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Insulin Resistance in Non-Alcoholic Fatty Liver Disease

Park JH

  • KMID: 760627
  • Korean J Hepatol.
  • 2006 Mar;12(1):16-30.
Insulin resistance is the pathophysiological hallmark of various kinds of clinical diseases, including non- alcoholic fatty liver disease. Insulin resistance is the common characteristic of metabolic syndrome and its related...
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beta-Cell dysfunction and insulin resistance in gestational glucose intolerance

Jang EH, Kwon HS

No abstract available.
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Chronic Hepatitis C and Insulin Resistance

Chung WJ

Insulin resistance is frequently associated with chronic liver disease, and the interaction between hepatitis C virus (HCV) infection and insulin resistance is a major public health issue, bound to increase...
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Effects of phlorizin and acipimox on insulin resistance in STZ-diabetic rats

Kim YW, Kim JY, Lee SK

To evaluate the roles of hyperglycemia and increased plasma FFA level in the development of insulin resistance, we examined the effects of phlorizin and acipimox treatments on tissue sensitivity to...
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Modulation of the caveolin-3 and Akt status in caveolae by insulin resistance in H9c2 cardiomyoblasts

Ha H, Pak Y

  • KMID: 1056228
  • Exp Mol Med.
  • 2005 Jun;37(3):169-178.
We investigated glucose uptake and the translocation of Akt and caveolin-3 in response to insulin in H9c2 cardiomyoblasts exposed to an experimental insulin resistance condition of 100 nM insulin in...
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Insulin Secretion and Sensitivity during Oral Glucose Tolerance Test in Korean Lean Elderly Women

Kim J, Choi S, Kong B, Oh Y, Shinn S

Impaired glucose tolerance (IGT) and type 2 diabetes including undiagnosed isolated postchallenge hyperglycemia (IPH) are common in the elderly. The aim of this study was to investigate the insulin secretion...
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Obesity, Insulin Resistance, and the Risk of Colonic Adenoma

Kim TO, Song GA

  • KMID: 782844
  • Korean J Gastroenterol.
  • 2007 Mar;49(3):192-195.
No abstract availble.
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Obesity, Insulin Resistance and Cancer Risk

Jee SH, Kim HJ, Lee J

Obesity is a known cause of metabolic syndrome which includes Type II diabetes, hypertension, and dyslipidemia. It is well documented that insulin resistance contributes to the mortality and the incidence...
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Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea

Park JS, Kim CS, Nam JY, Kim DM, Jo MH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC, Huh KB

The aim of this study was to assess the implications of insulin resistance on the clinical and biochemical profiles of Korean type 2 diabetic patients. 122 patients with type 2...
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Effect of High Fat Diet on Insulin Resistance: Dietary Fat Versus Visceral Fat Mass

Park SY, Kim YW, Kim JY, Jang EC, Doh KO, Lee SK

The purpose of the present study was to determine whether chronic high-fat diet (HF) induces insulin resistance independently of obesity. We randomly divided 40 rats into two groups and fed...
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Elevated Insulin and Insulin Resistance Are Associated with the Advanced Pathological Stage of Prostate Cancer in Korean Population

Yun SJ, Min BD, Kang HW, Shin KS, Kim TH, Kim WT, Lee SC, Kim WJ

The study was designed to investigate the effect of serum glucose, insulin and insulin resistance on the risk of prostate cancer (CaP) and on the clinicopathological characteristics in Korean men....
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Insulin Resistance is Associated with Gallstones Even in Non-obese, Non-diabetic Korean Men

Chang Y, Sung E, Ryu S, Park YW, Jang YM, Park M

It remains unclear as to whether insulin resistance alone or in the presence of wellknown risk factors, such as diabetes or obesity, is associated with gallstones in men. The aim...
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Is Insulin Resistance an Intrinsic Defect in Asian Polycystic Ovary Syndrome?

Lee H, Oh JY, Sung YA, Chung H

PURPOSE: Approximately 50% to 70% of women with polycystic ovary syndrome (PCOS) have some degree of insulin resistance, and obesity is known to worsen insulin resistance. Many metabolic consequences of...
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Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome

Kim B, Feldman EL

Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that includes obesity, diabetes, and dyslipidemia. Accumulating evidence implies that MetS contributes to the development and progression of Alzheimer's disease...
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O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes

Park SY, Ryu J, Lee W

  • KMID: 1056235
  • Exp Mol Med.
  • 2005 Jun;37(3):220-229.
It has been known that O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of proteins plays an important role in transcription, translation, nuclear transport and signal transduction. The increased flux of glucose through the...
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Adipokines, insulin-like growth factor binding protein-3 levels, and insulin sensitivity in women with polycystic ovary syndrome

Lee H, Oh JY, Sung YA

BACKGROUND/AIMS: Many women with polycystic ovary syndrome (PCOS) exhibit insulin resistance. Adipose tissue plays an important role in insulin resistance, and adipokines including tumor necrosis factor (TNF)-alpha and adiponectin are...
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The Relation between Birth Weight and Insulin Resistance in Korean Adolescents

Kim CS, Park JS, Park J, Nam JS, Kang ES, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC, Huh KB, Kim DJ

Low birth weight is associated with insulin resistance and type 2 diabetes in adults. The fetal programming hypothesis has shown that insulin resistance and its associated metabolic disturbances result from...
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The Effect of Cilostazol on Glucose Tolerance and Insulin Resistance in a Rat Model of Non-insulin Dependent Diabetes Mellitus

Chang SA, Cha BY, Yoo SJ, Ahn YB, Song KH, Han JH, Lee JM, Son HS, Yoon KH, Kang MI, Lee KW, Son HY, Kang SK

  • KMID: 938272
  • Korean J Intern Med.
  • 2001 Jun;16(2):87-92.
BACKGROUND: It has been reported that many peripheral vasodilating drugs might improve insulin resistance. Cilostazol, a antithrombotic agent, increases peripheral blood flow in non-insulin dependent diabetic patients. The effect...
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Differences in Insulin Sensitivity and Secretory Capacity Based on OGTT in Subjects with Impaired Glucose Regulation

Rhee SY, Kwon MK, Park BJ, Chon S, Jeong IK, Oh S, Ahn KJ, Chung HY, Kim SW, Kim JW, Kim YS, Woo JT

BACKGROUND: This study examined whether defects in insulin secretion contribute to the development and progression of type 2 diabetes mellitus (T2DM). METHDOS: Plasma insulin and glucose were measured...
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Association between Insulin, Insulin Resistance, and Gallstone Disease in Korean General Population

Kim JM, Lee HL, Moon W, Koh DH, Lee OY, Yoon BC, Choi HS, Hahm JS, Lee MH, Lee DH, Ahn YH

  • KMID: 782910
  • Korean J Gastroenterol.
  • 2007 Sep;50(3):183-187.
BACKGROUND/AIMS: Diabetes is one of the risk factors of gallstone diseases. Many studies found a positive association between insulin and gallstones in individuals with diabetes. However, this association is...
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