Korean J Med Mycol.  2010 Mar;15(1):1-11.

A Study on the Antimicrobial Effect of Bamboo (Phyllosrachys bambusoides) Essential Oil on Malassezia

Affiliations
  • 1Department of Food Engineering, Dankook University, Cheonan, Korea.
  • 2Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea. beomjoon@unitel.co.kr
  • 3Daebong Life Science, Incheon-City, Korea.
  • 4Department of Dermatology, Seoul National University College of Medicine, Korea.
  • 5Department of Genetic Engineering and Skin Biotechnology Center, College of Life Science, Kyung Hee University, Suwon, Korea.

Abstract

BACKGROUND
Malassezia is considered as major factor in dandruff of human scalp.
OBJECTIVE
In order to develop an antimicrobial agent, bamboo oil was extracted by high temperture suction from dried bamboo truk abd then antimicrobial activities against Malassezia are investigated.
METHODS
Minimum inhibitory concentration and antimicrobial activity were measured in Malassezia species.
RESULTS
1. Minimum inhibitory concentration of the Bamboo (Phyllosrachys bambusoides) Essential Oil Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis standard, Malassezia sympodialis patient, Malassezia dermatis standard, Malassezia dermatis patient were 10 microliter/ml, 5 microliter/ml, 5 microliter/ml, 10 microliter/ml, 5 microliter/ml and 10 microliter/ml respectively. 2. Minimum inhibitory concentration of the Itraconazole Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis standard, Malassezia sympodialis patient, Malassezia dermatis standardntia, Malassezia dermatis patient were 10 microgram/ml, 10 microgram/ml, 10 microgram/ml, 0.1 microgram/ml, 1 microgram/ml, and 0.01 microgram/ml, respectively. 3. Minimum inhibitory concentration of the ketoconazole Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis standard, Malassezia sympodialis patient, Malassezia dermatis standard, Malassezia dermatis patient were 0.01 microgram/ml, 10 microgram/ml, 10 microgram/ml, 0.1 microgram/ml, 0.01 microgram/ml, and 0.01 microgram/ml, respectively. 4. Malassezia furfur standard, Malassezia furfur patient, Malassezia sympodialis patient and Malassezia dermatis patient showed the strongest antimicrobial effect on bamboo oil > ketoconazole > itraconazole. 5. Malassezia sympodialis standard, Malassezia sympodialis patient and Malassezia dermatis standard strongest antimicrobial effect on ketoconazole > bamboo oil > itraconazole.
CONCLUSION
Bamboo oil might be applied as antidandruff treatment modality by its anti-malassezial effect.

Keyword

Bamboo oil; Itraconazole; Ketoconazole; Minimum inhibitory concentration; Antimicrobial effect; Malassezia

MeSH Terms

Humans
Itraconazole
Ketoconazole
Malassezia
Microbial Sensitivity Tests
Scalp
Suction
Itraconazole
Ketoconazole
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