced lipid peroxidation and cytotoxicity in vitro and in vivo
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Kim YS, Maeng S, Park CW
- KMID: 2071536
- Korean J Physiol Pharmacol.
- 1998 Oct;2(5):565-572.
The present study was to evaluate the protective effects of bromocriptine, which is known as D2 dopamine receptor agonist and used for the treatment of patients with Parkinson's disease (PD), on 6-hydroxydopamine (6-OHDA)-induced... -
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- Effects of (−)-Sesamin on Memory Deficits in MPTP-lesioned Mouse Model of Parkinson's Disease
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Zhao TT, Shin KS, Lee MK
- KMID: 2366691
- Nat Prod Sci.
- 2016 Dec;22(4):246-251.
- doi: 10.20307/nps.2016.22.4.246
This study investigated the effects of (−)-sesamin on memory deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model of Parkinson's disease (PD). MPTP lesion (30 mg/kg/day, 5 days) in mice showed memory deficits... -
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- Effects of Gypenosides on Dopaminergic Neuronal Cell Death in 6-Hydroxydopamine-lesioned Rat Model of Parkinson's Disease with Long-term L-DOPA Treatment
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Shin KS, Zhao TT, Park HJ, Kim KS, Choi HS, Lee MK
- KMID: 2355144
- Nat Prod Sci.
- 2016 Sep;22(3):187-192.
- doi: 10.20307/nps.2016.22.3.187
The goal of this study was to determine whether gypenosides (GPS) exert protective effects against dopaminergic neuronal cell death in a 6-hydroxydopamine (OHDA)-lesioned rat model of Parkinson's disease (PD) with... -
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- Relationship Between Changes of Biogenic Amines and Free Radicals in the Ischemia/Reperfusion Injury of Rat Brain
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Lee KE, Kim KH
- KMID: 1686760
- J Korean Neurol Assoc.
- 1993 Sep;11(3):329-340.
After the ischemic episode. A new cerebral damage can occur during the restitution of blood flow. Oxygen free radicals. Formed during ischemia/reperfusion. Have been proposed as one of the main... -
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- Characterization of Norepinephrine Release in Rat Posterior Hypothalamus Using in vivo Brain Microdialysis
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Sung KW, Kim SY, Kim ON, Lee SB
- KMID: 1614852
- Korean J Physiol Pharmacol.
- 2002 Feb;6(1):9-14.
In the present study, we used the microdialysis technique combined with high performance liquid chromatography (HPLC) and electrochemical detection to measure the extracellular levels of norepinephrine (NE) in the posterior... -
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- Effect of Hypoxia-Ischemia on Striatal Monoamine Metabolism in Neonatal Rat Brains
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Jee YH, Kim HG, Park WS, Chang YP
- KMID: 1606964
- J Korean Pediatr Soc.
- 2003 Aug;46(8):789-794.
PURPOSE: We intended to evaluate the effect of hypoxia-ischemia on extracellular striatal monoamine metabolism in neonatal rat brains by in vivo microdialysis. METHODS: The right common carotid arteries of five or... -
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- Reduction of Central Dopamine Release in Hyperprolactinemia
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Cha BS, Song YD, Lim SK, Kim KR, Lee HC, Huh KB, Nam SY, Lee EJ, Chung BC, Kim JH, Oh SC
- KMID: 2461633
- J Korean Soc Endocrinol.
- 1996 Sep;11(3):277-284.
Background: Prolactin(PRL) secretion is tonically inhibited by doparnine that originates from the hypothalamic tuberoinfundibular tract and reaches the lactotroph via the hypophyseal portal vessel. Hyperprolactinemia associated with oligomenorrhea-amenorrhea, galactorrhea and/or... -
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- Monoaminergic Activity by Drugs Acting on Adrenergic alpha2-receptors in Rat Hippocampus and Primary Visual Cortex
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Kim HG, Lee YC, Paik KC, Lim MH, Kim HW, Kang BJ
- KMID: 2286867
- Korean J Psychopharmacol.
- 2004 Sep;15(3):371-379.
OBJECTIVE: The aim of the this study was to compare the effects of clonidine (a alpha2-adrenoceptor and imidazoline receptor agonist), yohimbine (a selective alpha2-adrenoceptor antagonist) and idazoxan (a alpha2-adrenoceptor and... -
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- Study of dopamine transporter in the rat 6-hydroxydopamine Parkinson's disease model
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Kim SY, Jung JM, Chang YS, Joo WS, Maeng SH, Ha CG, Kim JM, Kim YS, Lee MC, Lee SB, Jeon BS
- KMID: 2342701
- J Korean Neurol Assoc.
- 1998 Aug;16(4):536-546.
BACKGROUND: Neuroprotective therapy is essential in the management of Parkinson's disease(PD). As symptomatic benefit of a treatment may clinically mask the disease progression, an evaluation of the effect of a... -
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- Effects of Chronic Alcohol Exposure on Dopaminergic and Serotonergic Neurotransmission System in Rat
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Park SW, Lee YC, Ha EK, Kim YK, Lee YK, Chung DO, Ryu JW, Kong BG, Kim YH
- KMID: 2287358
- Korean J Psychopharmacol.
- 2005 Jan;16(1):81-90.
OBJECTIVE: This study investigates the effects of chronic alcohol exposure on rat brain THmRNA expression, TH (tyrosine hydroxylase) acitivity, and TPH (tryptophan hydroxylase) activity which are important in synthesis of... -
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- Relationship of the Changes in Biogenic Amines to Nitric Oxide and Oxygen Free Radicals During Cerebral Ischemia/Reperfusion
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Moon JS, Jung HS, Kim DG, Kim KH, Lee BC
- KMID: 2066001
- J Korean Neurol Assoc.
- 1995 Dec;13(4):773-787.
Recently oxygen free radicals and nitric oxide (NO) are known to play an important role in neuronal reperfusion injury. This study was aimed to investigate the role of oxygen f... -
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