Ann Dermatol.  2019 Jun;31(3):345-347. 10.5021/ad.2019.31.3.345.

A Case of Nivolumab-Induced Lichen Planus

• Oh SJ
• Choi YH
• Byun HJ
• Oh SH
• Park JH
• Lee JH
• Lee DY
• Lee JH
• Yang JM

• KMID: 2444872
• DOI: http://doi.org/10.5021/ad.2019.31.3.345

Abstract

No abstract available.

MeSH Terms

Lichen Planus*
Lichens*

Figure

• 

  Fig. 1 (A) Violaceous or dusky brown flat-topped plaques arrow on the patient's neck. (B) Orthokeratosis, wedge-shaped hypergranulosis, and saw-toothed irregular elongated rete ridges in the epidermis. Subepidermal cleft and lichenoid lymphocytic infiltration in the dermis (H&E, ×40). (C) Dyskeratotic cells in the epidermis (H&E, ×100).

Reference

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3. Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K. Fitzpatrick's dermatology in general medicine. 8th ed. New York: McGraw Hill Medical;2012. p. 304.

4. Komori T, Honda T, Irie H, Otsuka A, Kabashima K. Lichen planus in irradiated skin during nivolumab treatment. Acta Derm Venereol. 2017; 97:391–392.

5. Komori T, Honda T, Irie H, Otsuka A, Kabashima K. Multiple erosive lichen planus preceded by solitary lichen planus after combination therapy with nivolumab and radiation. J Eur Acad Dermatol Venereol. 2017; 31:e382–e384.