- Immunoglobulin and T-cell receptor gene rearrangement analysis in malignant lymphoid neoplasms
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Park CK, Kim CW, Kim IS, Lee JD
- KMID: 644822
- J Korean Med Sci.
- 1994 Oct;9(5):362-368.
- doi: 10.3346/jkms.1994.9.5.362
Gene rearrangement analysis using Southern-blot hybridization technique is a standard method for evaluating clonal receptor gene rearrangement. Both clonality and lineage can be identified in lymphoid neoplasms by the demonstration... -
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- Submicroscopic Deletions of Immunoglobulin Heavy Chain Gene (IGH) in Precursor B Lymphoblastic Leukemia with IGH Rearrangements
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Huh J, Mun YC, Yoo ES, Seong CM, Chung WS
- KMID: 2363160
- Ann Lab Med.
- 2015 Jan;35(1):128-131.
- doi: 10.3343/alm.2015.35.1.128
Translocations leading to fusions between the immunoglobulin heavy chain gene (IGH) and various partner genes have been reported in B-cell precursor acute lymphoblastic leukemia (B-ALL). However, submicroscopic deletions within IGH... -
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- Molecular Cytogenetic Analysis of Gene Rearrangements in Childhood Acute Lymphoblastic Leukemia
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Woo HY, Kim DW, Park H, Seong KW, Koo HH, Kim SH
- KMID: 1781721
- J Korean Med Sci.
- 2005 Feb;20(1):36-41.
- doi: 10.3346/jkms.2005.20.1.36
The aims of this study were to estimate the incidences of BCR/ABL, MLL, TEL/AML1 rearrangements, and p16 deletions in childhood acute lymphoblastic leukemia (ALL), to identify new abnormalities, and to... -
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- Diagnostic Usefulness of Genomic Breakpoint Analysis of Various Gene Rearrangements in Acute Leukemias: A Perspective of Long Distance- or Long Distance Inverse-PCR-based Approaches
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Yang JJ, Marschalek R, Meyer C, Park TS
- KMID: 1380095
- Ann Lab Med.
- 2012 Jul;32(4):316-318.
- doi: 10.3343/alm.2012.32.4.316
No abstract available. -
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- A Case of Lambda-expressing Pulmonary MALT Lymphoma with Dual Clonal Rearrangements of Kappa and Lambda Immunoglobulin Light Chain Gene
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Oh HR, Lee MJ, Park G, Moon DS, Park YJ, Jang SJ
- KMID: 1096979
- Korean J Lab Med.
- 2009 Jun;29(3):256-261.
- doi: 10.3343/kjlm.2009.29.3.256
A 70-yr-old woman was hospitalized with a history of dry cough. Bronchial endoscopy and transbronchial lung biopsy were performed. However, the findings of histopathology and immunohistochemistry were not sufficient to... -
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- EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells
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Chang H, Sung JH, Moon SU, Kim HS, Kim JW, Lee JS
- KMID: 2374183
- Yonsei Med J.
- 2017 Jan;58(1):9-18.
- doi: 10.3349/ymj.2017.58.1.9
PURPOSE: Rearrangement of the proto-oncogene rearranged during transfection (RET) has been newly identified potential driver mutation in lung adenocarcinoma. Clinically available tyrosine kinase inhibitors (TKIs) target RET kinase activity, which... -
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