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Loss of EMP2 Inhibits Melanogenesis of MNT1 Melanoma Cells via Regulation of TRP-2

Enkhtaivan E, Kim HJ, Kim B, Byun HJ, Yu L, Nguyen TM, Nguyen TH, Do PA, Kim EJ, Kim KS, Huy HP, Rahman M, Jang JY, Rho SB, Lee H, Kang GJ, Park MK, Kim NH, Choi CI, Lee K, Han HK, Cho J, Lee AY, Lee CH

Melanogenesis is the production of melanin from tyrosine by a series of enzyme-catalyzed reactions, in which tyrosinase and DOPA oxidase play key roles. The melanin content in the skin determines...
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Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation

Rho SB, Byun HJ, Kim BR, Lee CH

Metformin is an anti-diabetic drug and has anticancer effects on various cancers. Several studies have suggested that metformin reduces cell proliferation and stimulates cell-cycle arrest and apoptosis. However, the definitive...
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Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer

Rho SB, Lee KW, Lee SH, Byun HJ, Kim BR, Lee CH

The imprinted tumour suppressor NOEY2 is downregulated in various cancer types, including ovarian cancers. Recent data suggest that NOEY2 plays an essential role in regulating the cell cycle, angiogenesis and...
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Immunohistochemical Analysis of Prurigo Nodularis in 209 Patients: Clinicopathological Analysis between Atopic and Non-Atopic Patients and between Treatment Response Groups

Byun HJ, Jang D, Lee DY, Yang JM

Background: Prurigo nodularis (PN) is a highly pruritic disease that significantly impairs patient quality of life. Although the mechanism that causes pruritus is not clear, one hypothesis argues that neural...
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A Case Report of Multiple Capillary Hemangioma in a Chronic Myeloid Leukemia Patient Taking Tyrosine Kinase Inhibitors

Byun HJ, Jang D, Lee J, Oh SJ, Lim Y, Park JH, Lee JH, Lee DY

A capillary hemangioma is a vascular tumor with small capillary sized vascular channel. Multiple capillary hemangioma in relation with drugs have been rarely reported. Here in, we report a case...
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Combination Treatment of Intra/Perilesional Botulinum Toxin-A Injection and Ablative Fractional Laser for Better Clinical Outcomes of Hypertrophic Fibrotic Thyroidectomy Scars Following Fractional Ablative Laser Resurfacing

Byun HJ, Park JH, Lee JH

Background: Recent reports have shown that intralesional botulinum toxin type-A (BTX-A) works on scar cosmesis. Objective: To evaluate the clinical efficacy of combination treatment of laser and BTX-A injection and compare...
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HOTAIR Induces Methylation of PCDH10, a Tumor Suppressor Gene, by Regulating DNMT1 and Sponging with miR-148b in Gastric Adenocarcinoma

Seo SI, Yoon JH, Byun HJ, Lee SK

Purpose HOX transcript antisense intergenic RNA (HOTAIR), as a long non-coding RNA, has been reported to regulate carcinogenesis by epigenetic mechanism in various cancers. Protocadherin 10 (PCDH10) is one of the...
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Two Cases of Multiple Epidermolytic Acanthomas Mimicking Verruca Vulgaris

Lee DY, Byun HJ, Jang Dh, Lee Je, Oh SJ, Park JH

Epidermolytic acanthoma (EA) is a rare benign tumor, which usually appears as a solitary small papule. However, there are a few case reports of multiple EA, most of which occurs...
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LUCAT1 Epigenetically Downregulates the Tumor Suppressor Genes CXXC4 and SFRP2 in Gastric Cancer

Byun HJ, Yoon JH, Lee SK

Purpose: The mechanisms of Wnt/β-catenin pathway signaling and abnormal expression of tumor suppressor genes is not well known in gastric cancer (GC). Long non-coding RNA (lncRNA) has recently been identified...
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A Retrospective Clinicopathologic Study of KoreanPatients with Cutaneous Peripheral T-Cell LymphomaNot Otherwise Specified at a Single Tertiary Center

Park JH, Choi Y, Byun HJ, Oh SJ, Lee JH, Lee DY

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Psoriasiform Dermatitis Related with T-Cell Immunoreceptor with Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domains Inhibitor in a Patient with Non-Small-Cell Lung Cancer

Choi Y, Jang D, Byun HJ, Oh SJ, Kim CR, Park JH, Lee JH, Lee DY

No abstract available.
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A Case of Cutaneous Leukocytoclastic Vasculitis Associated with Granulocyte Colony-Stimulating Factor: An Unusual Presentation

Yoon D, Byun HJ, Oh SJ, Park JH, Lee DY

Drug-induced vasculitis is an inflammation of small-sized blood vessel caused by the use of drugs. It accounts for approximately 10% of acute cutaneous vasculitis. Propylthiouracil, hydralazine, and allopurinol have been...
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A Case of Anti-programmed Cell Death Ligand 1 and Anti-transforming Growth Factor Beta Antibody-associated Keratoacanthoma

Byun HJ, Choi Y, Park CS, Lim Y, Park S, Lee DY, Park JH

  • KMID: 2502808
  • Korean J Dermatol.
  • 2020 Mar;58(3):204-206.
Keratoacanthomas (KAs) are epithelial skin tumors characterized by rapid growth and spontaneous regression, with histopathologic features similar to those of cutaneous squamous cell carcinoma (SCC). KA arising after the use...
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A Case of Hyaline Fibromatosis Syndrome with a New Variant of Genetic Mutation in ANTXR2 Gene

Park CS, Lee J, Byun HJ, Lim Y, Park JH, Lee JH, Lee DY, Lee JH, Yang JM, Lee JH, Yoo SY

No abstract available.
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A Case of Hyaline Fibromatosis Syndrome with a New Variant of Genetic Mutation in ANTXR2 Gene

Park CS, Lee J, Byun HJ, Lim Y, Park JH, Lee JH, Lee DY, Lee JH, Yang JM, Lee JH, Yoo SY

No abstract available.
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Long Noncoding RNA N-BLR Upregulates the Migration and Invasion of Gastric Adenocarcinoma

Youn YH, Byun HJ, Yoon JH, Park CH, Lee SK

BACKGROUND/AIMS: Gastric cancer is one of the most common malignant tumors worldwide with poor prognosis due to a lack of effective treatment modalities. Recent research showed that a long noncoding...
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Chronic Exfoliative Cheilitis Successfully Treated by Pinhole Method Using COâ‚‚ Laser

Park CS, Park JH, Lee J, Byun HJ, Lim Y, Lee JH, Lee DY, Lee JH, Yang JM

No abstract available.
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A Case of Nivolumab-Induced Lichen Planus

Oh SJ, Choi YH, Byun HJ, Oh SH, Park JH, Lee JH, Lee DY, Lee JH, Yang JM

No abstract available.
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A Case of Nail Dystrophy with Selective Immunoglobulin A Deficiency

Lim Y, Lee J, Byun HJ, Park CS, Park JH, Lee JH, Lee DY

  • KMID: 2433645
  • Korean J Dermatol.
  • 2019 Jan;57(1):41-43.
No abstract available.
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A Case of Mycosis Fungoides Occurring after Primary Gamma-Delta T-Cell Lymphoma

Oh SJ, Byun HJ, Oh SH, Jun JY, Park JH, Lee JH, Lee DY, Lee JH, Yang JM

No abstract available.
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